The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.

Aaron Javitt, Merav D Shmueli, Matthias P Kramer, Aleksandra A Kolodziejczyk, Ivan J Cohen, Lihi Radomir, Daoud Sheban, Iris Kamer, Kevin Litchfield, Elizabeta Bab-Dinitz, Oranit Zadok, Vanessa Neiens, Adi Ulman, Hila Wolf-Levy, Avital Eisenberg-Lerner, Assaf Kacen, Michal Alon, Ana Toste Rêgo, Elvira Stacher-Priehse, Michael Lindner (Co-author)Ina Koch, Jair Bar, Charles Swanton, Yardena Samuels, Yishai Levin, Paula C A da Fonseca, Eran Elinav, Nir Friedman, Silke Meiners, Yifat Merbl

Research output: Contribution to journalOriginal Article (Journal)peer-review

5 Citations (Web of Science)
Original languageEnglish
Pages (from-to)629-647
JournalNATURE CANCER
Volume4
Issue number5
DOIs
Publication statusPublished - 2023

Keywords

  • MHC CLASS-I
  • 20 S-PROTEASOMES
  • ENRICHMENT ANALYSIS
  • GAMMA-INTERFERON
  • CTLA-4 BLOCKADE
  • REVEALS
  • CANCER
  • PA28
  • EXPRESSION
  • TUMORS

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