TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.

John-Poul Ng-Blichfeldt; Tristan de Jong; Rosa K Kortekaas; Xinhui Wu; Michael Lindner; Victor Guryev; Pieter S Hiemstra; Jan Stolk; Melanie Königshoff; Reinoud Gosens

doi:10.1152/ajplung.00400.2018

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.

John-Poul Ng-Blichfeldt
, Tristan de Jong
, Rosa K Kortekaas
, Xinhui Wu
, Michael Lindner
, Victor Guryev
, Pieter S Hiemstra
, Jan Stolk
, Melanie Königshoff
, Reinoud Gosens

Department of Surgery

Research output: Contribution to journal › Original Article › peer-review

66 Citations (Web of Science)

Original language	English
Pages (from-to)	L14-L28
Journal	AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.
Volume	317
Issue number	1
DOIs	https://doi.org/10.1152/ajplung.00400.2018
Publication status	Published - 2019

Keywords

HEPATOCYTE GROWTH-FACTOR
FACTOR SCATTER FACTOR
SELF-RENEWAL
STEM-CELLS
CROSS-TALK
REPAIR
REGENERATION
EXPRESSION
PATHWAY
PROLIFERATION

Access to Document

10.1152/ajplung.00400.2018

Cite this

Ng-Blichfeldt, J.-P., de Jong, T., Kortekaas, R. K., Wu, X., Lindner, M., Guryev, V., Hiemstra, P. S., Stolk, J., Königshoff, M., & Gosens, R. (2019). TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY., 317(1), L14-L28. https://doi.org/10.1152/ajplung.00400.2018

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keywords = "HEPATOCYTE GROWTH-FACTOR, FACTOR SCATTER FACTOR, SELF-RENEWAL, STEM-CELLS, CROSS-TALK, REPAIR, REGENERATION, EXPRESSION, PATHWAY, PROLIFERATION",

author = "John-Poul Ng-Blichfeldt and \{de Jong\}, Tristan and Kortekaas, \{Rosa K\} and Xinhui Wu and Michael Lindner and Victor Guryev and Hiemstra, \{Pieter S\} and Jan Stolk and Melanie K{\"o}nigshoff and Reinoud Gosens",

year = "2019",

doi = "10.1152/ajplung.00400.2018",

language = "English",

volume = "317",

pages = "L14--L28",

journal = "AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.",

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Ng-Blichfeldt, J-P, de Jong, T, Kortekaas, RK, Wu, X, Lindner, M, Guryev, V, Hiemstra, PS, Stolk, J, Königshoff, M & Gosens, R 2019, 'TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.', AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY., vol. 317, no. 1, pp. L14-L28. https://doi.org/10.1152/ajplung.00400.2018

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. / Ng-Blichfeldt, John-Poul; de Jong, Tristan; Kortekaas, Rosa K et al.
In: AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY., Vol. 317, No. 1, 2019, p. L14-L28.

Research output: Contribution to journal › Original Article › peer-review

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T1 - TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.

AU - Ng-Blichfeldt, John-Poul

AU - de Jong, Tristan

AU - Kortekaas, Rosa K

AU - Wu, Xinhui

AU - Lindner, Michael

AU - Guryev, Victor

AU - Hiemstra, Pieter S

AU - Stolk, Jan

AU - Königshoff, Melanie

AU - Gosens, Reinoud

PY - 2019

Y1 - 2019

KW - HEPATOCYTE GROWTH-FACTOR

KW - FACTOR SCATTER FACTOR

KW - SELF-RENEWAL

KW - STEM-CELLS

KW - CROSS-TALK

KW - REPAIR

KW - REGENERATION

KW - EXPRESSION

KW - PATHWAY

KW - PROLIFERATION

U2 - 10.1152/ajplung.00400.2018

DO - 10.1152/ajplung.00400.2018

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VL - 317

SP - L14-L28

JO - AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.

JF - AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.

IS - 1

ER -