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Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening.

  • Patrick Markt
  • , Caroline McGoohan
  • , Brian Walker
  • , Johannes Kirchmair
  • , Clemens Feldmann
  • , Gabriella De Martino
  • , Gudrun Spitzer
  • , Simona Distinto
  • , Daniela Brigitte Schuster
  • , Gerhard Wolber
  • , Christian Laggner
  • , Thierry Langer

    Research output: Contribution to journalOriginal Articlepeer-review

    19 Citations (Web of Science)
    Original languageEnglish
    Pages (from-to)1693-1705
    JournalJOURNAL OF CHEMICAL INFORMATION AND MODELING
    Volume48
    Issue number8
    DOIs
    Publication statusPublished - 2008

    Keywords

    • K INHIBITORS
    • NONCOVALENT INHIBITORS
    • ARYLAMINOETHYL AMIDES
    • CYSTEINE PROTEASES
    • DESIGN
    • POTENT
    • DOCKING
    • BINDING
    • MODELS
    • SERIES

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