Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.

Alexander Carpinteiro; Michael J Edwards; Markus Hoffmann; Georg Kochs; Barbara Gripp; Sebastian Weigang; Constantin Adams; Elisa Carpinteiro; Anne Gulbins; Simone Keitsch; Carolin Sehl; Matthias Soddemann; Barbara Wilker; Markus Kamler; Thomas Bertsch; Karl S Lang; Sameer Patel; Gregory C Wilson; Silke Walter; Hartmut Hengel; Stefan Pöhlmann; Philipp A Lang; Johannes Kornhuber; Katrin Anne Becker; Syed A Ahmad; Klaus Fassbender; Erich Gulbins

doi:10.1016/j.xcrm.2020.100142

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.

Alexander Carpinteiro, Michael J Edwards, Markus Hoffmann, Georg Kochs, Barbara Gripp, Sebastian Weigang, Constantin Adams, Elisa Carpinteiro, Anne Gulbins, Simone Keitsch, Carolin Sehl, Matthias Soddemann, Barbara Wilker, Markus Kamler, Thomas Bertsch (Co-author), Karl S Lang, Sameer Patel, Gregory C Wilson, Silke Walter, Hartmut HengelStefan Pöhlmann, Philipp A Lang, Johannes Kornhuber, Katrin Anne Becker, Syed A Ahmad, Klaus Fassbender, Erich Gulbins

Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine - Central Laboratory

Research output: Contribution to journal › Original Article › peer-review

141 Citations (Web of Science)

Original language	English
Pages (from-to)	100142
Journal	CELL REPORTS MEDICINE
Volume	1
Issue number	8
DOIs	https://doi.org/10.1016/j.xcrm.2020.100142
Publication status	Published - 2020

Keywords

CERAMIDE
AMITRIPTYLINE
PROTEIN
CORONAVIRUS
ALPHA
SPIKE

Access to Document

10.1016/j.xcrm.2020.100142

Cite this

Carpinteiro, A., Edwards, M. J., Hoffmann, M., Kochs, G., Gripp, B., Weigang, S., Adams, C., Carpinteiro, E., Gulbins, A., Keitsch, S., Sehl, C., Soddemann, M., Wilker, B., Kamler, M., Bertsch, T., Lang, K. S., Patel, S., Wilson, G. C., Walter, S., ... Gulbins, E. (2020). Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells. CELL REPORTS MEDICINE, 1(8), 100142. https://doi.org/10.1016/j.xcrm.2020.100142

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title = "Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.",

keywords = "CERAMIDE, AMITRIPTYLINE, PROTEIN, CORONAVIRUS, ALPHA, SPIKE",

author = "Alexander Carpinteiro and Edwards, {Michael J} and Markus Hoffmann and Georg Kochs and Barbara Gripp and Sebastian Weigang and Constantin Adams and Elisa Carpinteiro and Anne Gulbins and Simone Keitsch and Carolin Sehl and Matthias Soddemann and Barbara Wilker and Markus Kamler and Thomas Bertsch and Lang, {Karl S} and Sameer Patel and Wilson, {Gregory C} and Silke Walter and Hartmut Hengel and Stefan P{\"o}hlmann and Lang, {Philipp A} and Johannes Kornhuber and Becker, {Katrin Anne} and Ahmad, {Syed A} and Klaus Fassbender and Erich Gulbins",

note = "Bertsch: Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Paracelsus Medical University, Nuremberg, Germany",

year = "2020",

doi = "10.1016/j.xcrm.2020.100142",

language = "English",

volume = "1",

pages = "100142",

journal = "CELL REPORTS MEDICINE",

issn = "2666-3791",

number = "8",

}

Carpinteiro, A, Edwards, MJ, Hoffmann, M, Kochs, G, Gripp, B, Weigang, S, Adams, C, Carpinteiro, E, Gulbins, A, Keitsch, S, Sehl, C, Soddemann, M, Wilker, B, Kamler, M, Bertsch, T, Lang, KS, Patel, S, Wilson, GC, Walter, S, Hengel, H, Pöhlmann, S, Lang, PA, Kornhuber, J, Becker, KA, Ahmad, SA, Fassbender, K & Gulbins, E 2020, 'Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.', CELL REPORTS MEDICINE, vol. 1, no. 8, pp. 100142. https://doi.org/10.1016/j.xcrm.2020.100142

TY - JOUR

T1 - Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.

AU - Carpinteiro, Alexander

AU - Edwards, Michael J

AU - Hoffmann, Markus

AU - Kochs, Georg

AU - Gripp, Barbara

AU - Weigang, Sebastian

AU - Adams, Constantin

AU - Carpinteiro, Elisa

AU - Gulbins, Anne

AU - Keitsch, Simone

AU - Sehl, Carolin

AU - Soddemann, Matthias

AU - Wilker, Barbara

AU - Kamler, Markus

AU - Bertsch, Thomas

AU - Lang, Karl S

AU - Patel, Sameer

AU - Wilson, Gregory C

AU - Walter, Silke

AU - Hengel, Hartmut

AU - Pöhlmann, Stefan

AU - Lang, Philipp A

AU - Kornhuber, Johannes

AU - Becker, Katrin Anne

AU - Ahmad, Syed A

AU - Fassbender, Klaus

AU - Gulbins, Erich

N1 - Bertsch: Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Paracelsus Medical University, Nuremberg, Germany

PY - 2020

Y1 - 2020

KW - CERAMIDE

KW - AMITRIPTYLINE

KW - PROTEIN

KW - CORONAVIRUS

KW - ALPHA

KW - SPIKE

U2 - 10.1016/j.xcrm.2020.100142

DO - 10.1016/j.xcrm.2020.100142

M3 - Original Article

C2 - 33163980

SN - 2666-3791

VL - 1

SP - 100142

JO - CELL REPORTS MEDICINE

JF - CELL REPORTS MEDICINE

IS - 8

ER -