Evidence based noninvasive presurgical evaluation for patients with drug resistant epilepsies

Eugen Trinka* (First author), Matthias Koepp, Gudrun Kalss (Co-author), Teia Kobulashvili (Last author)

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of reviewTo review the current practices and evidence for the diagnostic accuracy and the benefits of presurgical evaluation.Recent findingsPreoperative evaluation of patients with drug-resistant focal epilepsies and subsequent epilepsy surgery leads to a significant proportion of seizure-free patients. Even those who are not completely seizure free postoperatively often experience improved quality of life with better social integration. Systematic reviews and meta-analysis on the diagnostic accuracy are available for Video-electroencephalographic (EEG) monitoring, magnetic resonance imaging (MRI), electric and magnetic source imaging, and functional MRI for lateralization of language and memory. There are currently no evidence-based international guidelines for presurgical evaluation and epilepsy surgery.SummaryPresurgical evaluation is a complex multidisciplinary and multiprofessional clinical pathway. We rely on limited consensus-based recommendations regarding the required staffing or methodological expertise in epilepsy centers.
Original languageEnglish
Pages (from-to)141-151
Number of pages11
JournalCURRENT OPINION IN NEUROLOGY
Volume37
Issue number2
DOIs
Publication statusPublished - Apr 2024

Keywords

  • Epilepsy
  • epilepsy monitoring video EEG
  • Epilepsy surgery
  • Presurgical evaluation

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