Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.

Michela Tassara; Konstanze Döhner; Peter Brossart; Gerhard Held; Katharina Götze; Heinz-A Horst; Mark Ringhoffer; Claus-Henning Köhne; Stephan Kremers; Aruna Raghavachar; Gerald Wulf; Heinz Kirchen; David Nachbaur; Hans Günter Derigs; Mohammed Wattad; Elisabeth Koller; Wolfram Brugger; Axel Matzdorff; Richard Greil; Gerhard Heil; Peter Paschka; Verena I Gaidzik; Martin Göttlicher; Hartmut Döhner; Richard F Schlenk

doi:10.1182/blood-2013-12-546283

Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.

Michela Tassara, Konstanze Döhner, Peter Brossart, Gerhard Held, Katharina Götze, Heinz-A Horst, Mark Ringhoffer, Claus-Henning Köhne, Stephan Kremers, Aruna Raghavachar, Gerald Wulf, Heinz Kirchen, David Nachbaur, Hans Günter Derigs, Mohammed Wattad, Elisabeth Koller, Wolfram Brugger, Axel Matzdorff, Richard Greil (Co-author), Gerhard HeilPeter Paschka, Verena I Gaidzik, Martin Göttlicher, Hartmut Döhner, Richard F Schlenk

Department of Internal Medicine III - Division of Hematology, Medical Oncology, Hemostaseology, Rheumatology, Infectiology and Oncologic Center

Research output: Contribution to journal › Original Article › peer-review

71 Citations (Web of Science)

Original language	English
Pages (from-to)	4027-4036
Journal	BLOOD
Volume	123
Issue number	26
DOIs	https://doi.org/10.1182/blood-2013-12-546283
Publication status	Published - 2014

Keywords

HISTONE DEACETYLASE
ELDERLY-PATIENTS
HDAC INHIBITORS
EARLY DEATH
AML HD98-B
PHASE-III
TRIAL
AGE
MUTATIONS
OUTCOMES

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10.1182/blood-2013-12-546283

Cite this

Tassara, M., Döhner, K., Brossart, P., Held, G., Götze, K., Horst, H.-A., Ringhoffer, M., Köhne, C.-H., Kremers, S., Raghavachar, A., Wulf, G., Kirchen, H., Nachbaur, D., Derigs, H. G., Wattad, M., Koller, E., Brugger, W., Matzdorff, A., Greil, R., ... Schlenk, R. F. (2014). Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. BLOOD , 123(26), 4027-4036. https://doi.org/10.1182/blood-2013-12-546283

Tassara, Michela ; Döhner, Konstanze ; Brossart, Peter et al. / Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. In: BLOOD 2014 ; Vol. 123, No. 26. pp. 4027-4036.

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title = "Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.",

keywords = "HISTONE DEACETYLASE, ELDERLY-PATIENTS, HDAC INHIBITORS, EARLY DEATH, AML HD98-B, PHASE-III, TRIAL, AGE, MUTATIONS, OUTCOMES",

author = "Michela Tassara and Konstanze D{\"o}hner and Peter Brossart and Gerhard Held and Katharina G{\"o}tze and Heinz-A Horst and Mark Ringhoffer and Claus-Henning K{\"o}hne and Stephan Kremers and Aruna Raghavachar and Gerald Wulf and Heinz Kirchen and David Nachbaur and Derigs, {Hans G{\"u}nter} and Mohammed Wattad and Elisabeth Koller and Wolfram Brugger and Axel Matzdorff and Richard Greil and Gerhard Heil and Peter Paschka and Gaidzik, {Verena I} and Martin G{\"o}ttlicher and Hartmut D{\"o}hner and Schlenk, {Richard F}",

note = "19 Department of Internal Medicine III, University Hospital Salzburg, Austria; ",

year = "2014",

doi = "10.1182/blood-2013-12-546283",

language = "English",

volume = "123",

pages = "4027--4036",

journal = "BLOOD ",

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publisher = "American Society of Hematology ",

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Tassara, M, Döhner, K, Brossart, P, Held, G, Götze, K, Horst, H-A, Ringhoffer, M, Köhne, C-H, Kremers, S, Raghavachar, A, Wulf, G, Kirchen, H, Nachbaur, D, Derigs, HG, Wattad, M, Koller, E, Brugger, W, Matzdorff, A, Greil, R, Heil, G, Paschka, P, Gaidzik, VI, Göttlicher, M, Döhner, H & Schlenk, RF 2014, 'Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.', BLOOD , vol. 123, no. 26, pp. 4027-4036. https://doi.org/10.1182/blood-2013-12-546283

Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. / Tassara, Michela; Döhner, Konstanze; Brossart, Peter et al.
In: BLOOD , Vol. 123, No. 26, 2014, p. 4027-4036.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.

AU - Tassara, Michela

AU - Döhner, Konstanze

AU - Brossart, Peter

AU - Held, Gerhard

AU - Götze, Katharina

AU - Horst, Heinz-A

AU - Ringhoffer, Mark

AU - Köhne, Claus-Henning

AU - Kremers, Stephan

AU - Raghavachar, Aruna

AU - Wulf, Gerald

AU - Kirchen, Heinz

AU - Nachbaur, David

AU - Derigs, Hans Günter

AU - Wattad, Mohammed

AU - Koller, Elisabeth

AU - Brugger, Wolfram

AU - Matzdorff, Axel

AU - Greil, Richard

AU - Heil, Gerhard

AU - Paschka, Peter

AU - Gaidzik, Verena I

AU - Göttlicher, Martin

AU - Döhner, Hartmut

AU - Schlenk, Richard F

N1 - 19 Department of Internal Medicine III, University Hospital Salzburg, Austria;

PY - 2014

Y1 - 2014

KW - HISTONE DEACETYLASE

KW - ELDERLY-PATIENTS

KW - HDAC INHIBITORS

KW - EARLY DEATH

KW - AML HD98-B

KW - PHASE-III

KW - TRIAL

KW - AGE

KW - MUTATIONS

KW - OUTCOMES

U2 - 10.1182/blood-2013-12-546283

DO - 10.1182/blood-2013-12-546283

M3 - Original Article

C2 - 24797300

SN - 0006-4971

VL - 123

SP - 4027

EP - 4036

JO - BLOOD

JF - BLOOD

IS - 26

ER -

Tassara M, Döhner K, Brossart P, Held G, Götze K, Horst HA et al. Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. BLOOD . 2014;123(26):4027-4036. doi: 10.1182/blood-2013-12-546283