TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs

E Cambria; S Heusser; AC Scheuren; WK Tam; AA Karol; Wolfgang Hitzl; VY Leung; R Muller; SJ Ferguson; Karin Wuertz-Kozak

doi:10.1002/jsp2.1149

TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs

E Cambria
, S Heusser
, AC Scheuren
, WK Tam
, AA Karol
, Wolfgang Hitzl (Co-author)
, VY Leung
, R Muller
, SJ Ferguson
, Karin Wuertz-Kozak (Last author)

Research output: Contribution to journal › Original Article › peer-review

17 Citations (Web of Science)

Original language	English
Pages (from-to)	e1149
Journal	JOR Spine
DOIs	https://doi.org/10.1002/jsp2.1149
Publication status	Published - 2021

Keywords

DYNAMIC COMPRESSION
ION-CHANNEL
GENE-EXPRESSION
BONE ADAPTATION
DEGENERATION
FREQUENCY
RECEPTOR
COLLAGEN
STRESS
CHONDROCYTES

Access to Document

10.1002/jsp2.1149

Cite this

@article{6f7fea2b377f4c0186155a3fae72a277,

title = "TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs",

keywords = "DYNAMIC COMPRESSION, ION-CHANNEL, GENE-EXPRESSION, BONE ADAPTATION, DEGENERATION, FREQUENCY, RECEPTOR, COLLAGEN, STRESS, CHONDROCYTES",

author = "E Cambria and S Heusser and AC Scheuren and WK Tam and AA Karol and Wolfgang Hitzl and VY Leung and R Muller and SJ Ferguson and Karin Wuertz-Kozak",

note = "Wuertz-Kozak: Spine Center, Sch{\"o}n Klinik M{\"u}nchen Harlaching, Academic Teaching Hospital and Spine Research Institute of the Paracelsus Private Medical University Salzburg (Austria), Munich, Germany; Hitzl:Paracelsus Med Univ, Res Off Biostat, Salzburg, Austria; Paracelsus Med Univ, Dept Ophthalmol *** Optometry, Salzburg, Austria;Paracelsus Med Univ, Res Program Expt Ophthalmol *** Glaucoma Res, Salzburg, Austria; Lehr-KH: Sch{\"o}n Klinik M{\"u}nchen Harlaching,",

year = "2021",

doi = "10.1002/jsp2.1149",

language = "English",

pages = "e1149",

journal = "JOR Spine",

issn = "2572-1143",

publisher = "Wiley Verlag ",

}

TY - JOUR

T1 - TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs

AU - Cambria, E

AU - Heusser, S

AU - Scheuren, AC

AU - Tam, WK

AU - Karol, AA

AU - Hitzl, Wolfgang

AU - Leung, VY

AU - Muller, R

AU - Ferguson, SJ

AU - Wuertz-Kozak, Karin

N1 - Wuertz-Kozak: Spine Center, Schön Klinik München Harlaching, Academic Teaching Hospital and Spine Research Institute of the Paracelsus Private Medical University Salzburg (Austria), Munich, Germany; Hitzl:Paracelsus Med Univ, Res Off Biostat, Salzburg, Austria; Paracelsus Med Univ, Dept Ophthalmol *** Optometry, Salzburg, Austria;Paracelsus Med Univ, Res Program Expt Ophthalmol *** Glaucoma Res, Salzburg, Austria; Lehr-KH: Schön Klinik München Harlaching,

PY - 2021

Y1 - 2021

KW - DYNAMIC COMPRESSION

KW - ION-CHANNEL

KW - GENE-EXPRESSION

KW - BONE ADAPTATION

KW - DEGENERATION

KW - FREQUENCY

KW - RECEPTOR

KW - COLLAGEN

KW - STRESS

KW - CHONDROCYTES

U2 - 10.1002/jsp2.1149

DO - 10.1002/jsp2.1149

M3 - Original Article

SN - 2572-1143

SP - e1149

JO - JOR Spine

JF - JOR Spine

ER -