Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes.

Guosheng Wu; Steffen Pfeiffer; Carsten Schröder; Tianshu Zhang; Bao N Nguyen; Sean Kelishadi; James B Atkinson; Henk-Jan Schuurman; David J G White; Agnes M Azimzadeh; Richard N Pierson

doi:10.1111/j.1399-3089.2006.00362.x

Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes.

Guosheng Wu, Steffen Pfeiffer, Carsten Schröder, Tianshu Zhang, Bao N Nguyen, Sean Kelishadi, James B Atkinson, Henk-Jan Schuurman, David J G White, Agnes M Azimzadeh, Richard N Pierson

Department of Cardiac Surgery

Research output: Contribution to journal › Original Article › peer-review

33 Citations (Web of Science)

Original language	English
Pages (from-to)	3-47
Journal	XENOTRANSPLANTATION
Volume	14
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-3089.2006.00362.x
Publication status	Published - 2007

Keywords

HYPERACUTE LUNG REJECTION
PRIMATE RENAL XENOTRANSPLANTATION
DECAY-ACCELERATING FACTOR
NATURAL ANTIBODIES
CARDIAC XENOGRAFTS
CYNOMOLGUS MONKEYS
ENDOTHELIAL-CELLS
TRANSGENIC PIGS
PORCINE KIDNEY
ALPHA-GAL

Access to Document

10.1111/j.1399-3089.2006.00362.x

Cite this

Wu, G., Pfeiffer, S., Schröder, C., Zhang, T., Nguyen, B. N., Kelishadi, S., Atkinson, J. B., Schuurman, H.-J., White, D. J. G., Azimzadeh, A. M., & Pierson, R. N. (2007). Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. XENOTRANSPLANTATION , 14(1), 3-47. https://doi.org/10.1111/j.1399-3089.2006.00362.x

Wu, Guosheng ; Pfeiffer, Steffen ; Schröder, Carsten et al. / Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. In: XENOTRANSPLANTATION 2007 ; Vol. 14, No. 1. pp. 3-47.

@article{7c9c5dc72d7e420f968a1fe9fd952c7a,

title = "Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes.",

keywords = "HYPERACUTE LUNG REJECTION, PRIMATE RENAL XENOTRANSPLANTATION, DECAY-ACCELERATING FACTOR, NATURAL ANTIBODIES, CARDIAC XENOGRAFTS, CYNOMOLGUS MONKEYS, ENDOTHELIAL-CELLS, TRANSGENIC PIGS, PORCINE KIDNEY, ALPHA-GAL",

author = "Guosheng Wu and Steffen Pfeiffer and Carsten Schr{\"o}der and Tianshu Zhang and Nguyen, {Bao N} and Sean Kelishadi and Atkinson, {James B} and Henk-Jan Schuurman and White, {David J G} and Azimzadeh, {Agnes M} and Pierson, {Richard N}",

year = "2007",

doi = "10.1111/j.1399-3089.2006.00362.x",

language = "English",

volume = "14",

pages = "3--47",

journal = "XENOTRANSPLANTATION ",

issn = "0908-665X",

number = "1",

}

Wu, G, Pfeiffer, S, Schröder, C, Zhang, T, Nguyen, BN, Kelishadi, S, Atkinson, JB, Schuurman, H-J, White, DJG, Azimzadeh, AM & Pierson, RN 2007, 'Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes.', XENOTRANSPLANTATION , vol. 14, no. 1, pp. 3-47. https://doi.org/10.1111/j.1399-3089.2006.00362.x

Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. / Wu, Guosheng; Pfeiffer, Steffen; Schröder, Carsten et al.
In: XENOTRANSPLANTATION , Vol. 14, No. 1, 2007, p. 3-47.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes.

AU - Wu, Guosheng

AU - Pfeiffer, Steffen

AU - Schröder, Carsten

AU - Zhang, Tianshu

AU - Nguyen, Bao N

AU - Kelishadi, Sean

AU - Atkinson, James B

AU - Schuurman, Henk-Jan

AU - White, David J G

AU - Azimzadeh, Agnes M

AU - Pierson, Richard N

PY - 2007

Y1 - 2007

KW - HYPERACUTE LUNG REJECTION

KW - PRIMATE RENAL XENOTRANSPLANTATION

KW - DECAY-ACCELERATING FACTOR

KW - NATURAL ANTIBODIES

KW - CARDIAC XENOGRAFTS

KW - CYNOMOLGUS MONKEYS

KW - ENDOTHELIAL-CELLS

KW - TRANSGENIC PIGS

KW - PORCINE KIDNEY

KW - ALPHA-GAL

U2 - 10.1111/j.1399-3089.2006.00362.x

DO - 10.1111/j.1399-3089.2006.00362.x

M3 - Original Article

C2 - 17214703

SN - 0908-665X

VL - 14

SP - 3

EP - 47

JO - XENOTRANSPLANTATION

JF - XENOTRANSPLANTATION

IS - 1

ER -

Wu G, Pfeiffer S, Schröder C, Zhang T, Nguyen BN, Kelishadi S et al. Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. XENOTRANSPLANTATION . 2007;14(1):3-47. doi: 10.1111/j.1399-3089.2006.00362.x