CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.

Julia Christine Gutjahr; Elisabeth Bayer; Xiaobing Yu; Julia M Laufer; Jan P Höpner; Suzana Tesanovic; Andrea Härzschel; Georg Auer; Tanja Rieß; Astrid Salmhofer; Eva Szenes; Theresa Haslauer; Valerie Durand-Onayli; Andrea Ramspacher; Sandra P Pennisi; Marc Artinger; Nadja Zaborsky; Alexandre Chigaev; Fritz Aberger; Daniel Neureiter; Lisa Pleyer; Daniel F Legler; Veronique Orian-Rousseau; Richard Greil; Tanja Hartmann

doi:10.3324/haematol.2019.231944

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.

Julia Christine Gutjahr (First author), Elisabeth Bayer (First author), Xiaobing Yu, Julia M Laufer, Jan P Höpner, Suzana Tesanovic, Andrea Härzschel, Georg Auer, Tanja Rieß (Co-author), Astrid Salmhofer, Eva Szenes, Theresa Haslauer (Co-author), Valerie Durand-Onayli, Andrea Ramspacher (Co-author), Sandra P Pennisi, Marc Artinger, Nadja Zaborsky (Co-author), Alexandre Chigaev, Fritz Aberger, Daniel Neureiter (Co-author)Lisa Pleyer (Co-author), Daniel F Legler, Veronique Orian-Rousseau, Richard Greil (Co-author), Tanja Hartmann^* (Last author)

^*Corresponding author for this work

Research output: Contribution to journal › Original Article (Journal) › peer-review

18 Citations (Web of Science)

Original language	English
Pages (from-to)	2102-2113
Journal	HAEMATOLOGICA
Volume	106
Issue number	8
DOIs	https://doi.org/10.3324/haematol.2019.231944
Publication status	Published - 2021

Keywords

REAL-TIME ANALYSIS
STEM-CELLS
E-SELECTIN
HEMATOPOIETIC PROGENITORS
THERAPEUTIC TARGET
INTEGRIN
SURVIVAL
NICHE
SRC
ENGRAFTMENT

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10.3324/haematol.2019.231944

Cite this

Gutjahr, J. C., Bayer, E., Yu, X., Laufer, J. M., Höpner, J. P., Tesanovic, S., Härzschel, A., Auer, G., Rieß, T., Salmhofer, A., Szenes, E., Haslauer, T., Durand-Onayli, V., Ramspacher, A., Pennisi, S. P., Artinger, M., Zaborsky, N., Chigaev, A., Aberger, F., ... Hartmann, T. (2021). CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. HAEMATOLOGICA , 106(8), 2102-2113. https://doi.org/10.3324/haematol.2019.231944

Gutjahr, Julia Christine ; Bayer, Elisabeth ; Yu, Xiaobing et al. / CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. In: HAEMATOLOGICA 2021 ; Vol. 106, No. 8. pp. 2102-2113.

@article{ed4af259b9314880be293424e909f113,

title = "CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.",

keywords = "REAL-TIME ANALYSIS, STEM-CELLS, E-SELECTIN, HEMATOPOIETIC PROGENITORS, THERAPEUTIC TARGET, INTEGRIN, SURVIVAL, NICHE, SRC, ENGRAFTMENT",

author = "Gutjahr, {Julia Christine} and Elisabeth Bayer and Xiaobing Yu and Laufer, {Julia M} and H{\"o}pner, {Jan P} and Suzana Tesanovic and Andrea H{\"a}rzschel and Georg Auer and Tanja Rie{\ss} and Astrid Salmhofer and Eva Szenes and Theresa Haslauer and Valerie Durand-Onayli and Andrea Ramspacher and Pennisi, {Sandra P} and Marc Artinger and Nadja Zaborsky and Alexandre Chigaev and Fritz Aberger and Daniel Neureiter and Lisa Pleyer and Legler, {Daniel F} and Veronique Orian-Rousseau and Richard Greil and Tanja Hartmann",

