Serine Catabolism Feeds NADH when Respiration Is Impaired.

Lifeng Yang; Juan Carlos Garcia Canaveras; Zihong Chen; Lin Wang; Lingfan Liang; Cholsoon Jang; Johannes A. Mayr; Zhaoyue Zhang; Jonathan M Ghergurovich; Le Zhan; Shilpy Joshi; Zhixian Hu; Melanie R McReynolds; Xiaoyang Su; Eileen White; Raphael J Morscher; Joshua D Rabinowitz

doi:10.1016/j.cmet.2020.02.017

Serine Catabolism Feeds NADH when Respiration Is Impaired.

Lifeng Yang
, Juan Carlos Garcia Canaveras
, Zihong Chen
, Lin Wang
, Lingfan Liang
, Cholsoon Jang
, Johannes A. Mayr (Co-author)
, Zhaoyue Zhang
, Jonathan M Ghergurovich
, Le Zhan
, Shilpy Joshi
, Zhixian Hu
, Melanie R McReynolds
, Xiaoyang Su
, Eileen White
, Raphael J Morscher
, Joshua D Rabinowitz

Department of Pediatrics

Research output: Contribution to journal › Original Article › peer-review

153 Citations (Web of Science)

Original language	English
Pages (from-to)	809-821.e6
Journal	CELL METABOLISM
Volume	31
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2020.02.017
Publication status	Published - 2020

Keywords

ELECTRON-TRANSPORT CHAIN
REDUCTIVE CARBOXYLATION
MITOCHONDRIAL TRANSFER
CARBON METABOLISM
PYRUVATE THERAPY
CELL-GROWTH
MOUSE MODEL
TCA CYCLE
HYPOXIA
GLUTAMINE

Access to Document

10.1016/j.cmet.2020.02.017

Cite this

Yang, L., Garcia Canaveras, J. C., Chen, Z., Wang, L., Liang, L., Jang, C., Mayr, J. A., Zhang, Z., Ghergurovich, J. M., Zhan, L., Joshi, S., Hu, Z., McReynolds, M. R., Su, X., White, E., Morscher, R. J., & Rabinowitz, J. D. (2020). Serine Catabolism Feeds NADH when Respiration Is Impaired. CELL METABOLISM, 31(4), 809-821.e6. https://doi.org/10.1016/j.cmet.2020.02.017

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title = "Serine Catabolism Feeds NADH when Respiration Is Impaired.",

keywords = "ELECTRON-TRANSPORT CHAIN, REDUCTIVE CARBOXYLATION, MITOCHONDRIAL TRANSFER, CARBON METABOLISM, PYRUVATE THERAPY, CELL-GROWTH, MOUSE MODEL, TCA CYCLE, HYPOXIA, GLUTAMINE",

author = "Lifeng Yang and \{Garcia Canaveras\}, \{Juan Carlos\} and Zihong Chen and Lin Wang and Lingfan Liang and Cholsoon Jang and Mayr, \{Johannes A.\} and Zhaoyue Zhang and Ghergurovich, \{Jonathan M\} and Le Zhan and Shilpy Joshi and Zhixian Hu and McReynolds, \{Melanie R\} and Xiaoyang Su and Eileen White and Morscher, \{Raphael J\} and Rabinowitz, \{Joshua D\}",

note = "Mayr, JA: Salzburger Landeskliniken, Dept Pediat, A-5020 Salzburg, Austria; Paracelsus Med Univ, A-5020 Salzburg, Austria; ",

year = "2020",

doi = "10.1016/j.cmet.2020.02.017",

language = "English",

volume = "31",

pages = "809--821.e6",

journal = "CELL METABOLISM",

issn = "1550-4131",

publisher = "Cell Press ",

number = "4",

}

TY - JOUR

T1 - Serine Catabolism Feeds NADH when Respiration Is Impaired.

AU - Yang, Lifeng

AU - Garcia Canaveras, Juan Carlos

AU - Chen, Zihong

AU - Wang, Lin

AU - Liang, Lingfan

AU - Jang, Cholsoon

AU - Mayr, Johannes A.

AU - Zhang, Zhaoyue

AU - Ghergurovich, Jonathan M

AU - Zhan, Le

AU - Joshi, Shilpy

AU - Hu, Zhixian

AU - McReynolds, Melanie R

AU - Su, Xiaoyang

AU - White, Eileen

AU - Morscher, Raphael J

AU - Rabinowitz, Joshua D

N1 - Mayr, JA: Salzburger Landeskliniken, Dept Pediat, A-5020 Salzburg, Austria; Paracelsus Med Univ, A-5020 Salzburg, Austria;

PY - 2020

Y1 - 2020

KW - ELECTRON-TRANSPORT CHAIN

KW - REDUCTIVE CARBOXYLATION

KW - MITOCHONDRIAL TRANSFER

KW - CARBON METABOLISM

KW - PYRUVATE THERAPY

KW - CELL-GROWTH

KW - MOUSE MODEL

KW - TCA CYCLE

KW - HYPOXIA

KW - GLUTAMINE

U2 - 10.1016/j.cmet.2020.02.017

DO - 10.1016/j.cmet.2020.02.017

M3 - Original Article

C2 - 32187526

SN - 1550-4131

VL - 31

SP - 809-821.e6

JO - CELL METABOLISM

JF - CELL METABOLISM

IS - 4

ER -