Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.

Anne Weiss; Emilie Delavenne; Carina Matias; Heimo Lagler; Daniel Simon; Ping Li; Jon U Hansen; Teresa Pires Dos Santos; Bimal Jana; Petra Priemel; Christine Bangert; Martin Bauer; Sabine Eberl; Alina Nussbaumer-Pröll; Zoe Anne Österreicher; Peter Matzneller; Tamara Quint; Maria Weber; Hanne Mørck Nielsen; Thomas Rades; Helle Krogh Johansen; Henrik Westh; Wooseong Kim; Eleftherios Mylonakis; Christian Friis; Luca Guardabassi; John Pace; Carina Vingsbo Lundberg; Fatima M"Zali; Pascal Butty; Nikolaj Sørensen; Henrik Bjørn Nielsen; Rasmus Toft-Kehler; Emma Guttman-Yassky; Georg Stingl; Markus Zeitlinger; Morten Sommer

doi:10.1002/ctm2.790

Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.

Anne Weiss
, Emilie Delavenne
, Carina Matias
, Heimo Lagler
, Daniel Simon
, Ping Li
, Jon U Hansen
, Teresa Pires Dos Santos
, Bimal Jana
, Petra Priemel
, Christine Bangert
, Martin Bauer
, Sabine Eberl
, Alina Nussbaumer-Pröll
, Zoe Anne Österreicher
, Peter Matzneller
, Tamara Quint
, Maria Weber
, Hanne Mørck Nielsen
, Thomas Rades

Helle Krogh Johansen, Henrik Westh, Wooseong Kim, Eleftherios Mylonakis, Christian Friis, Luca Guardabassi, John Pace, Carina Vingsbo Lundberg, Fatima M"Zali, Pascal Butty, Nikolaj Sørensen, Henrik Bjørn Nielsen, Rasmus Toft-Kehler, Emma Guttman-Yassky, Georg Stingl, Markus Zeitlinger, Morten Sommer

Research output: Contribution to journal › Original Article › peer-review

34 Citations (Web of Science)

Original language	English
Pages (from-to)	e790
Journal	CLINICAL AND TRANSLATIONAL MEDICINE
Volume	12
Issue number	5
DOIs	https://doi.org/10.1002/ctm2.790
Publication status	Published - 2022

Keywords

METHICILLIN-RESISTANT
ANTIBIOTIC-RESISTANCE
STRATUM-CORNEUM
FUSIDIC ACID
ALPHA-TOXIN
PREVALENCE
CHILDREN
MUPIROCIN
DISEASE
SUSCEPTIBILITY

Access to Document

10.1002/ctm2.790

Cite this

Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., ... Sommer, M. (2022). Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial. CLINICAL AND TRANSLATIONAL MEDICINE, 12(5), e790. https://doi.org/10.1002/ctm2.790

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title = "Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.",

keywords = "METHICILLIN-RESISTANT, ANTIBIOTIC-RESISTANCE, STRATUM-CORNEUM, FUSIDIC ACID, ALPHA-TOXIN, PREVALENCE, CHILDREN, MUPIROCIN, DISEASE, SUSCEPTIBILITY",

author = "Anne Weiss and Emilie Delavenne and Carina Matias and Heimo Lagler and Daniel Simon and Ping Li and Hansen, \{Jon U\} and \{Dos Santos\}, \{Teresa Pires\} and Bimal Jana and Petra Priemel and Christine Bangert and Martin Bauer and Sabine Eberl and Alina Nussbaumer-Pr{\"o}ll and \{Anne {\"O}sterreicher\}, Zoe and Peter Matzneller and Tamara Quint and Maria Weber and Nielsen, \{Hanne M{\o}rck\} and Thomas Rades and Johansen, \{Helle Krogh\} and Henrik Westh and Wooseong Kim and Eleftherios Mylonakis and Christian Friis and Luca Guardabassi and John Pace and Lundberg, \{Carina Vingsbo\} and Fatima M{"}Zali and Pascal Butty and Nikolaj S{\o}rensen and Nielsen, \{Henrik Bj{\o}rn\} and Rasmus Toft-Kehler and Emma Guttman-Yassky and Georg Stingl and Markus Zeitlinger and Morten Sommer",

note = "nicht zu werten, keine Lehr-KH Aff.",

year = "2022",

doi = "10.1002/ctm2.790",

language = "English",

volume = "12",

pages = "e790",

journal = "CLINICAL AND TRANSLATIONAL MEDICINE",

issn = "2001-1326",

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Weiss, A, Delavenne, E, Matias, C, Lagler, H, Simon, D, Li, P, Hansen, JU, Dos Santos, TP, Jana, B, Priemel, P, Bangert, C, Bauer, M, Eberl, S, Nussbaumer-Pröll, A, Anne Österreicher, Z, Matzneller, P, Quint, T, Weber, M, Nielsen, HM, Rades, T, Johansen, HK, Westh, H, Kim, W, Mylonakis, E, Friis, C, Guardabassi, L, Pace, J, Lundberg, CV, M"Zali, F, Butty, P, Sørensen, N, Nielsen, HB, Toft-Kehler, R, Guttman-Yassky, E, Stingl, G, Zeitlinger, M & Sommer, M 2022, 'Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.', CLINICAL AND TRANSLATIONAL MEDICINE, vol. 12, no. 5, pp. e790. https://doi.org/10.1002/ctm2.790

Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial. / Weiss, Anne; Delavenne, Emilie; Matias, Carina et al.
In: CLINICAL AND TRANSLATIONAL MEDICINE, Vol. 12, No. 5, 2022, p. e790.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.

AU - Weiss, Anne

AU - Delavenne, Emilie

AU - Matias, Carina

AU - Lagler, Heimo

AU - Simon, Daniel

AU - Li, Ping

AU - Hansen, Jon U

AU - Dos Santos, Teresa Pires

AU - Jana, Bimal

AU - Priemel, Petra

AU - Bangert, Christine

AU - Bauer, Martin

AU - Eberl, Sabine

AU - Nussbaumer-Pröll, Alina

AU - Anne Österreicher, Zoe

AU - Matzneller, Peter

AU - Quint, Tamara

AU - Weber, Maria

AU - Nielsen, Hanne Mørck

AU - Rades, Thomas

AU - Johansen, Helle Krogh

AU - Westh, Henrik

AU - Kim, Wooseong

AU - Mylonakis, Eleftherios

AU - Friis, Christian

AU - Guardabassi, Luca

AU - Pace, John

AU - Lundberg, Carina Vingsbo

AU - M"Zali, Fatima

AU - Butty, Pascal

AU - Sørensen, Nikolaj

AU - Nielsen, Henrik Bjørn

AU - Toft-Kehler, Rasmus

AU - Guttman-Yassky, Emma

AU - Stingl, Georg

AU - Zeitlinger, Markus

AU - Sommer, Morten

N1 - nicht zu werten, keine Lehr-KH Aff.

PY - 2022

Y1 - 2022

KW - METHICILLIN-RESISTANT

KW - ANTIBIOTIC-RESISTANCE

KW - STRATUM-CORNEUM

KW - FUSIDIC ACID

KW - ALPHA-TOXIN

KW - PREVALENCE

KW - CHILDREN

KW - MUPIROCIN

KW - DISEASE

KW - SUSCEPTIBILITY

U2 - 10.1002/ctm2.790

DO - 10.1002/ctm2.790

M3 - Original Article

C2 - 35522900

SN - 2001-1326

VL - 12

SP - e790

JO - CLINICAL AND TRANSLATIONAL MEDICINE

JF - CLINICAL AND TRANSLATIONAL MEDICINE

IS - 5

ER -