A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians

Lucia Liotti; Annamaria Bianchi; Giuseppe Crisafulli; Silvia Caimmi; Paolo Bottau; Fabrizio Franceschini; Rocco Luigi Valluzzi; Sara Riscassi; Francesca Saretta; Michele Miraglia Del Giudice; Carlo Caffarelli; Francesca Mori

doi:10.1186/s13052-025-02106-4

A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians

Lucia Liotti, Annamaria Bianchi, Giuseppe Crisafulli, Silvia Caimmi, Paolo Bottau, Fabrizio Franceschini, Rocco Luigi Valluzzi, Sara Riscassi, Francesca Saretta, Michele Miraglia Del Giudice, Carlo Caffarelli, Francesca Mori

Krankenhaus Bozen

Research output: Contribution to journal › Original Article › peer-review

Abstract

BACKGROUND: Several guidelines recommended how to manage delayed maculopapular exanthemas during antibiotic treatment. The aim of the present survey was to assess knowledge gaps of primary care pediatricians in managing children with delayed maculopapular exanthemas during a course of antibiotics.

METHODS: We conducted an online survey among primary care pediatricians in Italy, focusing on the management of children with maculopapular exanthemas occurring during antibiotic administration.

RESULTS: We found that 41% of pediatricians continued with the same antibiotic after the onset of mild to moderate maculopapular exanthemas. Additionally, only 25% took pictures of the skin manifestations during the acute phase, and 66% recorded the latency of the reaction.

CONCLUSIONS: Primary care management of children with suspected antibiotic induced maculopapular exanthemas is heterogeneous. Primary care physicians and allergists need to share common decisions and protocols to avoid mislabelling children as allergic to antibiotics.

Original language	English
Article number	264
Pages (from-to)	264
Number of pages	7
Journal	Italian journal of pediatrics
Volume	51
Issue number	1
DOIs	https://doi.org/10.1186/s13052-025-02106-4
Publication status	Published - 27 Aug 2025

Keywords

Humans
Anti-Bacterial Agents/adverse effects
Practice Patterns, Physicians'/statistics & numerical data
Primary Health Care
Surveys and Questionnaires
Child
Italy
Pediatricians
Male
Exanthema/chemically induced
Female
Drug Eruptions/therapy

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10.1186/s13052-025-02106-4

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Liotti, L., Bianchi, A., Crisafulli, G., Caimmi, S., Bottau, P., Franceschini, F., Valluzzi, R. L., Riscassi, S., Saretta, F., Miraglia Del Giudice, M., Caffarelli, C., & Mori, F. (2025). A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians. Italian journal of pediatrics, 51(1), 264. Article 264. https://doi.org/10.1186/s13052-025-02106-4

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title = "A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians",

abstract = "BACKGROUND: Several guidelines recommended how to manage delayed maculopapular exanthemas during antibiotic treatment. The aim of the present survey was to assess knowledge gaps of primary care pediatricians in managing children with delayed maculopapular exanthemas during a course of antibiotics.METHODS: We conducted an online survey among primary care pediatricians in Italy, focusing on the management of children with maculopapular exanthemas occurring during antibiotic administration.RESULTS: We found that 41\% of pediatricians continued with the same antibiotic after the onset of mild to moderate maculopapular exanthemas. Additionally, only 25\% took pictures of the skin manifestations during the acute phase, and 66\% recorded the latency of the reaction.CONCLUSIONS: Primary care management of children with suspected antibiotic induced maculopapular exanthemas is heterogeneous. Primary care physicians and allergists need to share common decisions and protocols to avoid mislabelling children as allergic to antibiotics.",

keywords = "Humans, Anti-Bacterial Agents/adverse effects, Practice Patterns, Physicians'/statistics \& numerical data, Primary Health Care, Surveys and Questionnaires, Child, Italy, Pediatricians, Male, Exanthema/chemically induced, Female, Drug Eruptions/therapy",

