The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.

Romina M Wiedmann; Karin von Schwarzenberg; Andrea Palamidessi; Laura Schreiner; Rebekka Kubisch; Johanna Liebl; Christina Schempp; Dirk Trauner; Gyorgy Vereb; Stefan Zahler; Ernst Wagner; Rolf Müller; Giorgio Scita; Angelika M Vollmar

doi:10.1158/0008-5472.CAN-12-1772

The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.

Romina M Wiedmann, Karin von Schwarzenberg, Andrea Palamidessi, Laura Schreiner, Rebekka Kubisch, Johanna Liebl, Christina Schempp, Dirk Trauner, Gyorgy Vereb, Stefan Zahler, Ernst Wagner, Rolf Müller, Giorgio Scita, Angelika M Vollmar

Research output: Contribution to journal › Original Article › peer-review

81 Citations (Web of Science)

Original language	English
Pages (from-to)	5976-5987
Journal	CANCER RESEARCH
Volume	72
Issue number	22
DOIs	https://doi.org/10.1158/0008-5472.CAN-12-1772
Publication status	Published - 2012

Keywords

VACUOLAR H+-ATPASE
BREAST-CANCER CELLS
ARCHANGIUM-GEPHYRA
PROTON PUMPS
IN-VITRO
PROTEINS
RECEPTOR
MATRIX
MYXOBACTERIA
LYSOSOMES

Access to Document

10.1158/0008-5472.CAN-12-1772

Cite this

Wiedmann, R. M., von Schwarzenberg, K., Palamidessi, A., Schreiner, L., Kubisch, R., Liebl, J., Schempp, C., Trauner, D., Vereb, G., Zahler, S., Wagner, E., Müller, R., Scita, G., & Vollmar, A. M. (2012). The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. CANCER RESEARCH , 72(22), 5976-5987. https://doi.org/10.1158/0008-5472.CAN-12-1772

Wiedmann, Romina M ; von Schwarzenberg, Karin ; Palamidessi, Andrea et al. / The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. In: CANCER RESEARCH 2012 ; Vol. 72, No. 22. pp. 5976-5987.

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title = "The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.",

keywords = "VACUOLAR H+-ATPASE, BREAST-CANCER CELLS, ARCHANGIUM-GEPHYRA, PROTON PUMPS, IN-VITRO, PROTEINS, RECEPTOR, MATRIX, MYXOBACTERIA, LYSOSOMES",

author = "Wiedmann, {Romina M} and {von Schwarzenberg}, Karin and Andrea Palamidessi and Laura Schreiner and Rebekka Kubisch and Johanna Liebl and Christina Schempp and Dirk Trauner and Gyorgy Vereb and Stefan Zahler and Ernst Wagner and Rolf M{\"u}ller and Giorgio Scita and Vollmar, {Angelika M}",

year = "2012",

doi = "10.1158/0008-5472.CAN-12-1772",

language = "English",

volume = "72",

pages = "5976--5987",

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Wiedmann, RM, von Schwarzenberg, K, Palamidessi, A, Schreiner, L, Kubisch, R, Liebl, J, Schempp, C, Trauner, D, Vereb, G, Zahler, S, Wagner, E, Müller, R, Scita, G & Vollmar, AM 2012, 'The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.', CANCER RESEARCH , vol. 72, no. 22, pp. 5976-5987. https://doi.org/10.1158/0008-5472.CAN-12-1772

The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. / Wiedmann, Romina M; von Schwarzenberg, Karin; Palamidessi, Andrea et al.
In: CANCER RESEARCH , Vol. 72, No. 22, 2012, p. 5976-5987.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.

AU - Wiedmann, Romina M

AU - von Schwarzenberg, Karin

AU - Palamidessi, Andrea

AU - Schreiner, Laura

AU - Kubisch, Rebekka

AU - Liebl, Johanna

AU - Schempp, Christina

AU - Trauner, Dirk

AU - Vereb, Gyorgy

AU - Zahler, Stefan

AU - Wagner, Ernst

AU - Müller, Rolf

AU - Scita, Giorgio

AU - Vollmar, Angelika M

PY - 2012

Y1 - 2012

KW - VACUOLAR H+-ATPASE

KW - BREAST-CANCER CELLS

KW - ARCHANGIUM-GEPHYRA

KW - PROTON PUMPS

KW - IN-VITRO

KW - PROTEINS

KW - RECEPTOR

KW - MATRIX

KW - MYXOBACTERIA

KW - LYSOSOMES

U2 - 10.1158/0008-5472.CAN-12-1772

DO - 10.1158/0008-5472.CAN-12-1772

M3 - Original Article

C2 - 22986742

SN - 0008-5472

VL - 72

SP - 5976

EP - 5987

JO - CANCER RESEARCH

JF - CANCER RESEARCH

IS - 22

ER -

Wiedmann RM, von Schwarzenberg K, Palamidessi A, Schreiner L, Kubisch R, Liebl J et al. The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. CANCER RESEARCH . 2012;72(22):5976-5987. doi: 10.1158/0008-5472.CAN-12-1772