Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.

Georg Nübling; M Schuberth; K Feldmer; A Giese; L M Holdt; D Teupser; Stefan Lorenzl

doi:10.1007/s00221-017-4978-4

Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.

Georg Nübling, M Schuberth, K Feldmer, A Giese, L M Holdt, D Teupser, Stefan Lorenzl (Last author)

Research output: Contribution to journal › Original Article › peer-review

16 Citations (Web of Science)

Original language	English
Pages (from-to)	2407-2412
Journal	EXPERIMENTAL BRAIN RESEARCH
Volume	235
Issue number	8
DOIs	https://doi.org/10.1007/s00221-017-4978-4
Publication status	Published - 2017

Keywords

ALZHEIMERS-DISEASE
PRION PROTEIN
METAL-IONS
EXPRESSION
AGGREGATION
PROTEOLYSIS

Access to Document

10.1007/s00221-017-4978-4

Cite this

Nübling, G., Schuberth, M., Feldmer, K., Giese, A., Holdt, L. M., Teupser, D., & Lorenzl, S. (2017). Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy. EXPERIMENTAL BRAIN RESEARCH, 235(8), 2407-2412. https://doi.org/10.1007/s00221-017-4978-4

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title = "Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.",

keywords = "ALZHEIMERS-DISEASE, PRION PROTEIN, METAL-IONS, EXPRESSION, AGGREGATION, PROTEOLYSIS",

author = "Georg N{\"u}bling and M Schuberth and K Feldmer and A Giese and Holdt, {L M} and D Teupser and Stefan Lorenzl",

year = "2017",

doi = "10.1007/s00221-017-4978-4",

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Nübling, G, Schuberth, M, Feldmer, K, Giese, A, Holdt, LM, Teupser, D & Lorenzl, S 2017, 'Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy.', EXPERIMENTAL BRAIN RESEARCH, vol. 235, no. 8, pp. 2407-2412. https://doi.org/10.1007/s00221-017-4978-4

Cathepsin S increases tau oligomer formation through limited cleavage, but only IL-6, not cathespin S serum levels correlate with disease severity in the neurodegenerative tauopathy progressive supranuclear palsy. / Nübling, Georg; Schuberth, M; Feldmer, K et al.
In: EXPERIMENTAL BRAIN RESEARCH, Vol. 235, No. 8, 2017, p. 2407-2412.

Research output: Contribution to journal › Original Article › peer-review

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AU - Nübling, Georg

AU - Schuberth, M

AU - Feldmer, K

AU - Giese, A

AU - Holdt, L M

AU - Teupser, D

AU - Lorenzl, Stefan

PY - 2017

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KW - EXPRESSION

KW - AGGREGATION

KW - PROTEOLYSIS

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SN - 0014-4819

VL - 235

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JO - EXPERIMENTAL BRAIN RESEARCH

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