Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

Antje Appelt-Menzel; Alevtina Cubukova; Katharina Günther; Frank Edenhofer; Jörg Piontek; Gerd Krause; Tanja Stüber; Heike Walles; Winfried Neuhaus; Marco Metzger

doi:10.1016/j.stemcr.2017.02.021

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

Antje Appelt-Menzel
, Alevtina Cubukova
, Katharina Günther
, Frank Edenhofer
, Jörg Piontek
, Gerd Krause
, Tanja Stüber
, Heike Walles
, Winfried Neuhaus
, Marco Metzger

Institute of Molecular Regenerative Medicine

Research output: Contribution to journal › Original Article › peer-review

214 Citations (Web of Science)

Original language	English
Pages (from-to)	894-906
Journal	Stem Cell Reports
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/j.stemcr.2017.02.021
Publication status	Published - 2017

Keywords

TIGHT JUNCTION PROTEINS
IN-VITRO MODEL
ENDOTHELIAL-CELLS
ELECTRICAL-RESISTANCE
DRUG DISCOVERY
PERMEABILITY
GENERATION
DERIVATION
PENETRATION
EXPRESSION

Access to Document

10.1016/j.stemcr.2017.02.021

Cite this

@article{f092181e1d924862ac7d69f032bf7880,

title = "Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.",

keywords = "TIGHT JUNCTION PROTEINS, IN-VITRO MODEL, ENDOTHELIAL-CELLS, ELECTRICAL-RESISTANCE, DRUG DISCOVERY, PERMEABILITY, GENERATION, DERIVATION, PENETRATION, EXPRESSION",

author = "Antje Appelt-Menzel and Alevtina Cubukova and Katharina G{\"u}nther and Frank Edenhofer and J{\"o}rg Piontek and Gerd Krause and Tanja St{\"u}ber and Heike Walles and Winfried Neuhaus and Marco Metzger",

year = "2017",

doi = "10.1016/j.stemcr.2017.02.021",

language = "English",

volume = "8",

pages = "894--906",

journal = "Stem Cell Reports",

issn = "2213-6711",

number = "4",

}

Appelt-Menzel, A, Cubukova, A, Günther, K, Edenhofer, F, Piontek, J, Krause, G, Stüber, T, Walles, H, Neuhaus, W & Metzger, M 2017, 'Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.', Stem Cell Reports, vol. 8, no. 4, pp. 894-906. https://doi.org/10.1016/j.stemcr.2017.02.021

TY - JOUR

T1 - Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

AU - Appelt-Menzel, Antje

AU - Cubukova, Alevtina

AU - Günther, Katharina

AU - Edenhofer, Frank

AU - Piontek, Jörg

AU - Krause, Gerd

AU - Stüber, Tanja

AU - Walles, Heike

AU - Neuhaus, Winfried

AU - Metzger, Marco

PY - 2017

Y1 - 2017

KW - TIGHT JUNCTION PROTEINS

KW - IN-VITRO MODEL

KW - ENDOTHELIAL-CELLS

KW - ELECTRICAL-RESISTANCE

KW - DRUG DISCOVERY

KW - PERMEABILITY

KW - GENERATION

KW - DERIVATION

KW - PENETRATION

KW - EXPRESSION

U2 - 10.1016/j.stemcr.2017.02.021

DO - 10.1016/j.stemcr.2017.02.021

M3 - Original Article

C2 - 28344002

SN - 2213-6711

VL - 8

SP - 894

EP - 906

JO - Stem Cell Reports

JF - Stem Cell Reports

IS - 4

ER -