Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

Arne Meyer; Anna Vuorinen; Agnieszka E Zielinska; Petra Strajhar; Gareth G Lavery; Daniela Brigitte Schuster; Alex Odermatt

doi:10.1124/dmd.113.052936

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

Arne Meyer, Anna Vuorinen, Agnieszka E Zielinska, Petra Strajhar, Gareth G Lavery, Daniela Brigitte Schuster, Alex Odermatt

Research output: Contribution to journal › Original Article › peer-review

24 Citations (Web of Science)

Original language	English
Pages (from-to)	1671-1678
Journal	DRUG METABOLISM AND DISPOSITION
Volume	41
Issue number	9
DOIs	https://doi.org/10.1124/dmd.113.052936
Publication status	Published - 2013

Keywords

BETA-HYDROXYSTEROID DEHYDROGENASE
CARBONYL REDUCTION
METABOLIC SYNDROME
HUMAN LIVER
TYPE-1
PHARMACOKINETICS
INHIBITION
MICE
HYDROXYLATION
ENZYME

Access to Document

10.1124/dmd.113.052936

Cite this

@article{3f02d480a96d4e7b9b847639698e5140,

title = "Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.",

keywords = "BETA-HYDROXYSTEROID DEHYDROGENASE, CARBONYL REDUCTION, METABOLIC SYNDROME, HUMAN LIVER, TYPE-1, PHARMACOKINETICS, INHIBITION, MICE, HYDROXYLATION, ENZYME",

author = "Arne Meyer and Anna Vuorinen and Zielinska, {Agnieszka E} and Petra Strajhar and Lavery, {Gareth G} and Schuster, {Daniela Brigitte} and Alex Odermatt",

year = "2013",

doi = "10.1124/dmd.113.052936",

language = "English",

volume = "41",

pages = "1671--1678",

journal = "DRUG METABOLISM AND DISPOSITION ",

issn = "0090-9556",

number = "9",

}

TY - JOUR

T1 - Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

AU - Meyer, Arne

AU - Vuorinen, Anna

AU - Zielinska, Agnieszka E

AU - Strajhar, Petra

AU - Lavery, Gareth G

AU - Schuster, Daniela Brigitte

AU - Odermatt, Alex

PY - 2013

Y1 - 2013

KW - BETA-HYDROXYSTEROID DEHYDROGENASE

KW - CARBONYL REDUCTION

KW - METABOLIC SYNDROME

KW - HUMAN LIVER

KW - TYPE-1

KW - PHARMACOKINETICS

KW - INHIBITION

KW - MICE

KW - HYDROXYLATION

KW - ENZYME

U2 - 10.1124/dmd.113.052936

DO - 10.1124/dmd.113.052936

M3 - Original Article

C2 - 23804523

SN - 0090-9556

VL - 41

SP - 1671

EP - 1678

JO - DRUG METABOLISM AND DISPOSITION

JF - DRUG METABOLISM AND DISPOSITION

IS - 9

ER -