Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.

Gilles A Spoden; Ursula Rostek; Stefan Lechner; Michael Mitterberger; Sybille Mazurek; Werner Zwerschke

doi:10.1016/j.yexcr.2009.06.024

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.

Gilles A Spoden
, Ursula Rostek
, Stefan Lechner
, Michael Mitterberger
, Sybille Mazurek
, Werner Zwerschke

Department of Urology and Andrology

Research output: Contribution to journal › Original Article › peer-review

85 Citations (Web of Science)

Original language	English
Pages (from-to)	2765-2774
Journal	EXPERIMENTAL CELL RESEARCH
Volume	315
Issue number	16
DOIs	https://doi.org/10.1016/j.yexcr.2009.06.024
Publication status	Published - 2009

Keywords

HUMAN-PAPILLOMAVIRUS TYPE-16
E7 ONCOPROTEIN
CANCER-CELLS
TUMOR-GROWTH
METABOLISM
HYPOXIA
AKT
TRANSFORMATION
SURVIVAL
RAS

Access to Document

10.1016/j.yexcr.2009.06.024

Cite this

Spoden, G. A., Rostek, U., Lechner, S., Mitterberger, M., Mazurek, S., & Zwerschke, W. (2009). Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply. EXPERIMENTAL CELL RESEARCH , 315(16), 2765-2774. https://doi.org/10.1016/j.yexcr.2009.06.024

Spoden, Gilles A ; Rostek, Ursula ; Lechner, Stefan et al. / Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply. In: EXPERIMENTAL CELL RESEARCH 2009 ; Vol. 315, No. 16. pp. 2765-2774.

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title = "Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.",

keywords = "HUMAN-PAPILLOMAVIRUS TYPE-16, E7 ONCOPROTEIN, CANCER-CELLS, TUMOR-GROWTH, METABOLISM, HYPOXIA, AKT, TRANSFORMATION, SURVIVAL, RAS",

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Spoden, GA, Rostek, U, Lechner, S, Mitterberger, M, Mazurek, S & Zwerschke, W 2009, 'Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.', EXPERIMENTAL CELL RESEARCH , vol. 315, no. 16, pp. 2765-2774. https://doi.org/10.1016/j.yexcr.2009.06.024

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply. / Spoden, Gilles A; Rostek, Ursula; Lechner, Stefan et al.
In: EXPERIMENTAL CELL RESEARCH , Vol. 315, No. 16, 2009, p. 2765-2774.

Research output: Contribution to journal › Original Article › peer-review

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T1 - Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.

AU - Spoden, Gilles A

AU - Rostek, Ursula

AU - Lechner, Stefan

AU - Mitterberger, Michael

AU - Mazurek, Sybille

AU - Zwerschke, Werner

PY - 2009

Y1 - 2009

KW - HUMAN-PAPILLOMAVIRUS TYPE-16

KW - E7 ONCOPROTEIN

KW - CANCER-CELLS

KW - TUMOR-GROWTH

KW - METABOLISM

KW - HYPOXIA

KW - AKT

KW - TRANSFORMATION

KW - SURVIVAL

KW - RAS

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DO - 10.1016/j.yexcr.2009.06.024

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C2 - 19563799

SN - 0014-4827

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SP - 2765

EP - 2774

JO - EXPERIMENTAL CELL RESEARCH

JF - EXPERIMENTAL CELL RESEARCH

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Spoden GA, Rostek U, Lechner S, Mitterberger M, Mazurek S, Zwerschke W. Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply. EXPERIMENTAL CELL RESEARCH . 2009;315(16):2765-2774. doi: 10.1016/j.yexcr.2009.06.024