Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.

Susanne Vrtala, Margarete Focke, Jolanta Kopec, Petra Verdino, Arnulf Josef Hartl, Wolfgang R Sperr, Alexander A Fedorov, Tanja Ball, Steve Almo, Peter Valent, Josef Thalhamer, Walter Keller, Rudolf Valenta

Research output: Contribution to journalOriginal Articlepeer-review

23 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1730-1739
JournalJOURNAL OF IMMUNOLOGY
Volume179
Issue number3
Publication statusPublished - 2007

Keywords

  • PHLEUM-PRATENSE POLLEN
  • BET V-1
  • THERAPEUTIC VACCINES
  • SECONDARY-STRUCTURE
  • RECOMBINANT GRASS
  • CELL ACTIVATION
  • SKIN-TEST
  • IMMUNOTHERAPY
  • IGE
  • ANTIBODIES

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