Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.

Marc C Hochberg; Ali Guermazi; Hans Guehring; Aida Aydemir; Stephen Wax; Patricia Fleuranceau-Morel; Asger Reinstrup Bihlet; Inger Byrjalsen; Jeppe Ragnar Andersen; Felix Eckstein

doi:10.1001/jama.2019.14735

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.

Marc C Hochberg, Ali Guermazi, Hans Guehring, Aida Aydemir, Stephen Wax, Patricia Fleuranceau-Morel, Asger Reinstrup Bihlet, Inger Byrjalsen, Jeppe Ragnar Andersen, Felix Eckstein (Last author)

Research output: Contribution to journal › Original Article › peer-review

217 Citations (Web of Science)

Original language	English
Pages (from-to)	136-1370
Journal	JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Volume	322
Issue number	14
DOIs	https://doi.org/10.1001/jama.2019.14735
Publication status	Published - 2019

Keywords

KNEE OSTEOARTHRITIS
DOUBLE-BLIND
RECOMMENDATIONS
HIP
REPLACEMENT
THERAPY
SAFETY
VOLUME
MRI

Access to Document

10.1001/jama.2019.14735

Cite this

Hochberg, M. C., Guermazi, A., Guehring, H., Aydemir, A., Wax, S., Fleuranceau-Morel, P., Reinstrup Bihlet, A., Byrjalsen, I., Ragnar Andersen, J., & Eckstein, F. (2019). Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , 322(14), 136-1370. https://doi.org/10.1001/jama.2019.14735

Hochberg, Marc C ; Guermazi, Ali ; Guehring, Hans et al. / Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial. In: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 2019 ; Vol. 322, No. 14. pp. 136-1370.

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title = "Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.",

keywords = "KNEE OSTEOARTHRITIS, DOUBLE-BLIND, RECOMMENDATIONS, HIP, REPLACEMENT, THERAPY, SAFETY, VOLUME, MRI",

author = "Hochberg, {Marc C} and Ali Guermazi and Hans Guehring and Aida Aydemir and Stephen Wax and Patricia Fleuranceau-Morel and {Reinstrup Bihlet}, Asger and Inger Byrjalsen and {Ragnar Andersen}, Jeppe and Felix Eckstein",

note = "Eckstein: Institute of Anatomy, Department of Imaging and Functional Musculoskeletal Research, Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria.",

year = "2019",

doi = "10.1001/jama.2019.14735",

language = "English",

volume = "322",

pages = "136--1370",

journal = "JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION ",

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Hochberg, MC, Guermazi, A, Guehring, H, Aydemir, A, Wax, S, Fleuranceau-Morel, P, Reinstrup Bihlet, A, Byrjalsen, I, Ragnar Andersen, J & Eckstein, F 2019, 'Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.', JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , vol. 322, no. 14, pp. 136-1370. https://doi.org/10.1001/jama.2019.14735

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial. / Hochberg, Marc C; Guermazi, Ali; Guehring, Hans et al.
In: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , Vol. 322, No. 14, 2019, p. 136-1370.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.

AU - Hochberg, Marc C

AU - Guermazi, Ali

AU - Guehring, Hans

AU - Aydemir, Aida

AU - Wax, Stephen

AU - Fleuranceau-Morel, Patricia

AU - Reinstrup Bihlet, Asger

AU - Byrjalsen, Inger

AU - Ragnar Andersen, Jeppe

AU - Eckstein, Felix

N1 - Eckstein: Institute of Anatomy, Department of Imaging and Functional Musculoskeletal Research, Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria.

PY - 2019

Y1 - 2019

KW - KNEE OSTEOARTHRITIS

KW - DOUBLE-BLIND

KW - RECOMMENDATIONS

KW - HIP

KW - REPLACEMENT

KW - THERAPY

KW - SAFETY

KW - VOLUME

KW - MRI

U2 - 10.1001/jama.2019.14735

DO - 10.1001/jama.2019.14735

M3 - Original Article

C2 - 31593273

SN - 0098-7484

VL - 322

SP - 136

EP - 1370

JO - JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JF - JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IS - 14

ER -

Hochberg MC, Guermazi A, Guehring H, Aydemir A, Wax S, Fleuranceau-Morel P et al. Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION . 2019;322(14):136-1370. doi: 10.1001/jama.2019.14735