A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.

Sabine Bernegger; Cyrill Brunner; Matej Vizovišek; Marko Fonovic; Gaetano Cuciniello; Flavia Giordano; Vesna Stanojlovic; Miroslaw Jarzab; Philip Simister; Stephan M Feller; Gerhard Obermeyer; Gernot Posselt; Boris Turk; Chiara Cabrele; Gisbert Schneider; Silja Wessler

doi:10.1038/s41598-020-67578-2

A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.

Sabine Bernegger, Cyrill Brunner, Matej Vizovišek, Marko Fonovic, Gaetano Cuciniello, Flavia Giordano, Vesna Stanojlovic, Miroslaw Jarzab, Philip Simister, Stephan M Feller, Gerhard Obermeyer, Gernot Posselt, Boris Turk, Chiara Cabrele, Gisbert Schneider, Silja Wessler

Institute of Molecular Regenerative Medicine

Research output: Contribution to journal › Original Article › peer-review

23 Citations (Web of Science)

Original language	English
Pages (from-to)	10563
Journal	Scientific reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-67578-2
Publication status	Published - 2020

Keywords

THERMAL SHIFT ASSAYS
SOLUBLE E-CADHERIN
PROTEASE
DEGP
IDENTIFICATION
CLEAVAGE
PROTEINS
HOMOLOGS
ADHESION
DESIGN

Access to Document

10.1038/s41598-020-67578-2

Cite this

Bernegger, S., Brunner, C., Vizovišek, M., Fonovic, M., Cuciniello, G., Giordano, F., Stanojlovic, V., Jarzab, M., Simister, P., Feller, S. M., Obermeyer, G., Posselt, G., Turk, B., Cabrele, C., Schneider, G., & Wessler, S. (2020). A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding. Scientific reports, 10(1), 10563. https://doi.org/10.1038/s41598-020-67578-2

@article{624649635302485d83dfe8bd9c3a4cb9,

title = "A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.",

keywords = "THERMAL SHIFT ASSAYS, SOLUBLE E-CADHERIN, PROTEASE, DEGP, IDENTIFICATION, CLEAVAGE, PROTEINS, HOMOLOGS, ADHESION, DESIGN",

author = "Sabine Bernegger and Cyrill Brunner and Matej Vizovi{\v s}ek and Marko Fonovic and Gaetano Cuciniello and Flavia Giordano and Vesna Stanojlovic and Miroslaw Jarzab and Philip Simister and Feller, \{Stephan M\} and Gerhard Obermeyer and Gernot Posselt and Boris Turk and Chiara Cabrele and Gisbert Schneider and Silja Wessler",

year = "2020",

doi = "10.1038/s41598-020-67578-2",

language = "English",

volume = "10",

pages = "10563",

journal = "Scientific reports",

issn = "2045-2322",

publisher = "Nature Publishing Group ",

number = "1",

}

Bernegger, S, Brunner, C, Vizovišek, M, Fonovic, M, Cuciniello, G, Giordano, F, Stanojlovic, V, Jarzab, M, Simister, P, Feller, SM, Obermeyer, G, Posselt, G, Turk, B, Cabrele, C, Schneider, G & Wessler, S 2020, 'A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.', Scientific reports, vol. 10, no. 1, pp. 10563. https://doi.org/10.1038/s41598-020-67578-2

TY - JOUR

T1 - A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding.

AU - Bernegger, Sabine

AU - Brunner, Cyrill

AU - Vizovišek, Matej

AU - Fonovic, Marko

AU - Cuciniello, Gaetano

AU - Giordano, Flavia

AU - Stanojlovic, Vesna

AU - Jarzab, Miroslaw

AU - Simister, Philip

AU - Feller, Stephan M

AU - Obermeyer, Gerhard

AU - Posselt, Gernot

AU - Turk, Boris

AU - Cabrele, Chiara

AU - Schneider, Gisbert

AU - Wessler, Silja

PY - 2020

Y1 - 2020

KW - THERMAL SHIFT ASSAYS

KW - SOLUBLE E-CADHERIN

KW - PROTEASE

KW - DEGP

KW - IDENTIFICATION

KW - CLEAVAGE

KW - PROTEINS

KW - HOMOLOGS

KW - ADHESION

KW - DESIGN

U2 - 10.1038/s41598-020-67578-2

DO - 10.1038/s41598-020-67578-2

M3 - Original Article

C2 - 32601479

SN - 2045-2322

VL - 10

SP - 10563

JO - Scientific reports

JF - Scientific reports

IS - 1

ER -