Discovery of novel cathepsin S inhibitors by pharmacophore-based virtual high-throughput screening.

Patrick Markt, Caroline McGoohan, Brian Walker, Johannes Kirchmair, Clemens Feldmann, Gabriella De Martino, Gudrun Spitzer, Simona Distinto, Daniela Brigitte Schuster, Gerhard Wolber, Christian Laggner, Thierry Langer

    Research output: Contribution to journalOriginal Articlepeer-review

    18 Citations (Web of Science)
    Original languageEnglish
    Pages (from-to)1693-1705
    JournalJOURNAL OF CHEMICAL INFORMATION AND MODELING
    Volume48
    Issue number8
    DOIs
    Publication statusPublished - 2008

    Keywords

    • K INHIBITORS
    • NONCOVALENT INHIBITORS
    • ARYLAMINOETHYL AMIDES
    • CYSTEINE PROTEASES
    • DESIGN
    • POTENT
    • DOCKING
    • BINDING
    • MODELS
    • SERIES

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