Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics.

Jürgen B Bulitta; Yuanyuan Jiao; Cornelia B Landersdorfer; Dhruvitkumar S Sutaria; Xun Tao; Eunjeong Shin; Rainer Höhl; Ulrike Holzgrabe; Ulrich Stephan; Fritz Sörgel

doi:10.3390/pharmaceutics11070323

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics.

Jürgen B Bulitta
, Yuanyuan Jiao
, Cornelia B Landersdorfer
, Dhruvitkumar S Sutaria
, Xun Tao
, Eunjeong Shin
, Rainer Höhl (Co-author)
, Ulrike Holzgrabe
, Ulrich Stephan
, Fritz Sörgel

Institute of Clinical Microbiology, Infectious Diseases and Infection Control

Research output: Contribution to journal › Original Article › peer-review

5 Citations (Web of Science)

Original language	English
Journal	PHARMACEUTICS
Volume	11
Issue number	7
DOIs	https://doi.org/10.3390/pharmaceutics11070323
Publication status	Published - 2019

Keywords

PHARMACODYNAMIC BREAKPOINTS
INTESTINAL ELIMINATION
ORAL BIOAVAILABILITY
GYRASE INHIBITORS
P-GLYCOPROTEIN
CIPROFLOXACIN
SECRETION
INVOLVEMENT
MECHANISM
PATHWAYS

Access to Document

10.3390/pharmaceutics11070323

Cite this

@article{35f9cd213e0f4f6aafc4c45fb4452ea5,

title = "Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics.",

keywords = "PHARMACODYNAMIC BREAKPOINTS, INTESTINAL ELIMINATION, ORAL BIOAVAILABILITY, GYRASE INHIBITORS, P-GLYCOPROTEIN, CIPROFLOXACIN, SECRETION, INVOLVEMENT, MECHANISM, PATHWAYS",

author = "Bulitta, \{J{\"u}rgen B\} and Yuanyuan Jiao and Landersdorfer, \{Cornelia B\} and Sutaria, \{Dhruvitkumar S\} and Xun Tao and Eunjeong Shin and Rainer H{\"o}hl and Ulrike Holzgrabe and Ulrich Stephan and Fritz S{\"o}rgel",

note = "H{\"o}hl: Institute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum N{\"u}rnberg, Paracelsus Medical University, N{\"u}rnberg, Germany",

year = "2019",

doi = "10.3390/pharmaceutics11070323",

language = "English",

volume = "11",

journal = "PHARMACEUTICS",

issn = "1999-4923",

publisher = "MDPI",

number = "7",

}

TY - JOUR

T1 - Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics.

AU - Bulitta, Jürgen B

AU - Jiao, Yuanyuan

AU - Landersdorfer, Cornelia B

AU - Sutaria, Dhruvitkumar S

AU - Tao, Xun

AU - Shin, Eunjeong

AU - Höhl, Rainer

AU - Holzgrabe, Ulrike

AU - Stephan, Ulrich

AU - Sörgel, Fritz

N1 - Höhl: Institute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, Nürnberg, Germany

PY - 2019

Y1 - 2019

KW - PHARMACODYNAMIC BREAKPOINTS

KW - INTESTINAL ELIMINATION

KW - ORAL BIOAVAILABILITY

KW - GYRASE INHIBITORS

KW - P-GLYCOPROTEIN

KW - CIPROFLOXACIN

KW - SECRETION

KW - INVOLVEMENT

KW - MECHANISM

KW - PATHWAYS

U2 - 10.3390/pharmaceutics11070323

DO - 10.3390/pharmaceutics11070323

M3 - Original Article

C2 - 31295857

SN - 1999-4923

VL - 11

JO - PHARMACEUTICS

JF - PHARMACEUTICS

IS - 7

ER -