CD4+ T cells contribute to neurodegeneration in Lewy body dementia

David Gate; Emma Tapp; Olivia Leventhal; Marian Shahid; Tim J Nonninger; Andrew C Yang; Katharina Strempfl; Michael Stefan Unger; Tobias Fehlmann; Hamilton Oh; Divya Channappa; Victor W Henderson; Andreas Keller; Ludwig Aigner; Douglas R Galasko; Mark M Davis; Kathleen L Poston; Tony Wyss-Coray

doi:10.1126/science.abf7266

CD4+ T cells contribute to neurodegeneration in Lewy body dementia

David Gate
, Emma Tapp
, Olivia Leventhal
, Marian Shahid
, Tim J Nonninger
, Andrew C Yang
, Katharina Strempfl (Co-author)
, Michael Stefan Unger (Co-author)
, Tobias Fehlmann
, Hamilton Oh
, Divya Channappa
, Victor W Henderson
, Andreas Keller
, Ludwig Aigner (Co-author)
, Douglas R Galasko
, Mark M Davis
, Kathleen L Poston
, Tony Wyss-Coray

Institute of Molecular Regenerative Medicine

Research output: Contribution to journal › Original Article › peer-review

182 Citations (Web of Science)

Original language	English
Pages (from-to)	868-874
Journal	SCIENCE
Volume	374
Issue number	6569
DOIs	https://doi.org/10.1126/science.abf7266
Publication status	Published - 2021

Keywords

CLINICAL DIAGNOSTIC-CRITERIA
ALPHA-SYNUCLEIN
LYMPHOCYTES
DISEASE
INHIBITOR
INFILTRATION
INFECTION
SUBSETS
T(H)17
MODEL

Access to Document

10.1126/science.abf7266

The leukotriene signaling pathway in Lewy Body Dementias
Aigner, L. (Further contributor)
1/01/19 → 1/01/23
Project: Research
The leukotriene signaling pathway in the Lewy Body Dementias
Aigner, L. (Further contributor) & Altendorfer, B. (Further contributor)
1/01/19 → 1/01/23
Project: Research

Cite this

Gate, D., Tapp, E., Leventhal, O., Shahid, M., Nonninger, T. J., Yang, A. C., Strempfl, K., Unger, M. S., Fehlmann, T., Oh, H., Channappa, D., Henderson, V. W., Keller, A., Aigner, L., Galasko, D. R., Davis, M. M., Poston, K. L., & Wyss-Coray, T. (2021). CD4+ T cells contribute to neurodegeneration in Lewy body dementia. SCIENCE , 374(6569), 868-874. https://doi.org/10.1126/science.abf7266

Gate, David ; Tapp, Emma ; Leventhal, Olivia et al. / CD4+ T cells contribute to neurodegeneration in Lewy body dementia. In: SCIENCE 2021 ; Vol. 374, No. 6569. pp. 868-874.

@article{75b86eb41dc54628952714481e61e736,

title = "CD4+ T cells contribute to neurodegeneration in Lewy body dementia",

keywords = "CLINICAL DIAGNOSTIC-CRITERIA, ALPHA-SYNUCLEIN, LYMPHOCYTES, DISEASE, INHIBITOR, INFILTRATION, INFECTION, SUBSETS, T(H)17, MODEL",

author = "David Gate and Emma Tapp and Olivia Leventhal and Marian Shahid and Nonninger, \{Tim J\} and Yang, \{Andrew C\} and Katharina Strempfl and Unger, \{Michael Stefan\} and Tobias Fehlmann and Hamilton Oh and Divya Channappa and Henderson, \{Victor W\} and Andreas Keller and Ludwig Aigner and Galasko, \{Douglas R\} and Davis, \{Mark M\} and Poston, \{Kathleen L\} and Tony Wyss-Coray",

note = "Strempfl; Unger; Aigner: Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria; Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria",

year = "2021",

doi = "10.1126/science.abf7266",

language = "English",

volume = "374",

pages = "868--874",

journal = "SCIENCE ",

issn = "0036-8075",

number = "6569",

}

Gate, D, Tapp, E, Leventhal, O, Shahid, M, Nonninger, TJ, Yang, AC, Strempfl, K, Unger, MS, Fehlmann, T, Oh, H, Channappa, D, Henderson, VW, Keller, A, Aigner, L, Galasko, DR, Davis, MM, Poston, KL & Wyss-Coray, T 2021, 'CD4+ T cells contribute to neurodegeneration in Lewy body dementia', SCIENCE , vol. 374, no. 6569, pp. 868-874. https://doi.org/10.1126/science.abf7266

CD4+ T cells contribute to neurodegeneration in Lewy body dementia. / Gate, David; Tapp, Emma; Leventhal, Olivia et al.
In: SCIENCE , Vol. 374, No. 6569, 2021, p. 868-874.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - CD4+ T cells contribute to neurodegeneration in Lewy body dementia

AU - Gate, David

AU - Tapp, Emma

AU - Leventhal, Olivia

AU - Shahid, Marian

AU - Nonninger, Tim J

AU - Yang, Andrew C

AU - Strempfl, Katharina

AU - Unger, Michael Stefan

AU - Fehlmann, Tobias

AU - Oh, Hamilton

AU - Channappa, Divya

AU - Henderson, Victor W

AU - Keller, Andreas

AU - Aigner, Ludwig

AU - Galasko, Douglas R

AU - Davis, Mark M

AU - Poston, Kathleen L

AU - Wyss-Coray, Tony

N1 - Strempfl; Unger; Aigner: Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria; Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria

PY - 2021

Y1 - 2021

KW - CLINICAL DIAGNOSTIC-CRITERIA

KW - ALPHA-SYNUCLEIN

KW - LYMPHOCYTES

KW - DISEASE

KW - INHIBITOR

KW - INFILTRATION

KW - INFECTION

KW - SUBSETS

KW - T(H)17

KW - MODEL

U2 - 10.1126/science.abf7266

DO - 10.1126/science.abf7266

M3 - Original Article

C2 - 34648304

SN - 0036-8075

VL - 374

SP - 868

EP - 874

JO - SCIENCE

JF - SCIENCE

IS - 6569

ER -

Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC et al. CD4+ T cells contribute to neurodegeneration in Lewy body dementia. SCIENCE . 2021;374(6569):868-874. doi: 10.1126/science.abf7266

CD4+ T cells contribute to neurodegeneration in Lewy body dementia

Keywords

Access to Document

Projects

The leukotriene signaling pathway in Lewy Body Dementias

The leukotriene signaling pathway in the Lewy Body Dementias

Cite this