Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.

Tobias Welponer; Daniela Weber; Lisa Trattner; Birgit Tockner; Sepideh Aminzadeh-Gohari; Victoria Leb-Reichl; Anna Kaufmann; Roland Zauner; Monika Wimmer; Verena Wally; Thomas Felder; Dirk Strunk; Ulrich Koller; Johann Bauer; Barbara Kofler; Christina Guttmann-Gruber; J Piñon Hofbauer

doi:10.1111/jdv.19488

Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.

Tobias Welponer^* (First author), Daniela Weber (Co-author), Lisa Trattner (Co-author), Birgit Tockner (Co-author), Sepideh Aminzadeh-Gohari (Co-author), Victoria Leb-Reichl (Co-author), Anna Kaufmann (Co-author), Roland Zauner (Co-author), Monika Wimmer (Co-author), Verena Wally (Co-author), Thomas Felder (Co-author), Dirk Strunk (Co-author), Ulrich Koller (Co-author), Johann Bauer (Co-author), Barbara Kofler (Co-author), Christina Guttmann-Gruber (Last author), J Piñon Hofbauer^* (Last author)

^*Corresponding author for this work

Research output: Contribution to journal › Original Article (Journal) › peer-review

4 Citations (Web of Science)

Original language	English
Journal	JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
DOIs	https://doi.org/10.1111/jdv.19488
Publication status	Published - 2023

Keywords

HYPOXIA-INDUCIBLE FACTORS
CANCER
METABOLISM
RISK
HEAD
AMPK

Access to Document

10.1111/jdv.19488

Cite this

Welponer, T., Weber, D., Trattner, L., Tockner, B., Aminzadeh-Gohari, S., Leb-Reichl, V., Kaufmann, A., Zauner, R., Wimmer, M., Wally, V., Felder, T., Strunk, D., Koller, U., Bauer, J., Kofler, B., Guttmann-Gruber, C., & Hofbauer, J. P. (2023). Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY https://doi.org/10.1111/jdv.19488

Welponer, Tobias ; Weber, Daniela ; Trattner, Lisa et al. / Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma. In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 2023.

@article{28491968416c453bb664b7e544c8c276,

title = "Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.",

keywords = "HYPOXIA-INDUCIBLE FACTORS, CANCER, METABOLISM, RISK, HEAD, AMPK",

author = "Tobias Welponer and Daniela Weber and Lisa Trattner and Birgit Tockner and Sepideh Aminzadeh-Gohari and Victoria Leb-Reichl and Anna Kaufmann and Roland Zauner and Monika Wimmer and Verena Wally and Thomas Felder and Dirk Strunk and Ulrich Koller and Johann Bauer and Barbara Kofler and Christina Guttmann-Gruber and Hofbauer, {J Pi{\~n}on}",

note = "Welponer, Bauer: Department of Dermatology and Allergology, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Welponer, Trattner, Tockner, Leb-Reichl, Kaufmann, Zauner, Wimmer, Wally, Koller, Bauer, Guttmann-Gruber, Hofbauer: House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology and Allergology, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Weber, Aminzadeh-Gohari: Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Felder: Department of Laboratory Medicine, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Strunk: Cell Therapy Institute, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, Salzburg, Austria",

year = "2023",

doi = "10.1111/jdv.19488",

language = "English",

journal = "JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY ",

issn = "0926-9959",

}

Welponer, T , Weber, D , Trattner, L , Tockner, B, Aminzadeh-Gohari, S, Leb-Reichl, V , Kaufmann, A , Zauner, R , Wimmer, M , Wally, V , Felder, T , Strunk, D , Koller, U , Bauer, J , Kofler, B , Guttmann-Gruber, C & Hofbauer, JP 2023, 'Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.', JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY https://doi.org/10.1111/jdv.19488

Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma. / Welponer, Tobias (First author); Weber, Daniela (Co-author); Trattner, Lisa (Co-author) et al.
In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY , 2023.

Research output: Contribution to journal › Original Article (Journal) › peer-review

TY - JOUR

T1 - Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.

AU - Welponer, Tobias

AU - Weber, Daniela

AU - Trattner, Lisa

AU - Tockner, Birgit

AU - Aminzadeh-Gohari, Sepideh

AU - Leb-Reichl, Victoria

AU - Kaufmann, Anna

AU - Zauner, Roland

AU - Wimmer, Monika

AU - Wally, Verena

AU - Felder, Thomas

AU - Strunk, Dirk

AU - Koller, Ulrich

AU - Bauer, Johann

AU - Kofler, Barbara

AU - Guttmann-Gruber, Christina

AU - Hofbauer, J Piñon

N1 - Welponer, Bauer: Department of Dermatology and Allergology, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Welponer, Trattner, Tockner, Leb-Reichl, Kaufmann, Zauner, Wimmer, Wally, Koller, Bauer, Guttmann-Gruber, Hofbauer: House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology and Allergology, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Weber, Aminzadeh-Gohari: Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Felder: Department of Laboratory Medicine, University Hospital of the Paracelsus Medical University, Salzburg, Austria; Strunk: Cell Therapy Institute, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, Salzburg, Austria

PY - 2023

Y1 - 2023

KW - HYPOXIA-INDUCIBLE FACTORS

KW - CANCER

KW - METABOLISM

KW - RISK

KW - HEAD

KW - AMPK

U2 - 10.1111/jdv.19488

DO - 10.1111/jdv.19488

M3 - Original Article (Journal)

C2 - 37669776

SN - 0926-9959

JO - JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

JF - JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

ER -

Welponer T , Weber D , Trattner L , Tockner B, Aminzadeh-Gohari S, Leb-Reichl V et al. Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY . 2023. doi: 10.1111/jdv.19488