Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models.

Julia Bauer; Birgit Waltenberger; Stefan M Noha; Daniela Brigitte Schuster; Judith M Rollinger; Joel Boustie; Marylene Chollet; Hermann Stuppner; Oliver Werz

doi:10.1002/cmdc.201200345

Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models.

Julia Bauer, Birgit Waltenberger, Stefan M Noha, Daniela Brigitte Schuster, Judith M Rollinger, Joel Boustie, Marylene Chollet, Hermann Stuppner, Oliver Werz

Research output: Contribution to journal › Original Article › peer-review

53 Citations (Web of Science)

Original language	English
Pages (from-to)	2077-2081
Journal	CHEMMEDCHEM
Volume	7
Issue number	12
DOIs	https://doi.org/10.1002/cmdc.201200345
Publication status	Published - 2012

Keywords

E-2 SYNTHASE-1
ANTIINFLAMMATORY DRUGS
ACTIVE-SITE
IN-VITRO
IDENTIFICATION
BIOSYNTHESIS
5-LIPOXYGENASE
METABOLITES
MPGES-1
ACID

Access to Document

10.1002/cmdc.201200345

Cite this

@article{eb34941b825747ad9204c2968f858110,

title = "Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models.",

keywords = "E-2 SYNTHASE-1, ANTIINFLAMMATORY DRUGS, ACTIVE-SITE, IN-VITRO, IDENTIFICATION, BIOSYNTHESIS, 5-LIPOXYGENASE, METABOLITES, MPGES-1, ACID",

author = "Julia Bauer and Birgit Waltenberger and Noha, \{Stefan M\} and Schuster, \{Daniela Brigitte\} and Rollinger, \{Judith M\} and Joel Boustie and Marylene Chollet and Hermann Stuppner and Oliver Werz",

year = "2012",

doi = "10.1002/cmdc.201200345",

language = "English",

volume = "7",

pages = "2077--2081",

journal = "CHEMMEDCHEM",

issn = "1860-7179",

number = "12",

}

TY - JOUR

T1 - Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models.

AU - Bauer, Julia

AU - Waltenberger, Birgit

AU - Noha, Stefan M

AU - Schuster, Daniela Brigitte

AU - Rollinger, Judith M

AU - Boustie, Joel

AU - Chollet, Marylene

AU - Stuppner, Hermann

AU - Werz, Oliver

PY - 2012

Y1 - 2012

KW - E-2 SYNTHASE-1

KW - ANTIINFLAMMATORY DRUGS

KW - ACTIVE-SITE

KW - IN-VITRO

KW - IDENTIFICATION

KW - BIOSYNTHESIS

KW - 5-LIPOXYGENASE

KW - METABOLITES

KW - MPGES-1

KW - ACID

U2 - 10.1002/cmdc.201200345

DO - 10.1002/cmdc.201200345

M3 - Original Article

C2 - 23109349

SN - 1860-7179

VL - 7

SP - 2077

EP - 2081

JO - CHEMMEDCHEM

JF - CHEMMEDCHEM

IS - 12

ER -