Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

Tobias Kiesslich; Beate Alinger; Gernot Wolkersdörfer; Matthias Ocker; Daniel Neureiter; Frieder Berr

doi:10.3892/ijo_00000474

Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

Tobias Kiesslich (First author)
, Beate Alinger
, Gernot Wolkersdörfer (Co-author)
, Matthias Ocker
, Daniel Neureiter (Co-author)
, Frieder Berr^* (Last author)

^*Corresponding author for this work

Research output: Contribution to journal › Original Article › peer-review

39 Citations (Web of Science)

Original language	English
Pages (from-to)	49-58
Journal	INTERNATIONAL JOURNAL OF ONCOLOGY
Volume	36
Issue number	1
DOIs	https://doi.org/10.3892/ijo_00000474
Publication status	Published - 2010

Keywords

PROTEIN-KINASE CK2
BETA-CATENIN
CELL-LINES
HUMAN CHOLANGIOCARCINOMA
COLORECTAL-CANCER
IMMUNOHISTOCHEMICAL ANALYSIS
PHOTODYNAMIC TREATMENT
STEM-CELLS
E-CADHERIN
PATHWAY

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10.3892/ijo_00000474

Potenzial von Signalwegen der Embryonalentwicklung für neue Therapieansätze beim Gallengangskrebs
Berr, F. (PI)
1/02/10 → 29/07/10
Project: Research
Potential of Embryonic Signalling Pathways for Targeted Therapy of Cholangiocarcinoma
Berr, F. (PI)
16/06/08 → 16/08/08
Project: Research

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Kiesslich, T., Alinger, B., Wolkersdörfer, G., Ocker, M., Neureiter, D., & Berr, F. (2010). Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. INTERNATIONAL JOURNAL OF ONCOLOGY , 36(1), 49-58. https://doi.org/10.3892/ijo_00000474

Kiesslich, Tobias ; Alinger, Beate ; Wolkersdörfer, Gernot et al. / Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. In: INTERNATIONAL JOURNAL OF ONCOLOGY 2010 ; Vol. 36, No. 1. pp. 49-58.

@article{18d5b36abaf642bca1696220cd6993a3,

title = "Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition",

keywords = "PROTEIN-KINASE CK2, BETA-CATENIN, CELL-LINES, HUMAN CHOLANGIOCARCINOMA, COLORECTAL-CANCER, IMMUNOHISTOCHEMICAL ANALYSIS, PHOTODYNAMIC TREATMENT, STEM-CELLS, E-CADHERIN, PATHWAY",

author = "Tobias Kiesslich and Beate Alinger and Gernot Wolkersd{\"o}rfer and Matthias Ocker and Daniel Neureiter and Frieder Berr",

year = "2010",

doi = "10.3892/ijo\_00000474",

language = "English",

volume = "36",

pages = "49--58",

journal = "INTERNATIONAL JOURNAL OF ONCOLOGY ",

issn = "1019-6439",

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Kiesslich, T , Alinger, B, Wolkersdörfer, G, Ocker, M, Neureiter, D & Berr, F 2010, 'Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition', INTERNATIONAL JOURNAL OF ONCOLOGY , vol. 36, no. 1, pp. 49-58. https://doi.org/10.3892/ijo_00000474

Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. / Kiesslich, Tobias (First author); Alinger, Beate; Wolkersdörfer, Gernot (Co-author) et al.
In: INTERNATIONAL JOURNAL OF ONCOLOGY , Vol. 36, No. 1, 2010, p. 49-58.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

AU - Kiesslich, Tobias

AU - Alinger, Beate

AU - Wolkersdörfer, Gernot

AU - Ocker, Matthias

AU - Neureiter, Daniel

AU - Berr, Frieder

PY - 2010

Y1 - 2010

KW - PROTEIN-KINASE CK2

KW - BETA-CATENIN

KW - CELL-LINES

KW - HUMAN CHOLANGIOCARCINOMA

KW - COLORECTAL-CANCER

KW - IMMUNOHISTOCHEMICAL ANALYSIS

KW - PHOTODYNAMIC TREATMENT

KW - STEM-CELLS

KW - E-CADHERIN

KW - PATHWAY

U2 - 10.3892/ijo_00000474

DO - 10.3892/ijo_00000474

M3 - Original Article

C2 - 19956832

SN - 1019-6439

VL - 36

SP - 49

EP - 58

JO - INTERNATIONAL JOURNAL OF ONCOLOGY

JF - INTERNATIONAL JOURNAL OF ONCOLOGY

IS - 1

ER -

Kiesslich T , Alinger B, Wolkersdörfer G, Ocker M, Neureiter D , Berr F. Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. INTERNATIONAL JOURNAL OF ONCOLOGY . 2010;36(1):49-58. doi: 10.3892/ijo_00000474

Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

Keywords

Access to Document

Projects

Potenzial von Signalwegen der Embryonalentwicklung für neue Therapieansätze beim Gallengangskrebs

Potential of Embryonic Signalling Pathways for Targeted Therapy of Cholangiocarcinoma

Cite this