Adipositas beim Prader-Willi-Syndrom (PWS): Aktuelle Therapieansätze aus ernährungswissenschaftlicher und endokrinologisch-diabetologischer Sicht

Barbara Schweiger; Johannes Muehleder; Sandra Laimer

doi:10.1007/s41969-024-00244-4

Adipositas beim Prader-Willi-Syndrom (PWS): Aktuelle Therapieansätze aus ernährungswissenschaftlicher und endokrinologisch-diabetologischer Sicht

Translated title of the contribution: Obesity in Prader-Willi syndrome (PWS): Current therapeutic approaches from a nutritional and endocrinological-diabetological perspective

Barbara Schweiger^* (First author), Johannes Muehleder (Co-author), Sandra Laimer (Last author)

^*Corresponding author for this work

Department of Pediatrics

Research output: Contribution to journal › Original Article › peer-review

Abstract

Prader-Willi Syndrome is a genetically inherited condition in which a pathognomonic hyperphagia leads to obesity in almost all patients. Since obesity, with its comorbidities, is the main cause of death, treatment plays an important role. Medications have shown only moderate success in terms of Body Mass Index so far, but they can positively influence hyperphagia. Nutrition is the most important task in therapy management. It is important to consider the composition of meals and to implement age-appropriate behavioral measures. Despite new medications, obesity prevention remains the most important pillar for reducing morbidity and mortality.

Translated title of the contribution	Obesity in Prader-Willi syndrome (PWS): Current therapeutic approaches from a nutritional and endocrinological-diabetological perspective
Original language	German
Number of pages	5
Journal	Journal Fur Endokrinologie Diabetologie Und Stoffwechsel
Early online date	Aug 2024
DOIs	https://doi.org/10.1007/s41969-024-00244-4
Publication status	Published - 22 Aug 2024

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10.1007/s41969-024-00244-4

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title = "Adipositas beim Prader-Willi-Syndrom (PWS): Aktuelle Therapieans{\"a}tze aus ern{\"a}hrungswissenschaftlicher und endokrinologisch-diabetologischer Sicht",

abstract = "Prader-Willi Syndrome is a genetically inherited condition in which a pathognomonic hyperphagia leads to obesity in almost all patients. Since obesity, with its comorbidities, is the main cause of death, treatment plays an important role. Medications have shown only moderate success in terms of Body Mass Index so far, but they can positively influence hyperphagia. Nutrition is the most important task in therapy management. It is important to consider the composition of meals and to implement age-appropriate behavioral measures. Despite new medications, obesity prevention remains the most important pillar for reducing morbidity and mortality.",

keywords = "Diet, GLP-1 analogues, Hyperphagia, Syndromal Obesity",

author = "Barbara Schweiger and Johannes Muehleder and Sandra Laimer",

note = "alle: Department of Pediatrics, University Hospital Salzburg, Paracelsus Medical University, Salzburg, {\"O}sterreich",

year = "2024",

month = aug,

day = "22",

doi = "10.1007/s41969-024-00244-4",

language = "Deutsch",

journal = "Journal Fur Endokrinologie Diabetologie Und Stoffwechsel",

issn = "3004-8915",

publisher = "Springer Nature",

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Adipositas beim Prader-Willi-Syndrom (PWS): Aktuelle Therapieansätze aus ernährungswissenschaftlicher und endokrinologisch-diabetologischer Sicht. / Schweiger, Barbara (First author); Muehleder, Johannes (Co-author); Laimer, Sandra (Last author).
In: Journal Fur Endokrinologie Diabetologie Und Stoffwechsel, 22.08.2024.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Adipositas beim Prader-Willi-Syndrom (PWS)

T2 - Aktuelle Therapieansätze aus ernährungswissenschaftlicher und endokrinologisch-diabetologischer Sicht

AU - Schweiger, Barbara

AU - Muehleder, Johannes

AU - Laimer, Sandra

N1 - alle: Department of Pediatrics, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Österreich

PY - 2024/8/22

Y1 - 2024/8/22

N2 - Prader-Willi Syndrome is a genetically inherited condition in which a pathognomonic hyperphagia leads to obesity in almost all patients. Since obesity, with its comorbidities, is the main cause of death, treatment plays an important role. Medications have shown only moderate success in terms of Body Mass Index so far, but they can positively influence hyperphagia. Nutrition is the most important task in therapy management. It is important to consider the composition of meals and to implement age-appropriate behavioral measures. Despite new medications, obesity prevention remains the most important pillar for reducing morbidity and mortality.

AB - Prader-Willi Syndrome is a genetically inherited condition in which a pathognomonic hyperphagia leads to obesity in almost all patients. Since obesity, with its comorbidities, is the main cause of death, treatment plays an important role. Medications have shown only moderate success in terms of Body Mass Index so far, but they can positively influence hyperphagia. Nutrition is the most important task in therapy management. It is important to consider the composition of meals and to implement age-appropriate behavioral measures. Despite new medications, obesity prevention remains the most important pillar for reducing morbidity and mortality.

KW - Diet

KW - GLP-1 analogues

KW - Hyperphagia

KW - Syndromal Obesity

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U2 - 10.1007/s41969-024-00244-4

DO - 10.1007/s41969-024-00244-4

M3 - Originalarbeit

SN - 3004-8915

JO - Journal Fur Endokrinologie Diabetologie Und Stoffwechsel

JF - Journal Fur Endokrinologie Diabetologie Und Stoffwechsel

ER -

Adipositas beim Prader-Willi-Syndrom (PWS): Aktuelle Therapieansätze aus ernährungswissenschaftlicher und endokrinologisch-diabetologischer Sicht

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