Structural insights into heme binding to IL-36α proinflammatory cytokine.

Amelie Wißbrock; Nishit B Goradia; Amit Kumar; Ajay Abisheck Paul George; Toni Kühl; Peter Bellstedt; Ramadurai Ramachandran; Patrick Hoffmann; Kerstin Galler; Jürgen Popp; Ute Neugebauer; Kornelia Hampel; Bastian Zimmermann; Susanne Adam; Maximilian Wiendl; Gerhard Krönke; Iqbal Hamza; Stefan H Heinemann; Silke Frey; Axel Hueber; Oliver Ohlenschläger; Diana Imhof

doi:10.1038/s41598-019-53231-0

Structural insights into heme binding to IL-36α proinflammatory cytokine.

Amelie Wißbrock, Nishit B Goradia, Amit Kumar, Ajay Abisheck Paul George, Toni Kühl, Peter Bellstedt, Ramadurai Ramachandran, Patrick Hoffmann, Kerstin Galler, Jürgen Popp, Ute Neugebauer, Kornelia Hampel, Bastian Zimmermann, Susanne Adam, Maximilian Wiendl, Gerhard Krönke, Iqbal Hamza, Stefan H Heinemann, Silke Frey, Axel HueberOliver Ohlenschläger, Diana Imhof

Department of Internal Medicine V, Division of Oncology and Hematology

Research output: Contribution to journal › Original Article (Journal) › peer-review

26 Citations (Web of Science)

Original language	English
Pages (from-to)	16893
Journal	Scientific reports
Volume	9
Issue number	1
DOIs	https://doi.org/10.1038/s41598-019-53231-0
Publication status	Published - 2019

Keywords

NF-KAPPA-B
AMYLOID-BETA
ALZHEIMERS-DISEASE
REGULATORY MOTIF
PROTEIN
ANTAGONIST
ACTIVATION
AGONIST
PARAMETERIZATION
IDENTIFICATION

Access to Document

10.1038/s41598-019-53231-0

Cite this

Wißbrock, A., Goradia, N. B., Kumar, A., Paul George, A. A., Kühl, T., Bellstedt, P., Ramachandran, R., Hoffmann, P., Galler, K., Popp, J., Neugebauer, U., Hampel, K., Zimmermann, B., Adam, S., Wiendl, M., Krönke, G., Hamza, I., Heinemann, S. H., Frey, S., ... Imhof, D. (2019). Structural insights into heme binding to IL-36α proinflammatory cytokine. Scientific reports, 9(1), 16893. https://doi.org/10.1038/s41598-019-53231-0

@article{39387ae956ca4b8cafa9767617c9bb85,

title = "Structural insights into heme binding to IL-36α proinflammatory cytokine.",

keywords = "NF-KAPPA-B, AMYLOID-BETA, ALZHEIMERS-DISEASE, REGULATORY MOTIF, PROTEIN, ANTAGONIST, ACTIVATION, AGONIST, PARAMETERIZATION, IDENTIFICATION",

author = "Amelie Wi{\ss}brock and Goradia, {Nishit B} and Amit Kumar and {Paul George}, {Ajay Abisheck} and Toni K{\"u}hl and Peter Bellstedt and Ramadurai Ramachandran and Patrick Hoffmann and Kerstin Galler and J{\"u}rgen Popp and Ute Neugebauer and Kornelia Hampel and Bastian Zimmermann and Susanne Adam and Maximilian Wiendl and Gerhard Kr{\"o}nke and Iqbal Hamza and Heinemann, {Stefan H} and Silke Frey and Axel Hueber and Oliver Ohlenschl{\"a}ger and Diana Imhof",

year = "2019",

doi = "10.1038/s41598-019-53231-0",

language = "English",

volume = "9",

pages = "16893",

journal = "Scientific reports",

issn = "2045-2322",

publisher = "Nature Publishing Group ",

number = "1",

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Wißbrock, A, Goradia, NB, Kumar, A, Paul George, AA, Kühl, T, Bellstedt, P, Ramachandran, R, Hoffmann, P, Galler, K, Popp, J, Neugebauer, U, Hampel, K, Zimmermann, B, Adam, S, Wiendl, M, Krönke, G, Hamza, I, Heinemann, SH, Frey, S, Hueber, A, Ohlenschläger, O & Imhof, D 2019, 'Structural insights into heme binding to IL-36α proinflammatory cytokine.', Scientific reports, vol. 9, no. 1, pp. 16893. https://doi.org/10.1038/s41598-019-53231-0

TY - JOUR

T1 - Structural insights into heme binding to IL-36α proinflammatory cytokine.

AU - Wißbrock, Amelie

AU - Goradia, Nishit B

AU - Kumar, Amit

AU - Paul George, Ajay Abisheck

AU - Kühl, Toni

AU - Bellstedt, Peter

AU - Ramachandran, Ramadurai

AU - Hoffmann, Patrick

AU - Galler, Kerstin

AU - Popp, Jürgen

AU - Neugebauer, Ute

AU - Hampel, Kornelia

AU - Zimmermann, Bastian

AU - Adam, Susanne

AU - Wiendl, Maximilian

AU - Krönke, Gerhard

AU - Hamza, Iqbal

AU - Heinemann, Stefan H

AU - Frey, Silke

AU - Hueber, Axel

AU - Ohlenschläger, Oliver

AU - Imhof, Diana

PY - 2019

Y1 - 2019

KW - NF-KAPPA-B

KW - AMYLOID-BETA

KW - ALZHEIMERS-DISEASE

KW - REGULATORY MOTIF

KW - PROTEIN

KW - ANTAGONIST

KW - ACTIVATION

KW - AGONIST

KW - PARAMETERIZATION

KW - IDENTIFICATION

U2 - 10.1038/s41598-019-53231-0

DO - 10.1038/s41598-019-53231-0

M3 - Original Article (Journal)

C2 - 31729440

SN - 2045-2322

VL - 9

SP - 16893

JO - Scientific reports

JF - Scientific reports

IS - 1

ER -