Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.

Teresa Kaserer; Theresa Steinacher; Roman Kainhofer; Filippo Erli; Sonja Sturm; Birgit Waltenberger; Daniela Brigitte Schuster; Mariana Spetea

doi:10.1038/s41598-020-70493-1

Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.

Teresa Kaserer, Theresa Steinacher, Roman Kainhofer, Filippo Erli, Sonja Sturm, Birgit Waltenberger, Daniela Brigitte Schuster^* (Co-author), Mariana Spetea

^*Corresponding author for this work

Insitute of Pharmacy

Research output: Contribution to journal › Original Article › peer-review

26 Citations (Web of Science)

Original language	English
Pages (from-to)	13804
Journal	Scientific reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-70493-1
Publication status	Published - 2020

Keywords

BIASED AGONISM
PROTEIN
LIGAND
CHROMATOGRAPHY
EXPLORATIONS
MITRAGYNINE
ANALGESICS
DISCOVERY
COCAINE
SITE

Access to Document

10.1038/s41598-020-70493-1

Cite this

@article{70c753e4980048edb8a36cb421ab638b,

title = "Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.",

keywords = "BIASED AGONISM, PROTEIN, LIGAND, CHROMATOGRAPHY, EXPLORATIONS, MITRAGYNINE, ANALGESICS, DISCOVERY, COCAINE, SITE",

author = "Teresa Kaserer and Theresa Steinacher and Roman Kainhofer and Filippo Erli and Sonja Sturm and Birgit Waltenberger and Schuster, {Daniela Brigitte} and Mariana Spetea",

note = "Schuster: Paracelsus Med Univ, Inst Pharm, Dept Med *** Pharmaceut Chem, Strubergasse 22, A-5020 Salzburg, Austria",

year = "2020",

doi = "10.1038/s41598-020-70493-1",

language = "English",

volume = "10",

pages = "13804",

journal = "Scientific reports",

issn = "2045-2322",

publisher = "Nature Publishing Group ",

number = "1",

}

TY - JOUR

T1 - Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.

AU - Kaserer, Teresa

AU - Steinacher, Theresa

AU - Kainhofer, Roman

AU - Erli, Filippo

AU - Sturm, Sonja

AU - Waltenberger, Birgit

AU - Schuster, Daniela Brigitte

AU - Spetea, Mariana

N1 - Schuster: Paracelsus Med Univ, Inst Pharm, Dept Med *** Pharmaceut Chem, Strubergasse 22, A-5020 Salzburg, Austria

PY - 2020

Y1 - 2020

KW - BIASED AGONISM

KW - PROTEIN

KW - LIGAND

KW - CHROMATOGRAPHY

KW - EXPLORATIONS

KW - MITRAGYNINE

KW - ANALGESICS

KW - DISCOVERY

KW - COCAINE

KW - SITE

U2 - 10.1038/s41598-020-70493-1

DO - 10.1038/s41598-020-70493-1

M3 - Original Article

C2 - 32796875

SN - 2045-2322

VL - 10

SP - 13804

JO - Scientific reports

JF - Scientific reports

IS - 1

ER -