author = "Lucia Liotti and Annamaria Bianchi and Giuseppe Crisafulli and Silvia Caimmi and Paolo Bottau and Fabrizio Franceschini and Valluzzi, \{Rocco Luigi\} and Sara Riscassi and Francesca Saretta and \{Miraglia Del Giudice\}, Michele and Carlo Caffarelli and Francesca Mori",

note = "Lehr-KH Bolzano Hospital, Bolzano, Italy",

year = "2025",

month = aug,

day = "27",

doi = "10.1186/s13052-025-02106-4",

language = "English",

volume = "51",

pages = "264",

journal = "Italian journal of pediatrics",

issn = "1720-8424",

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Liotti, L, Bianchi, A, Crisafulli, G, Caimmi, S, Bottau, P, Franceschini, F, Valluzzi, RL, Riscassi, S, Saretta, F, Miraglia Del Giudice, M, Caffarelli, C & Mori, F 2025, 'A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians', Italian journal of pediatrics, vol. 51, no. 1, 264, pp. 264. https://doi.org/10.1186/s13052-025-02106-4

TY - JOUR

T1 - A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians

AU - Liotti, Lucia

AU - Bianchi, Annamaria

AU - Crisafulli, Giuseppe

AU - Caimmi, Silvia

AU - Bottau, Paolo

AU - Franceschini, Fabrizio

AU - Valluzzi, Rocco Luigi

AU - Riscassi, Sara

AU - Saretta, Francesca

AU - Miraglia Del Giudice, Michele

AU - Caffarelli, Carlo

AU - Mori, Francesca

N1 - Lehr-KH Bolzano Hospital, Bolzano, Italy

PY - 2025/8/27

Y1 - 2025/8/27

N2 - BACKGROUND: Several guidelines recommended how to manage delayed maculopapular exanthemas during antibiotic treatment. The aim of the present survey was to assess knowledge gaps of primary care pediatricians in managing children with delayed maculopapular exanthemas during a course of antibiotics.METHODS: We conducted an online survey among primary care pediatricians in Italy, focusing on the management of children with maculopapular exanthemas occurring during antibiotic administration.RESULTS: We found that 41% of pediatricians continued with the same antibiotic after the onset of mild to moderate maculopapular exanthemas. Additionally, only 25% took pictures of the skin manifestations during the acute phase, and 66% recorded the latency of the reaction.CONCLUSIONS: Primary care management of children with suspected antibiotic induced maculopapular exanthemas is heterogeneous. Primary care physicians and allergists need to share common decisions and protocols to avoid mislabelling children as allergic to antibiotics.

AB - BACKGROUND: Several guidelines recommended how to manage delayed maculopapular exanthemas during antibiotic treatment. The aim of the present survey was to assess knowledge gaps of primary care pediatricians in managing children with delayed maculopapular exanthemas during a course of antibiotics.METHODS: We conducted an online survey among primary care pediatricians in Italy, focusing on the management of children with maculopapular exanthemas occurring during antibiotic administration.RESULTS: We found that 41% of pediatricians continued with the same antibiotic after the onset of mild to moderate maculopapular exanthemas. Additionally, only 25% took pictures of the skin manifestations during the acute phase, and 66% recorded the latency of the reaction.CONCLUSIONS: Primary care management of children with suspected antibiotic induced maculopapular exanthemas is heterogeneous. Primary care physicians and allergists need to share common decisions and protocols to avoid mislabelling children as allergic to antibiotics.

KW - Humans

KW - Anti-Bacterial Agents/adverse effects

KW - Practice Patterns, Physicians'/statistics & numerical data

KW - Primary Health Care

KW - Surveys and Questionnaires

KW - Child

KW - Italy

KW - Pediatricians

KW - Male

KW - Exanthema/chemically induced

KW - Female

KW - Drug Eruptions/therapy

U2 - 10.1186/s13052-025-02106-4

DO - 10.1186/s13052-025-02106-4

M3 - Original Article

C2 - 40866903

SN - 1720-8424

VL - 51

SP - 264

JO - Italian journal of pediatrics

JF - Italian journal of pediatrics

IS - 1

M1 - 264

ER -

A survey of current management practices for delayed maculopapular exanthemas during antibiotic treatment among primary care pediatricians

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Keywords

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