Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With 177Lu-PSMA

Mohsen Beheshti; Reza Vali; Soroush Zarehparvar Moghadam; HamidReza Amini; Masoumeh Hakiminejad; GhasemAli Divband

doi:10.1097/RLU.0000000000005163

Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA

Mohsen Beheshti (First author), Reza Vali, Soroush Zarehparvar Moghadam, HamidReza Amini, Masoumeh Hakiminejad, GhasemAli Divband

Department of Nuclear Medicine and Endocrinology

Research output: Contribution to journal › Case report › peer-review

Abstract

A 76-year-old man with castration-resistant prostate cancer underwent( 68)Ga-prostate-specific membrane antigen (PSMA) PET/CT for restaging. A large PSMA-avid tumor with invasion to adjacent organs was noted causing gross hematuria and symptomatic anemia. Two cycles of Lu-177-PSMA were administered, and the patient showed significant reduction of hematuria as well as declining in PSA levels. Lu-177-PSMA therapy can be a good treatment option in patients with locally invasive tumors.

Original language	English
Pages (from-to)	e276-e277
Number of pages	2
Journal	CLINICAL NUCLEAR MEDICINE
Volume	49
Issue number	6
DOIs	https://doi.org/10.1097/RLU.0000000000005163
Publication status	Published - Jun 2024

Keywords

Ga-68-PSMA PET/CT
Lu-177-PSMA
Hematuria
Local molecular endoradiotherapy
Locally advanced prostate cancer

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10.1097/RLU.0000000000005163

Cite this

Beheshti, M., Vali, R., Moghadam, S. Z., Amini, H., Hakiminejad, M., & Divband, G. (2024). Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA. CLINICAL NUCLEAR MEDICINE , 49(6), e276-e277. https://doi.org/10.1097/RLU.0000000000005163

Beheshti, Mohsen ; Vali, Reza ; Moghadam, Soroush Zarehparvar et al. / Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA. In: CLINICAL NUCLEAR MEDICINE 2024 ; Vol. 49, No. 6. pp. e276-e277.

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title = "Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With 177Lu-PSMA",

abstract = "A 76-year-old man with castration-resistant prostate cancer underwent( 68)Ga-prostate-specific membrane antigen (PSMA) PET/CT for restaging. A large PSMA-avid tumor with invasion to adjacent organs was noted causing gross hematuria and symptomatic anemia. Two cycles of Lu-177-PSMA were administered, and the patient showed significant reduction of hematuria as well as declining in PSA levels. Lu-177-PSMA therapy can be a good treatment option in patients with locally invasive tumors.",

keywords = "Ga-68-PSMA PET/CT, Lu-177-PSMA, Hematuria, Local molecular endoradiotherapy, Locally advanced prostate cancer",

author = "Mohsen Beheshti and Reza Vali and Moghadam, {Soroush Zarehparvar} and HamidReza Amini and Masoumeh Hakiminejad and GhasemAli Divband",

note = "Beheshti: Division of Molecular Imaging and Theranostics, Department of Nu- clear Medicine, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria",

year = "2024",

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doi = "10.1097/RLU.0000000000005163",

language = "English",

volume = "49",

pages = "e276--e277",

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Beheshti, M, Vali, R, Moghadam, SZ, Amini, H, Hakiminejad, M & Divband, G 2024, 'Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA', CLINICAL NUCLEAR MEDICINE , vol. 49, no. 6, pp. e276-e277. https://doi.org/10.1097/RLU.0000000000005163

Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA. / Beheshti, Mohsen (First author); Vali, Reza; Moghadam, Soroush Zarehparvar et al.
In: CLINICAL NUCLEAR MEDICINE , Vol. 49, No. 6, 06.2024, p. e276-e277.

Research output: Contribution to journal › Case report › peer-review

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T1 - Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With 177Lu-PSMA

AU - Beheshti, Mohsen

AU - Vali, Reza

AU - Moghadam, Soroush Zarehparvar

AU - Amini, HamidReza

AU - Hakiminejad, Masoumeh

AU - Divband, GhasemAli

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PY - 2024/6

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N2 - A 76-year-old man with castration-resistant prostate cancer underwent( 68)Ga-prostate-specific membrane antigen (PSMA) PET/CT for restaging. A large PSMA-avid tumor with invasion to adjacent organs was noted causing gross hematuria and symptomatic anemia. Two cycles of Lu-177-PSMA were administered, and the patient showed significant reduction of hematuria as well as declining in PSA levels. Lu-177-PSMA therapy can be a good treatment option in patients with locally invasive tumors.

AB - A 76-year-old man with castration-resistant prostate cancer underwent( 68)Ga-prostate-specific membrane antigen (PSMA) PET/CT for restaging. A large PSMA-avid tumor with invasion to adjacent organs was noted causing gross hematuria and symptomatic anemia. Two cycles of Lu-177-PSMA were administered, and the patient showed significant reduction of hematuria as well as declining in PSA levels. Lu-177-PSMA therapy can be a good treatment option in patients with locally invasive tumors.

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KW - Lu-177-PSMA

KW - Hematuria

KW - Local molecular endoradiotherapy

KW - Locally advanced prostate cancer

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Beheshti M, Vali R, Moghadam SZ, Amini H, Hakiminejad M, Divband G. Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA. CLINICAL NUCLEAR MEDICINE . 2024 Jun;49(6):e276-e277. doi: 10.1097/RLU.0000000000005163

Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With ¹⁷⁷Lu-PSMA

Abstract

Keywords

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