note = "Gutjahr, Bayer, H{\"o}pner, Auer, Rie{\ss}, Salmhofer, Szenes, Haslauer, Durand-Onayli, Zaborsky, Pleyer, Greil, Hartmann: Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology,Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Cancer Cluster Salzburg, Salzburg, Austria; Neureiter: Institute of Pathology, Paracelsus Medical UniversitySalzburg, Austria. Gutjahr, Bayer: contributed equally",

year = "2021",

doi = "10.3324/haematol.2019.231944",

language = "English",

volume = "106",

pages = "2102--2113",

journal = "HAEMATOLOGICA ",

issn = "0390-6078",

number = "8",

}

Gutjahr, JC, Bayer, E, Yu, X, Laufer, JM, Höpner, JP, Tesanovic, S, Härzschel, A, Auer, G, Rieß, T, Salmhofer, A, Szenes, E, Haslauer, T, Durand-Onayli, V, Ramspacher, A, Pennisi, SP, Artinger, M, Zaborsky, N, Chigaev, A, Aberger, F, Neureiter, D , Pleyer, L, Legler, DF, Orian-Rousseau, V, Greil, R & Hartmann, T 2021, 'CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.', HAEMATOLOGICA , vol. 106, no. 8, pp. 2102-2113. https://doi.org/10.3324/haematol.2019.231944

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. / Gutjahr, Julia Christine (First author); Bayer, Elisabeth (First author); Yu, Xiaobing et al.
In: HAEMATOLOGICA , Vol. 106, No. 8, 2021, p. 2102-2113.

Research output: Contribution to journal › Original Article (Journal) › peer-review

TY - JOUR

T1 - CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.

AU - Gutjahr, Julia Christine

AU - Bayer, Elisabeth

AU - Yu, Xiaobing

AU - Laufer, Julia M

AU - Höpner, Jan P

AU - Tesanovic, Suzana

AU - Härzschel, Andrea

AU - Auer, Georg

AU - Rieß, Tanja

AU - Salmhofer, Astrid

AU - Szenes, Eva

AU - Haslauer, Theresa

AU - Durand-Onayli, Valerie

AU - Ramspacher, Andrea

AU - Pennisi, Sandra P

AU - Artinger, Marc

AU - Zaborsky, Nadja

AU - Chigaev, Alexandre

AU - Aberger, Fritz

AU - Neureiter, Daniel

AU - Pleyer, Lisa

AU - Legler, Daniel F

AU - Orian-Rousseau, Veronique

AU - Greil, Richard

AU - Hartmann, Tanja

N1 - Gutjahr, Bayer, Höpner, Auer, Rieß, Salmhofer, Szenes, Haslauer, Durand-Onayli, Zaborsky, Pleyer, Greil, Hartmann: Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology,Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Cancer Cluster Salzburg, Salzburg, Austria; Neureiter: Institute of Pathology, Paracelsus Medical UniversitySalzburg, Austria. Gutjahr, Bayer: contributed equally

PY - 2021

Y1 - 2021

KW - REAL-TIME ANALYSIS

KW - STEM-CELLS

KW - E-SELECTIN

KW - HEMATOPOIETIC PROGENITORS

KW - THERAPEUTIC TARGET

KW - INTEGRIN

KW - SURVIVAL

KW - NICHE

KW - SRC

KW - ENGRAFTMENT

U2 - 10.3324/haematol.2019.231944

DO - 10.3324/haematol.2019.231944

M3 - Original Article (Journal)

C2 - 32616529

SN - 0390-6078

VL - 106

SP - 2102

EP - 2113

JO - HAEMATOLOGICA

JF - HAEMATOLOGICA

IS - 8

ER -

Gutjahr JC, Bayer E, Yu X, Laufer JM, Höpner JP, Tesanovic S et al. CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. HAEMATOLOGICA . 2021;106(8):2102-2113. doi: 10.3324/haematol.2019.231944