Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.

Wolfgang Gruber, Elisabeth Peer, Dominik P Elmer, Christina Sternberg, Suzana Tesanovic, Pedro Del Burgo, Sonia Coni, Gianluca Canettieri, Daniel Neureiter (Co-author), René Bartz, Hella Kohlhof, Daniel Vitt, Fritz Aberger

Research output: Contribution to journalOriginal Article (Journal)peer-review

38 Citations (Web of Science)
Original languageEnglish
Pages (from-to)968-975
JournalINTERNATIONAL JOURNAL OF CANCER
Volume142
Issue number5
DOIs
Publication statusPublished - 2018

Keywords

  • BASAL-CELL CARCINOMA
  • PATHWAY
  • MEDULLOBLASTOMA
  • ACETYLATION
  • VISMODEGIB
  • CILIA

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