Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.

Ivan Spicka; Enrique M Ocio; Heather E Oakervee; Richard Greil; Raymond H Banh; Shang-Yi Huang; James M D"Rozario; Meletios A Dimopoulos; Sara Martínez; Sonia Extremera; Carmen Kahatt; Vicente Alfaro; Angelo M Carella; Nathalie Meuleman; Roman Hájek; Argiris Symeonidis; Chang-Ki Min; Paul Cannell; Heinz Ludwig; Pieter Sonneveld; María Victoria Mateos

doi:10.1007/s00277-019-03739-2

Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.

Ivan Spicka
, Enrique M Ocio
, Heather E Oakervee
, Richard Greil (Co-author)
, Raymond H Banh
, Shang-Yi Huang
, James M D"Rozario
, Meletios A Dimopoulos
, Sara Martínez
, Sonia Extremera
, Carmen Kahatt
, Vicente Alfaro
, Angelo M Carella
, Nathalie Meuleman
, Roman Hájek
, Argiris Symeonidis
, Chang-Ki Min
, Paul Cannell
, Heinz Ludwig
, Pieter Sonneveld

María Victoria Mateos

Department of Internal Medicine III - Division of Hematology, Medical Oncology, Hemostaseology, Rheumatology, Infectiology and Oncologic Center

Research output: Contribution to journal › Original Article › peer-review

47 Citations (Web of Science)

Original language	English
Pages (from-to)	2139-2150
Journal	ANNALS OF HEMATOLOGY
Volume	98
Issue number	9
DOIs	https://doi.org/10.1007/s00277-019-03739-2
Publication status	Published - 2019

Keywords

HIGH-DOSE DEXAMETHASONE
OPEN-LABEL
IN-VITRO
BORTEZOMIB
SURVIVAL
CELLS
PANOBINOSTAT
ACTIVATION
APOPTOSIS
COMPOUND

Access to Document

10.1007/s00277-019-03739-2

Cite this

Spicka, I., Ocio, E. M., Oakervee, H. E., Greil, R., Banh, R. H., Huang, S.-Y., D"Rozario, J. M., Dimopoulos, M. A., Martínez, S., Extremera, S., Kahatt, C., Alfaro, V., Carella, A. M., Meuleman, N., Hájek, R., Symeonidis, A., Min, C.-K., Cannell, P., Ludwig, H., ... Mateos, M. V. (2019). Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma. ANNALS OF HEMATOLOGY , 98(9), 2139-2150. https://doi.org/10.1007/s00277-019-03739-2

Spicka, Ivan ; Ocio, Enrique M ; Oakervee, Heather E et al. / Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma. In: ANNALS OF HEMATOLOGY 2019 ; Vol. 98, No. 9. pp. 2139-2150.

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title = "Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.",

keywords = "HIGH-DOSE DEXAMETHASONE, OPEN-LABEL, IN-VITRO, BORTEZOMIB, SURVIVAL, CELLS, PANOBINOSTAT, ACTIVATION, APOPTOSIS, COMPOUND",

author = "Ivan Spicka and Ocio, \{Enrique M\} and Oakervee, \{Heather E\} and Richard Greil and Banh, \{Raymond H\} and Shang-Yi Huang and D{"}Rozario, \{James M\} and Dimopoulos, \{Meletios A\} and Sara Mart{\'i}nez and Sonia Extremera and Carmen Kahatt and Vicente Alfaro and Carella, \{Angelo M\} and Nathalie Meuleman and Roman H{\'a}jek and Argiris Symeonidis and Chang-Ki Min and Paul Cannell and Heinz Ludwig and Pieter Sonneveld and Mateos, \{Mar{\'i}a Victoria\}",

note = "Greil: 3rd Medical Department, Paracelsus Medical University Salzburg, Salzburg Cancer Research InstituteCancer Cluster SalzburgSalzburgAustria",

year = "2019",

doi = "10.1007/s00277-019-03739-2",

language = "English",

volume = "98",

pages = "2139--2150",

journal = "ANNALS OF HEMATOLOGY ",

issn = "0939-5555",

publisher = "Springer Nature",

number = "9",

}

Spicka, I, Ocio, EM, Oakervee, HE, Greil, R, Banh, RH, Huang, S-Y, D"Rozario, JM, Dimopoulos, MA, Martínez, S, Extremera, S, Kahatt, C, Alfaro, V, Carella, AM, Meuleman, N, Hájek, R, Symeonidis, A, Min, C-K, Cannell, P, Ludwig, H, Sonneveld, P & Mateos, MV 2019, 'Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.', ANNALS OF HEMATOLOGY , vol. 98, no. 9, pp. 2139-2150. https://doi.org/10.1007/s00277-019-03739-2

Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma. / Spicka, Ivan; Ocio, Enrique M; Oakervee, Heather E et al.
In: ANNALS OF HEMATOLOGY , Vol. 98, No. 9, 2019, p. 2139-2150.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.

AU - Spicka, Ivan

AU - Ocio, Enrique M

AU - Oakervee, Heather E

AU - Greil, Richard

AU - Banh, Raymond H

AU - Huang, Shang-Yi

AU - D"Rozario, James M

AU - Dimopoulos, Meletios A

AU - Martínez, Sara

AU - Extremera, Sonia

AU - Kahatt, Carmen

AU - Alfaro, Vicente

AU - Carella, Angelo M

AU - Meuleman, Nathalie

AU - Hájek, Roman

AU - Symeonidis, Argiris

AU - Min, Chang-Ki

AU - Cannell, Paul

AU - Ludwig, Heinz

AU - Sonneveld, Pieter

AU - Mateos, María Victoria

N1 - Greil: 3rd Medical Department, Paracelsus Medical University Salzburg, Salzburg Cancer Research InstituteCancer Cluster SalzburgSalzburgAustria

PY - 2019

Y1 - 2019

KW - HIGH-DOSE DEXAMETHASONE

KW - OPEN-LABEL

KW - IN-VITRO

KW - BORTEZOMIB

KW - SURVIVAL

KW - CELLS

KW - PANOBINOSTAT

KW - ACTIVATION

KW - APOPTOSIS

KW - COMPOUND

U2 - 10.1007/s00277-019-03739-2

DO - 10.1007/s00277-019-03739-2

M3 - Original Article

C2 - 31240472

SN - 0939-5555

VL - 98

SP - 2139

EP - 2150

JO - ANNALS OF HEMATOLOGY

JF - ANNALS OF HEMATOLOGY

IS - 9

ER -

Spicka I, Ocio EM, Oakervee HE, Greil R, Banh RH, Huang SY et al. Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma. ANNALS OF HEMATOLOGY . 2019;98(9):2139-2150. doi: 10.1007/s00277-019-03739-2