AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.

Michael Huemer; Stefan Rebhandl; Nadja Zaborsky; Franz J Gassner; Stefan Hainzl; Lukas Weiss; Daniel Hebenstreit; Richard Greil; Roland Geisberger

doi:10.1002/eji.201344421

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.

Michael Huemer (First author), Stefan Rebhandl (Co-author), Nadja Zaborsky (Co-author), Franz J Gassner, Stefan Hainzl (Co-author), Lukas Weiss (Co-author), Daniel Hebenstreit, Richard Greil (Co-author), Roland Geisberger^* (Last author)

^*Corresponding author for this work

Department of Dermatology and Allergology
Department of Internal Medicine III - Division of Hematology, Medical Oncology, Hemostaseology, Rheumatology, Infectiology and Oncologic Center

Research output: Contribution to journal › Original Article (Journal) › peer-review

18 Citations (Web of Science)

Original language	English
Pages (from-to)	3747-3757
Journal	EUROPEAN JOURNAL OF IMMUNOLOGY
Volume	44
Issue number	12
DOIs	https://doi.org/10.1002/eji.201344421
Publication status	Published - 2014

Keywords

INDUCED CYTIDINE DEAMINASE
V-H GENES
SOMATIC HYPERMUTATION
POOR-PROGNOSIS
HOMOLOGOUS RECOMBINATION
PROTEIN EXPRESSION
SPLICE VARIANTS
MESSENGER-RNA
B-CELLS
MUTATIONS

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10.1002/eji.201344421

Elucidating signals required for proliferation of CLL cells in vivo using a tcl1tg mouse model for the disease
Egle, A. (PI)
23/10/13 → 23/10/15
Project: Research

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Huemer, M., Rebhandl, S., Zaborsky, N., Gassner, F. J., Hainzl, S., Weiss, L., Hebenstreit, D., Greil, R., & Geisberger, R. (2014). AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells. EUROPEAN JOURNAL OF IMMUNOLOGY , 44(12), 3747-3757. https://doi.org/10.1002/eji.201344421

Huemer, Michael ; Rebhandl, Stefan ; Zaborsky, Nadja et al. / AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells. In: EUROPEAN JOURNAL OF IMMUNOLOGY 2014 ; Vol. 44, No. 12. pp. 3747-3757.

@article{aa92bf20c8da4ab5b9462370bbd2afa0,

title = "AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.",

keywords = "INDUCED CYTIDINE DEAMINASE, V-H GENES, SOMATIC HYPERMUTATION, POOR-PROGNOSIS, HOMOLOGOUS RECOMBINATION, PROTEIN EXPRESSION, SPLICE VARIANTS, MESSENGER-RNA, B-CELLS, MUTATIONS",

author = "Michael Huemer and Stefan Rebhandl and Nadja Zaborsky and Gassner, {Franz J} and Stefan Hainzl and Lukas Weiss and Daniel Hebenstreit and Richard Greil and Roland Geisberger",

note = "1 Laboratory for Immunological and Molecular Cancer Research, Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria 2 Division of Experimental Dermatology and EB House Austria, Department of Dermatology, Paracelsus Medical University, Salzburg, Austria",

year = "2014",

doi = "10.1002/eji.201344421",

language = "English",

volume = "44",

pages = "3747--3757",

journal = "EUROPEAN JOURNAL OF IMMUNOLOGY ",

issn = "0014-2980",

number = "12",

}

Huemer, M, Rebhandl, S, Zaborsky, N, Gassner, FJ, Hainzl, S , Weiss, L, Hebenstreit, D, Greil, R & Geisberger, R 2014, 'AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.', EUROPEAN JOURNAL OF IMMUNOLOGY , vol. 44, no. 12, pp. 3747-3757. https://doi.org/10.1002/eji.201344421

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells. / Huemer, Michael (First author); Rebhandl, Stefan (Co-author); Zaborsky, Nadja (Co-author) et al.
In: EUROPEAN JOURNAL OF IMMUNOLOGY , Vol. 44, No. 12, 2014, p. 3747-3757.

Research output: Contribution to journal › Original Article (Journal) › peer-review

TY - JOUR

T1 - AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.

AU - Huemer, Michael

AU - Rebhandl, Stefan

AU - Zaborsky, Nadja

AU - Gassner, Franz J

AU - Hainzl, Stefan

AU - Weiss, Lukas

AU - Hebenstreit, Daniel

AU - Greil, Richard

AU - Geisberger, Roland

N1 - 1 Laboratory for Immunological and Molecular Cancer Research, Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria 2 Division of Experimental Dermatology and EB House Austria, Department of Dermatology, Paracelsus Medical University, Salzburg, Austria

PY - 2014

Y1 - 2014

KW - INDUCED CYTIDINE DEAMINASE

KW - V-H GENES

KW - SOMATIC HYPERMUTATION

KW - POOR-PROGNOSIS

KW - HOMOLOGOUS RECOMBINATION

KW - PROTEIN EXPRESSION

KW - SPLICE VARIANTS

KW - MESSENGER-RNA

KW - B-CELLS

KW - MUTATIONS

U2 - 10.1002/eji.201344421

DO - 10.1002/eji.201344421

M3 - Original Article (Journal)

C2 - 25179679

SN - 0014-2980

VL - 44

SP - 3747

EP - 3757

JO - EUROPEAN JOURNAL OF IMMUNOLOGY

JF - EUROPEAN JOURNAL OF IMMUNOLOGY

IS - 12

ER -

Huemer M, Rebhandl S, Zaborsky N, Gassner FJ, Hainzl S , Weiss L et al. AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells. EUROPEAN JOURNAL OF IMMUNOLOGY . 2014;44(12):3747-3757. doi: 10.1002/eji.201344421

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.

Keywords

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Projects

Elucidating signals required for proliferation of CLL cells in vivo using a tcl1tg mouse model for the disease

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