Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.

Daniela Cerezo-Wallis; Marta Contreras-Alcalde; Kevin Troulé; Xavier Catena; Cynthia Mucientes; Tonantzin G Calvo; Estela Cañón; Cristina Tejedo; Paula C Pennacchi; Sabrina Hogan; Peter Kölblinger; Héctor Tejero; Andrew X Chen; Nuria Ibarz; Osvaldo Graña-Castro; Lola Martinez; Javier Muñoz; Pablo Ortiz-Romero; José L Rodriguez-Peralto; Gonzalo Gómez-López; Fátima Al-Shahrour; Raúl Rabadán; Mitchell P Levesque; David Olmeda; María S Soengas

doi:10.1038/s41591-020-1073-3

Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.

Daniela Cerezo-Wallis, Marta Contreras-Alcalde, Kevin Troulé, Xavier Catena, Cynthia Mucientes, Tonantzin G Calvo, Estela Cañón, Cristina Tejedo, Paula C Pennacchi, Sabrina Hogan, Peter Kölblinger (Co-author), Héctor Tejero, Andrew X Chen, Nuria Ibarz, Osvaldo Graña-Castro, Lola Martinez, Javier Muñoz, Pablo Ortiz-Romero, José L Rodriguez-Peralto, Gonzalo Gómez-LópezFátima Al-Shahrour, Raúl Rabadán, Mitchell P Levesque, David Olmeda, María S Soengas

Research output: Contribution to journal › Original Article › peer-review

95 Citations (Web of Science)

Original language	English
Pages (from-to)	1865-1877
Journal	NATURE MEDICINE
Volume	26
Issue number	12
DOIs	https://doi.org/10.1038/s41591-020-1073-3
Publication status	Published - 2020

Keywords

CELL-DIFFERENTIATION
CLINICAL-RESPONSE
CTLA-4 BLOCKADE
CANCER
INFLAMMATION
POPULATIONS
MACROPHAGES
MECHANISMS
EXPRESSION
SIGNATURES

Access to Document

10.1038/s41591-020-1073-3

Cite this

Cerezo-Wallis, D., Contreras-Alcalde, M., Troulé, K., Catena, X., Mucientes, C., Calvo, T. G., Cañón, E., Tejedo, C., Pennacchi, P. C., Hogan, S., Kölblinger, P., Tejero, H., Chen, A. X., Ibarz, N., Graña-Castro, O., Martinez, L., Muñoz, J., Ortiz-Romero, P., Rodriguez-Peralto, J. L., ... Soengas, M. S. (2020). Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. NATURE MEDICINE, 26(12), 1865-1877. https://doi.org/10.1038/s41591-020-1073-3

@article{c475266c3efb47cf83edfea16c557359,

title = "Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.",

keywords = "CELL-DIFFERENTIATION, CLINICAL-RESPONSE, CTLA-4 BLOCKADE, CANCER, INFLAMMATION, POPULATIONS, MACROPHAGES, MECHANISMS, EXPRESSION, SIGNATURES",

author = "Daniela Cerezo-Wallis and Marta Contreras-Alcalde and Kevin Troul{\'e} and Xavier Catena and Cynthia Mucientes and Calvo, \{Tonantzin G\} and Estela Ca{\~n}{\'o}n and Cristina Tejedo and Pennacchi, \{Paula C\} and Sabrina Hogan and Peter K{\"o}lblinger and H{\'e}ctor Tejero and Chen, \{Andrew X\} and Nuria Ibarz and Osvaldo Gra{\~n}a-Castro and Lola Martinez and Javier Mu{\~n}oz and Pablo Ortiz-Romero and Rodriguez-Peralto, \{Jos{\'e} L\} and Gonzalo G{\'o}mez-L{\'o}pez and F{\'a}tima Al-Shahrour and Ra{\'u}l Rabad{\'a}n and Levesque, \{Mitchell P\} and David Olmeda and Soengas, \{Mar{\'i}a S\}",

note = "K{\"o}lblinger: Department of Dermatology, University of Zurich Hospital, Zurich, Switzerland",

year = "2020",

doi = "10.1038/s41591-020-1073-3",

language = "English",

volume = "26",

pages = "1865--1877",

journal = "NATURE MEDICINE",

issn = "1078-8956",

publisher = "Springer Nature",

number = "12",

}

Cerezo-Wallis, D, Contreras-Alcalde, M, Troulé, K, Catena, X, Mucientes, C, Calvo, TG, Cañón, E, Tejedo, C, Pennacchi, PC, Hogan, S, Kölblinger, P, Tejero, H, Chen, AX, Ibarz, N, Graña-Castro, O, Martinez, L, Muñoz, J, Ortiz-Romero, P, Rodriguez-Peralto, JL, Gómez-López, G, Al-Shahrour, F, Rabadán, R, Levesque, MP, Olmeda, D & Soengas, MS 2020, 'Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.', NATURE MEDICINE, vol. 26, no. 12, pp. 1865-1877. https://doi.org/10.1038/s41591-020-1073-3

TY - JOUR

T1 - Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.

AU - Cerezo-Wallis, Daniela

AU - Contreras-Alcalde, Marta

AU - Troulé, Kevin

AU - Catena, Xavier

AU - Mucientes, Cynthia

AU - Calvo, Tonantzin G

AU - Cañón, Estela

AU - Tejedo, Cristina

AU - Pennacchi, Paula C

AU - Hogan, Sabrina

AU - Kölblinger, Peter

AU - Tejero, Héctor

AU - Chen, Andrew X

AU - Ibarz, Nuria

AU - Graña-Castro, Osvaldo

AU - Martinez, Lola

AU - Muñoz, Javier

AU - Ortiz-Romero, Pablo

AU - Rodriguez-Peralto, José L

AU - Gómez-López, Gonzalo

AU - Al-Shahrour, Fátima

AU - Rabadán, Raúl

AU - Levesque, Mitchell P

AU - Olmeda, David

AU - Soengas, María S

N1 - Kölblinger: Department of Dermatology, University of Zurich Hospital, Zurich, Switzerland

PY - 2020

Y1 - 2020

KW - CELL-DIFFERENTIATION

KW - CLINICAL-RESPONSE

KW - CTLA-4 BLOCKADE

KW - CANCER

KW - INFLAMMATION

KW - POPULATIONS

KW - MACROPHAGES

KW - MECHANISMS

KW - EXPRESSION

KW - SIGNATURES

U2 - 10.1038/s41591-020-1073-3

DO - 10.1038/s41591-020-1073-3

M3 - Original Article

C2 - 33077955

SN - 1078-8956

VL - 26

SP - 1865

EP - 1877

JO - NATURE MEDICINE

JF - NATURE MEDICINE

IS - 12

ER -