Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

Kevin R W Ngoei; Christopher G Langendorf; Naomi X Y Ling; Ashfaqul Hoque; Swapna Varghese; Michelle A Camerino; Scott R Walker; Ylva E Bozikis; Toby A Dite; Ashley J Ovens; William Smiles; Roxane Jacobs; He Huang; Michael W Parker; John W Scott; Mark H Rider; Richard C Foitzik; Bruce E Kemp; Jonathan B Baell; Jonathan S Oakhill

doi:10.1016/j.chembiol.2018.03.008

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

Kevin R W Ngoei
, Christopher G Langendorf
, Naomi X Y Ling
, Ashfaqul Hoque
, Swapna Varghese
, Michelle A Camerino
, Scott R Walker
, Ylva E Bozikis
, Toby A Dite
, Ashley J Ovens
, William Smiles
, Roxane Jacobs
, He Huang
, Michael W Parker
, John W Scott
, Mark H Rider
, Richard C Foitzik
, Bruce E Kemp
, Jonathan B Baell
, Jonathan S Oakhill

Research Program of Receptor Biochemistry and Tumor Metabolism

Research output: Contribution to journal › Original Article › peer-review

48 Citations (Web of Science)

Original language	English
Pages (from-to)	728-737.e9
Journal	CELL CHEMICAL BIOLOGY
Volume	25
Issue number	6
DOIs	https://doi.org/10.1016/j.chembiol.2018.03.008
Publication status	Published - 2018

Keywords

GAMMA-SUBUNIT ISOFORMS
PROTEIN-KINASE AMPK
INSULIN
BINDING
IDENTIFICATION
CONTRACTION
EXPRESSION
EXERCISE

Access to Document

10.1016/j.chembiol.2018.03.008

Cite this

Ngoei, K. R. W., Langendorf, C. G., Ling, N. X. Y., Hoque, A., Varghese, S., Camerino, M. A., Walker, S. R., Bozikis, Y. E., Dite, T. A., Ovens, A. J., Smiles, W., Jacobs, R., Huang, H., Parker, M. W., Scott, J. W., Rider, M. H., Foitzik, R. C., Kemp, B. E., Baell, J. B., & Oakhill, J. S. (2018). Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4. CELL CHEMICAL BIOLOGY, 25(6), 728-737.e9. https://doi.org/10.1016/j.chembiol.2018.03.008

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title = "Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.",

keywords = "GAMMA-SUBUNIT ISOFORMS, PROTEIN-KINASE AMPK, INSULIN, BINDING, IDENTIFICATION, CONTRACTION, EXPRESSION, EXERCISE",

author = "Ngoei, \{Kevin R W\} and Langendorf, \{Christopher G\} and Ling, \{Naomi X Y\} and Ashfaqul Hoque and Swapna Varghese and Camerino, \{Michelle A\} and Walker, \{Scott R\} and Bozikis, \{Ylva E\} and Dite, \{Toby A\} and Ovens, \{Ashley J\} and William Smiles and Roxane Jacobs and He Huang and Parker, \{Michael W\} and Scott, \{John W\} and Rider, \{Mark H\} and Foitzik, \{Richard C\} and Kemp, \{Bruce E\} and Baell, \{Jonathan B\} and Oakhill, \{Jonathan S\}",

year = "2018",

doi = "10.1016/j.chembiol.2018.03.008",

language = "English",

volume = "25",

pages = "728--737.e9",

journal = "CELL CHEMICAL BIOLOGY",

issn = "2451-9448",

number = "6",

}

Ngoei, KRW, Langendorf, CG, Ling, NXY, Hoque, A, Varghese, S, Camerino, MA, Walker, SR, Bozikis, YE, Dite, TA, Ovens, AJ, Smiles, W, Jacobs, R, Huang, H, Parker, MW, Scott, JW, Rider, MH, Foitzik, RC, Kemp, BE, Baell, JB & Oakhill, JS 2018, 'Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.', CELL CHEMICAL BIOLOGY, vol. 25, no. 6, pp. 728-737.e9. https://doi.org/10.1016/j.chembiol.2018.03.008

TY - JOUR

T1 - Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

AU - Ngoei, Kevin R W

AU - Langendorf, Christopher G

AU - Ling, Naomi X Y

AU - Hoque, Ashfaqul

AU - Varghese, Swapna

AU - Camerino, Michelle A

AU - Walker, Scott R

AU - Bozikis, Ylva E

AU - Dite, Toby A

AU - Ovens, Ashley J

AU - Smiles, William

AU - Jacobs, Roxane

AU - Huang, He

AU - Parker, Michael W

AU - Scott, John W

AU - Rider, Mark H

AU - Foitzik, Richard C

AU - Kemp, Bruce E

AU - Baell, Jonathan B

AU - Oakhill, Jonathan S

PY - 2018

Y1 - 2018

KW - GAMMA-SUBUNIT ISOFORMS

KW - PROTEIN-KINASE AMPK

KW - INSULIN

KW - BINDING

KW - IDENTIFICATION

KW - CONTRACTION

KW - EXPRESSION

KW - EXERCISE

U2 - 10.1016/j.chembiol.2018.03.008

DO - 10.1016/j.chembiol.2018.03.008

M3 - Original Article

C2 - 29657085

SN - 2451-9448

VL - 25

SP - 728-737.e9

JO - CELL CHEMICAL BIOLOGY

JF - CELL CHEMICAL BIOLOGY

IS - 6

ER -