Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.

André N Tiaden; Marina Klawitter; Vanda Lux; Ali Mirsaidi; Gregor Bahrenberg; Stephan Glanz; Lilian Quero; Thomas Liebscher; Karin Wuertz; Michael Ehrmann; Peter J Richards

doi:10.1074/jbc.M112.341032

Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.

André N Tiaden, Marina Klawitter, Vanda Lux, Ali Mirsaidi, Gregor Bahrenberg, Stephan Glanz, Lilian Quero, Thomas Liebscher, Karin Wuertz, Michael Ehrmann, Peter J Richards

Research output: Contribution to journal › Original Article › peer-review

61 Citations (Web of Science)

Original language	English
Pages (from-to)	2133-2145
Journal	JOURNAL OF BIOLOGICAL CHEMISTRY
Volume	287
Issue number	25
DOIs	https://doi.org/10.1074/jbc.M112.341032
Publication status	Published - 2012

Keywords

GENE-EXPRESSION
FIBRONECTIN
CELLS
CARTILAGE
MOUSE
LOCALIZATION
FRAGMENTS
MATRIX
TISSUE
PAIN

Access to Document

10.1074/jbc.M112.341032

Cite this

Tiaden, A. N., Klawitter, M., Lux, V., Mirsaidi, A., Bahrenberg, G., Glanz, S., Quero, L., Liebscher, T., Wuertz, K., Ehrmann, M., & Richards, P. J. (2012). Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. JOURNAL OF BIOLOGICAL CHEMISTRY , 287(25), 2133-2145. https://doi.org/10.1074/jbc.M112.341032

Tiaden, André N ; Klawitter, Marina ; Lux, Vanda et al. / Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. In: JOURNAL OF BIOLOGICAL CHEMISTRY 2012 ; Vol. 287, No. 25. pp. 2133-2145.

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title = "Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.",

keywords = "GENE-EXPRESSION, FIBRONECTIN, CELLS, CARTILAGE, MOUSE, LOCALIZATION, FRAGMENTS, MATRIX, TISSUE, PAIN",

author = "Tiaden, \{Andr{\'e} N\} and Marina Klawitter and Vanda Lux and Ali Mirsaidi and Gregor Bahrenberg and Stephan Glanz and Lilian Quero and Thomas Liebscher and Karin Wuertz and Michael Ehrmann and Richards, \{Peter J\}",

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Tiaden, AN, Klawitter, M, Lux, V, Mirsaidi, A, Bahrenberg, G, Glanz, S, Quero, L, Liebscher, T, Wuertz, K, Ehrmann, M & Richards, PJ 2012, 'Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.', JOURNAL OF BIOLOGICAL CHEMISTRY , vol. 287, no. 25, pp. 2133-2145. https://doi.org/10.1074/jbc.M112.341032

Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. / Tiaden, André N; Klawitter, Marina; Lux, Vanda et al.
In: JOURNAL OF BIOLOGICAL CHEMISTRY , Vol. 287, No. 25, 2012, p. 2133-2145.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.

AU - Tiaden, André N

AU - Klawitter, Marina

AU - Lux, Vanda

AU - Mirsaidi, Ali

AU - Bahrenberg, Gregor

AU - Glanz, Stephan

AU - Quero, Lilian

AU - Liebscher, Thomas

AU - Wuertz, Karin

AU - Ehrmann, Michael

AU - Richards, Peter J

PY - 2012

Y1 - 2012

KW - GENE-EXPRESSION

KW - FIBRONECTIN

KW - CELLS

KW - CARTILAGE

KW - MOUSE

KW - LOCALIZATION

KW - FRAGMENTS

KW - MATRIX

KW - TISSUE

KW - PAIN

U2 - 10.1074/jbc.M112.341032

DO - 10.1074/jbc.M112.341032

M3 - Original Article

C2 - 22556410

SN - 0021-9258

VL - 287

SP - 2133

EP - 2145

JO - JOURNAL OF BIOLOGICAL CHEMISTRY

JF - JOURNAL OF BIOLOGICAL CHEMISTRY

IS - 25

ER -

Tiaden AN, Klawitter M, Lux V, Mirsaidi A, Bahrenberg G, Glanz S et al. Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. JOURNAL OF BIOLOGICAL CHEMISTRY . 2012;287(25):2133-2145. doi: 10.1074/jbc.M112.341032