Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.

Meike Schneider; Julia Schüler; Rouven Höfflin; Nina Korzeniewski; Carsten Grüllich; Wilfried Roth; Dogu Teber; Boris Hadaschik; Sascha Pahernik; Markus Hohenfellner; Stefan Duensing

doi:10.1016/j.urolonc.2014.03.011

Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.

Meike Schneider
, Julia Schüler
, Rouven Höfflin
, Nina Korzeniewski
, Carsten Grüllich
, Wilfried Roth
, Dogu Teber
, Boris Hadaschik
, Sascha Pahernik
, Markus Hohenfellner
, Stefan Duensing

Department of Urology

Research output: Contribution to journal › Original Article › peer-review

10 Citations (Web of Science)

Original language	English
Pages (from-to)	877-884
Journal	UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS
Volume	32
Issue number	6
DOIs	https://doi.org/10.1016/j.urolonc.2014.03.011
Publication status	Published - 2014

Keywords

C-MET
LUNG-CANCER
TREATMENT OPTIONS
P-GLYCOPROTEIN
MUTATIONS
CRIZOTINIB
RESISTANCE
INHIBITION
EXPRESSION
SUNITINIB

Access to Document

10.1016/j.urolonc.2014.03.011

Cite this

Schneider, M., Schüler, J., Höfflin, R., Korzeniewski, N., Grüllich, C., Roth, W., Teber, D., Hadaschik, B., Pahernik, S., Hohenfellner, M., & Duensing, S. (2014). Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma. UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS, 32(6), 877-884. https://doi.org/10.1016/j.urolonc.2014.03.011

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title = "Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.",

keywords = "C-MET, LUNG-CANCER, TREATMENT OPTIONS, P-GLYCOPROTEIN, MUTATIONS, CRIZOTINIB, RESISTANCE, INHIBITION, EXPRESSION, SUNITINIB",

author = "Meike Schneider and Julia Sch{\"u}ler and Rouven H{\"o}fflin and Nina Korzeniewski and Carsten Gr{\"u}llich and Wilfried Roth and Dogu Teber and Boris Hadaschik and Sascha Pahernik and Markus Hohenfellner and Stefan Duensing",

year = "2014",

doi = "10.1016/j.urolonc.2014.03.011",

language = "English",

volume = "32",

pages = "877--884",

journal = "UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS",

issn = "1078-4139",

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Schneider, M, Schüler, J, Höfflin, R, Korzeniewski, N, Grüllich, C, Roth, W, Teber, D, Hadaschik, B, Pahernik, S, Hohenfellner, M & Duensing, S 2014, 'Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.', UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS, vol. 32, no. 6, pp. 877-884. https://doi.org/10.1016/j.urolonc.2014.03.011

Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma. / Schneider, Meike; Schüler, Julia; Höfflin, Rouven et al.
In: UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS, Vol. 32, No. 6, 2014, p. 877-884.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.

AU - Schneider, Meike

AU - Schüler, Julia

AU - Höfflin, Rouven

AU - Korzeniewski, Nina

AU - Grüllich, Carsten

AU - Roth, Wilfried

AU - Teber, Dogu

AU - Hadaschik, Boris

AU - Pahernik, Sascha

AU - Hohenfellner, Markus

AU - Duensing, Stefan

PY - 2014

Y1 - 2014

KW - C-MET

KW - LUNG-CANCER

KW - TREATMENT OPTIONS

KW - P-GLYCOPROTEIN

KW - MUTATIONS

KW - CRIZOTINIB

KW - RESISTANCE

KW - INHIBITION

KW - EXPRESSION

KW - SUNITINIB

U2 - 10.1016/j.urolonc.2014.03.011

DO - 10.1016/j.urolonc.2014.03.011

M3 - Original Article

C2 - 24929890

SN - 1078-4139

VL - 32

SP - 877

EP - 884

JO - UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS

JF - UROLOGIC ONCOLOGY - SEMINARS AND ORIGINAL INVESTIGATIONS

IS - 6

ER -