Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers

A Jahn; A Rump; TJ Widmann; C Heining; P Horak; B Hutter; N Paramasivam; S Uhrig; L Gieldon; S Drukewitz; A Kubler; M Bermudez; K Hackmann; J Porrmann; J Wagner; M Arlt; M Franke; J Fischer; Z Kowalzyk; D William; V Weth; S Oster; M Frohlich; J Hullein; CV Gonzalez; S Kreutzfeldt; A Mock; CE Heilig; DB Lipka; L Mohrmann; D Hanf; M Oles; V Teleanu; M Allgauer; L Ruhnke; O Kutz; A Knurr; A Lassmann; V Endris; O Neumann; R Penzel; K Beck; D Richter; U Winter; S Wolf; K Pfutze; C Georg; B Meissburger; I Buchhalter; Marinela Augustin; WE Aulitzky; P Hohenberger; M Kroiss; P Schirmacher; RF Schlenk; U Keilholz; F Klauschen; G Folprecht; S Bauer; JT Siveke; CH Brandts; T Kindler; M Boerries; AL Illert; N von Bubnoff; PJ Jost; KH Metzeler; M Bitzer; K Schulze-Osthoff; C von Kalle; B Brors; A Stenzinger; W Weichert; D Hubschmann; S Frohling; H Glimm; E Schrock; B Klink

doi:10.1016/j.annonc.2022.07.008

Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers

A Jahn
, A Rump
, TJ Widmann
, C Heining
, P Horak
, B Hutter
, N Paramasivam
, S Uhrig
, L Gieldon
, S Drukewitz
, A Kubler
, M Bermudez
, K Hackmann
, J Porrmann
, J Wagner
, M Arlt
, M Franke
, J Fischer
, Z Kowalzyk
, D William

V Weth, S Oster, M Frohlich, J Hullein, CV Gonzalez, S Kreutzfeldt, A Mock, CE Heilig, DB Lipka, L Mohrmann, D Hanf, M Oles, V Teleanu, M Allgauer, L Ruhnke, O Kutz, A Knurr, A Lassmann, V Endris, O Neumann, R Penzel, K Beck, D Richter, U Winter, S Wolf, K Pfutze, C Georg, B Meissburger, I Buchhalter, Marinela Augustin (Co-author), WE Aulitzky, P Hohenberger, M Kroiss, P Schirmacher, RF Schlenk, U Keilholz, F Klauschen, G Folprecht, S Bauer, JT Siveke, CH Brandts, T Kindler, M Boerries, AL Illert, N von Bubnoff, PJ Jost, KH Metzeler, M Bitzer, K Schulze-Osthoff, C von Kalle, B Brors, A Stenzinger, W Weichert, D Hubschmann, S Frohling, H Glimm, E Schrock, B Klink

Department of Internal Medicine V, Division of Oncology and Hematology

Research output: Contribution to journal › Original Article › peer-review

49 Citations (Web of Science)

Original language	English
Pages (from-to)	1186-1199
Journal	ANNALS OF ONCOLOGY
Volume	33
Issue number	11
DOIs	https://doi.org/10.1016/j.annonc.2022.07.008
Publication status	Published - 2022

Keywords

GERMLINE VARIANTS
SEQUENCE VARIANTS
MEDICAL GENETICS
AMERICAN-COLLEGE
OVARIAN-CANCER
BREAST-CANCER
GENOMICS
RISK
GENES
CLASSIFICATION

Access to Document

10.1016/j.annonc.2022.07.008

Cite this

Jahn, A., Rump, A., Widmann, TJ., Heining, C., Horak, P., Hutter, B., Paramasivam, N., Uhrig, S., Gieldon, L., Drukewitz, S., Kubler, A., Bermudez, M., Hackmann, K., Porrmann, J., Wagner, J., Arlt, M., Franke, M., Fischer, J., Kowalzyk, Z., ... Klink, B. (2022). Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers. ANNALS OF ONCOLOGY , 33(11), 1186-1199. https://doi.org/10.1016/j.annonc.2022.07.008

Jahn, A ; Rump, A ; Widmann, TJ et al. / Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers. In: ANNALS OF ONCOLOGY 2022 ; Vol. 33, No. 11. pp. 1186-1199.

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title = "Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers",

keywords = "GERMLINE VARIANTS, SEQUENCE VARIANTS, MEDICAL GENETICS, AMERICAN-COLLEGE, OVARIAN-CANCER, BREAST-CANCER, GENOMICS, RISK, GENES, CLASSIFICATION",

author = "A Jahn and A Rump and TJ Widmann and C Heining and P Horak and B Hutter and N Paramasivam and S Uhrig and L Gieldon and S Drukewitz and A Kubler and M Bermudez and K Hackmann and J Porrmann and J Wagner and M Arlt and M Franke and J Fischer and Z Kowalzyk and D William and V Weth and S Oster and M Frohlich and J Hullein and CV Gonzalez and S Kreutzfeldt and A Mock and CE Heilig and DB Lipka and L Mohrmann and D Hanf and M Oles and V Teleanu and M Allgauer and L Ruhnke and O Kutz and A Knurr and A Lassmann and V Endris and O Neumann and R Penzel and K Beck and D Richter and U Winter and S Wolf and K Pfutze and C Georg and B Meissburger and I Buchhalter and Marinela Augustin and WE Aulitzky and P Hohenberger and M Kroiss and P Schirmacher and RF Schlenk and U Keilholz and F Klauschen and G Folprecht and S Bauer and JT Siveke and CH Brandts and T Kindler and M Boerries and AL Illert and \{von Bubnoff\}, N and PJ Jost and KH Metzeler and M Bitzer and K Schulze-Osthoff and \{von Kalle\}, C and B Brors and A Stenzinger and W Weichert and D Hubschmann and S Frohling and H Glimm and E Schrock and B Klink",

