When the guardian sleeps: Reactivation of the p53 pathway in cancer.

Olaf Merkel; Ninon Taylor; Nicole Prutsch; Philipp B Staber; Richard Moriggl; Suzanne D Turner; Lukas Kenner

doi:10.1016/j.mrrev.2017.02.003

When the guardian sleeps: Reactivation of the p53 pathway in cancer.

Olaf Merkel^* (First author), Ninon Taylor (Co-author), Nicole Prutsch, Philipp B Staber, Richard Moriggl, Suzanne D Turner, Lukas Kenner

^*Corresponding author for this work

Department of Internal Medicine III - Division of Hematology, Medical Oncology, Hemostaseology, Rheumatology, Infectiology and Oncologic Center
Department of Dermatology and Allergology

Research output: Contribution to journal › Review article › peer-review

50 Citations (Web of Science)

Original language	English
Pages (from-to)	1-13
Journal	MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Volume	773
DOIs	https://doi.org/10.1016/j.mrrev.2017.02.003
Publication status	Published - 2017

Keywords

CHRONIC LYMPHOCYTIC-LEUKEMIA
CELL LUNG-CANCER
WILD-TYPE P53
SMALL-MOLECULE RITA
HUMAN TUMOR-CELLS
STRUCTURE-BASED DESIGN
MUTANT P53
IN-VIVO
PHASE-II
MDM2-P53 INTERACTION

Access to Document

10.1016/j.mrrev.2017.02.003

Cite this

@article{a35a033b0537413bb7617aaab9896f26,

title = "When the guardian sleeps: Reactivation of the p53 pathway in cancer.",

keywords = "CHRONIC LYMPHOCYTIC-LEUKEMIA, CELL LUNG-CANCER, WILD-TYPE P53, SMALL-MOLECULE RITA, HUMAN TUMOR-CELLS, STRUCTURE-BASED DESIGN, MUTANT P53, IN-VIVO, PHASE-II, MDM2-P53 INTERACTION",

author = "Olaf Merkel and Ninon Taylor and Nicole Prutsch and Staber, \{Philipp B\} and Richard Moriggl and Turner, \{Suzanne D\} and Lukas Kenner",

note = "Taylor: Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Laboratory of Immunological and Molecular Cancer Research Laboratory of Immunological and Molecular Cancer Research, Paracelsus Medical University, Salzburg, Austria",

year = "2017",

doi = "10.1016/j.mrrev.2017.02.003",

language = "English",

volume = "773",

pages = "1--13",

journal = "MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH",

issn = "1383-5742",

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TY - JOUR

T1 - When the guardian sleeps: Reactivation of the p53 pathway in cancer.

AU - Merkel, Olaf

AU - Taylor, Ninon

AU - Prutsch, Nicole

AU - Staber, Philipp B

AU - Moriggl, Richard

AU - Turner, Suzanne D

AU - Kenner, Lukas

N1 - Taylor: Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Laboratory of Immunological and Molecular Cancer Research Laboratory of Immunological and Molecular Cancer Research, Paracelsus Medical University, Salzburg, Austria

PY - 2017

Y1 - 2017

KW - CHRONIC LYMPHOCYTIC-LEUKEMIA

KW - CELL LUNG-CANCER

KW - WILD-TYPE P53

KW - SMALL-MOLECULE RITA

KW - HUMAN TUMOR-CELLS

KW - STRUCTURE-BASED DESIGN

KW - MUTANT P53

KW - IN-VIVO

KW - PHASE-II

KW - MDM2-P53 INTERACTION

U2 - 10.1016/j.mrrev.2017.02.003

DO - 10.1016/j.mrrev.2017.02.003

M3 - Review article

C2 - 28927521

SN - 1383-5742

VL - 773

SP - 1

EP - 13

JO - MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

JF - MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

ER -