Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.

Mareike Lehmann; Lara Buhl; Hani N Alsafadi; Stephan Klee; Sarah Hermann; Kathrin Mutze; Chiharu Ota; Michael Lindner; Jürgen Behr; Anne Hilgendorff; Darcy E Wagner; Melanie Königshoff

doi:10.1186/s12931-018-0876-y

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.

Mareike Lehmann, Lara Buhl, Hani N Alsafadi, Stephan Klee, Sarah Hermann, Kathrin Mutze, Chiharu Ota, Michael Lindner, Jürgen Behr, Anne Hilgendorff, Darcy E Wagner, Melanie Königshoff

Department of Surgery

Research output: Contribution to journal › Original Article › peer-review

84 Citations (Web of Science)

Original language	English
Pages (from-to)	175
Journal	RESPIRATORY RESEARCH
Volume	19
Issue number	1
DOIs	https://doi.org/10.1186/s12931-018-0876-y
Publication status	Published - 2018

Keywords

TRIPLE ANGIOKINASE INHIBITOR
PROTEIN-D EXPRESSION
TGF-BETA ACTIVATION
MESENCHYMAL TRANSITION
PROLIFERATION
MODELS
INJURY
REPAIR
GENE

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10.1186/s12931-018-0876-y

Cite this

Lehmann, M., Buhl, L., Alsafadi, H. N., Klee, S., Hermann, S., Mutze, K., Ota, C., Lindner, M., Behr, J., Hilgendorff, A., Wagner, D. E., & Königshoff, M. (2018). Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis. RESPIRATORY RESEARCH, 19(1), 175. https://doi.org/10.1186/s12931-018-0876-y

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title = "Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.",

keywords = "TRIPLE ANGIOKINASE INHIBITOR, PROTEIN-D EXPRESSION, TGF-BETA ACTIVATION, MESENCHYMAL TRANSITION, PROLIFERATION, MODELS, INJURY, REPAIR, GENE",

author = "Mareike Lehmann and Lara Buhl and Alsafadi, {Hani N} and Stephan Klee and Sarah Hermann and Kathrin Mutze and Chiharu Ota and Michael Lindner and J{\"u}rgen Behr and Anne Hilgendorff and Wagner, {Darcy E} and Melanie K{\"o}nigshoff",

year = "2018",

doi = "10.1186/s12931-018-0876-y",

language = "English",

volume = "19",

pages = "175",

journal = "RESPIRATORY RESEARCH",

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Lehmann, M, Buhl, L, Alsafadi, HN, Klee, S, Hermann, S, Mutze, K, Ota, C, Lindner, M, Behr, J, Hilgendorff, A, Wagner, DE & Königshoff, M 2018, 'Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.', RESPIRATORY RESEARCH, vol. 19, no. 1, pp. 175. https://doi.org/10.1186/s12931-018-0876-y

TY - JOUR

T1 - Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.

AU - Lehmann, Mareike

AU - Buhl, Lara

AU - Alsafadi, Hani N

AU - Klee, Stephan

AU - Hermann, Sarah

AU - Mutze, Kathrin

AU - Ota, Chiharu

AU - Lindner, Michael

AU - Behr, Jürgen

AU - Hilgendorff, Anne

AU - Wagner, Darcy E

AU - Königshoff, Melanie

PY - 2018

Y1 - 2018

KW - TRIPLE ANGIOKINASE INHIBITOR

KW - PROTEIN-D EXPRESSION

KW - TGF-BETA ACTIVATION

KW - MESENCHYMAL TRANSITION

KW - PROLIFERATION

KW - MODELS

KW - INJURY

KW - REPAIR

KW - GENE

U2 - 10.1186/s12931-018-0876-y

DO - 10.1186/s12931-018-0876-y

M3 - Original Article

C2 - 30219058

SN - 1465-9921

VL - 19

SP - 175

JO - RESPIRATORY RESEARCH

JF - RESPIRATORY RESEARCH

IS - 1

ER -