note = "Augustin: Department of Hematology and Oncology, Klinikum Nuremberg, Paracelsus Medical University, Nuremberg, Germany",

year = "2022",

doi = "10.1016/j.annonc.2022.07.008",

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Jahn, A, Rump, A, Widmann, TJ, Heining, C, Horak, P, Hutter, B, Paramasivam, N, Uhrig, S, Gieldon, L, Drukewitz, S, Kubler, A, Bermudez, M, Hackmann, K, Porrmann, J, Wagner, J, Arlt, M, Franke, M, Fischer, J, Kowalzyk, Z, William, D, Weth, V, Oster, S, Frohlich, M, Hullein, J, Gonzalez, CV, Kreutzfeldt, S, Mock, A, Heilig, CE, Lipka, DB, Mohrmann, L, Hanf, D, Oles, M, Teleanu, V, Allgauer, M, Ruhnke, L, Kutz, O, Knurr, A, Lassmann, A, Endris, V, Neumann, O, Penzel, R, Beck, K, Richter, D, Winter, U, Wolf, S, Pfutze, K, Georg, C, Meissburger, B, Buchhalter, I, Augustin, M, Aulitzky, WE, Hohenberger, P, Kroiss, M, Schirmacher, P, Schlenk, RF, Keilholz, U, Klauschen, F, Folprecht, G, Bauer, S, Siveke, JT, Brandts, CH, Kindler, T, Boerries, M, Illert, AL, von Bubnoff, N, Jost, PJ, Metzeler, KH, Bitzer, M, Schulze-Osthoff, K, von Kalle, C, Brors, B, Stenzinger, A, Weichert, W, Hubschmann, D, Frohling, S, Glimm, H, Schrock, E & Klink, B 2022, 'Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers', ANNALS OF ONCOLOGY , vol. 33, no. 11, pp. 1186-1199. https://doi.org/10.1016/j.annonc.2022.07.008

Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers. / Jahn, A; Rump, A; Widmann, TJ et al.
In: ANNALS OF ONCOLOGY , Vol. 33, No. 11, 2022, p. 1186-1199.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers

AU - Jahn, A

AU - Rump, A

AU - Widmann, TJ

AU - Heining, C

AU - Horak, P

AU - Hutter, B

AU - Paramasivam, N

AU - Uhrig, S

AU - Gieldon, L

AU - Drukewitz, S

AU - Kubler, A

AU - Bermudez, M

AU - Hackmann, K

AU - Porrmann, J

AU - Wagner, J

AU - Arlt, M

AU - Franke, M

AU - Fischer, J

AU - Kowalzyk, Z

AU - William, D

AU - Weth, V

AU - Oster, S

AU - Frohlich, M

AU - Hullein, J

AU - Gonzalez, CV

AU - Kreutzfeldt, S

AU - Mock, A

AU - Heilig, CE

AU - Lipka, DB

AU - Mohrmann, L

AU - Hanf, D

AU - Oles, M

AU - Teleanu, V

AU - Allgauer, M

AU - Ruhnke, L

AU - Kutz, O

AU - Knurr, A

AU - Lassmann, A

AU - Endris, V

AU - Neumann, O

AU - Penzel, R

AU - Beck, K

AU - Richter, D

AU - Winter, U

AU - Wolf, S

AU - Pfutze, K

AU - Georg, C

AU - Meissburger, B

AU - Buchhalter, I

AU - Augustin, Marinela

AU - Aulitzky, WE

AU - Hohenberger, P

AU - Kroiss, M

AU - Schirmacher, P

AU - Schlenk, RF

AU - Keilholz, U

AU - Klauschen, F

AU - Folprecht, G

AU - Bauer, S

AU - Siveke, JT

AU - Brandts, CH

AU - Kindler, T

AU - Boerries, M

AU - Illert, AL

AU - von Bubnoff, N

AU - Jost, PJ

AU - Metzeler, KH

AU - Bitzer, M

AU - Schulze-Osthoff, K

AU - von Kalle, C

AU - Brors, B

AU - Stenzinger, A

AU - Weichert, W

AU - Hubschmann, D

AU - Frohling, S

AU - Glimm, H

AU - Schrock, E

AU - Klink, B

N1 - Augustin: Department of Hematology and Oncology, Klinikum Nuremberg, Paracelsus Medical University, Nuremberg, Germany

PY - 2022

Y1 - 2022

KW - GERMLINE VARIANTS

KW - SEQUENCE VARIANTS

KW - MEDICAL GENETICS

KW - AMERICAN-COLLEGE

KW - OVARIAN-CANCER

KW - BREAST-CANCER

KW - GENOMICS

KW - RISK

KW - GENES

KW - CLASSIFICATION

U2 - 10.1016/j.annonc.2022.07.008

DO - 10.1016/j.annonc.2022.07.008

M3 - Original Article

C2 - 35988656

SN - 0923-7534

VL - 33

SP - 1186

EP - 1199

JO - ANNALS OF ONCOLOGY

JF - ANNALS OF ONCOLOGY

IS - 11

ER -

Jahn A, Rump A, Widmann TJ, Heining C, Horak P, Hutter B et al. Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers. ANNALS OF ONCOLOGY . 2022;33(11):1186-1199. doi: 10.1016/j.annonc.2022.07.008