A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.

Madhuri Kalathur; Alberto Toso; Jingjing Chen; Ajinkya Revandkar; Claudia Danzer-Baltzer; Ilaria Guccini; Abdullah Alajati; Manuela Sarti; Sandra Pinton; Lara Brambilla; Diletta Di Mitri; Giuseppina Carbone; R Garcia-Escudero; Alessandro Padova; Letizia Magnoni; Alessia Tarditi; Laura Maccari; Federico Malusa; Ravi Kalathur; Lorenzo A Pinna; Giorgio Cozza; Maria Ruzzene; Nicolas Delaleu; Carlo V Catapano; Ian J Frew; Andrea Alimonti

doi:10.1038/ncomms8227

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.

Madhuri Kalathur, Alberto Toso, Jingjing Chen, Ajinkya Revandkar, Claudia Danzer-Baltzer, Ilaria Guccini, Abdullah Alajati, Manuela Sarti, Sandra Pinton, Lara Brambilla, Diletta Di Mitri, Giuseppina Carbone, R Garcia-Escudero, Alessandro Padova, Letizia Magnoni, Alessia Tarditi, Laura Maccari, Federico Malusa, Ravi Kalathur (Co-author), Lorenzo A PinnaGiorgio Cozza, Maria Ruzzene, Nicolas Delaleu, Carlo V Catapano, Ian J Frew, Andrea Alimonti

Institute of Experimental and Clinical Cell Therapy

Research output: Contribution to journal › Original Article › peer-review

34 Citations (Web of Science)

Original language	English
Pages (from-to)	7227
Journal	Nature Communications
Volume	6
DOIs	https://doi.org/10.1038/ncomms8227
Publication status	Published - 2015

Keywords

PROTEIN-KINASE CK2
CELL-CYCLE ARREST
PROSTATE-CANCER
INHIBITOR
SUPPRESSOR
PML
EXPRESSION
EFFICACY
POTENT
SURVEILLANCE

Access to Document

10.1038/ncomms8227

Cite this

Kalathur, M., Toso, A., Chen, J., Revandkar, A., Danzer-Baltzer, C., Guccini, I., Alajati, A., Sarti, M., Pinton, S., Brambilla, L., Di Mitri, D., Carbone, G., Garcia-Escudero, R., Padova, A., Magnoni, L., Tarditi, A., Maccari, L., Malusa, F., Kalathur, R., ... Alimonti, A. (2015). A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours. Nature Communications, 6, 7227. https://doi.org/10.1038/ncomms8227

@article{32ac8bec94ee4766b329ab4a4ac45fc1,

title = "A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.",

keywords = "PROTEIN-KINASE CK2, CELL-CYCLE ARREST, PROSTATE-CANCER, INHIBITOR, SUPPRESSOR, PML, EXPRESSION, EFFICACY, POTENT, SURVEILLANCE",

author = "Madhuri Kalathur and Alberto Toso and Jingjing Chen and Ajinkya Revandkar and Claudia Danzer-Baltzer and Ilaria Guccini and Abdullah Alajati and Manuela Sarti and Sandra Pinton and Lara Brambilla and {Di Mitri}, Diletta and Giuseppina Carbone and R Garcia-Escudero and Alessandro Padova and Letizia Magnoni and Alessia Tarditi and Laura Maccari and Federico Malusa and Ravi Kalathur and {A Pinna}, Lorenzo and Giorgio Cozza and Maria Ruzzene and Nicolas Delaleu and Catapano, {Carlo V} and Frew, {Ian J} and Andrea Alimonti",

note = "Ravi Kiran Reddy Kalathur: Experimental & Clinical Cell Therapy Institute, Spinal Cord & Tissue Regeneration Center Salzburg, Paracelsus Medizinische Privatuniversit{\"a}t, Strubergasse 21, A-5020, Salzburg, Austria ",

year = "2015",

doi = "10.1038/ncomms8227",

language = "English",

volume = "6",

pages = "7227",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "NATURE PORTFOLIO",

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Kalathur, M, Toso, A, Chen, J, Revandkar, A, Danzer-Baltzer, C, Guccini, I, Alajati, A, Sarti, M, Pinton, S, Brambilla, L, Di Mitri, D, Carbone, G, Garcia-Escudero, R, Padova, A, Magnoni, L, Tarditi, A, Maccari, L, Malusa, F, Kalathur, R, A Pinna, L, Cozza, G, Ruzzene, M, Delaleu, N, Catapano, CV, Frew, IJ & Alimonti, A 2015, 'A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.', Nature Communications, vol. 6, pp. 7227. https://doi.org/10.1038/ncomms8227

TY - JOUR

T1 - A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.

AU - Kalathur, Madhuri

AU - Toso, Alberto

AU - Chen, Jingjing

AU - Revandkar, Ajinkya

AU - Danzer-Baltzer, Claudia

AU - Guccini, Ilaria

AU - Alajati, Abdullah

AU - Sarti, Manuela

AU - Pinton, Sandra

AU - Brambilla, Lara

AU - Di Mitri, Diletta

AU - Carbone, Giuseppina

AU - Garcia-Escudero, R

AU - Padova, Alessandro

AU - Magnoni, Letizia

AU - Tarditi, Alessia

AU - Maccari, Laura

AU - Malusa, Federico

AU - Kalathur, Ravi

AU - A Pinna, Lorenzo

AU - Cozza, Giorgio

AU - Ruzzene, Maria

AU - Delaleu, Nicolas

AU - Catapano, Carlo V

AU - Frew, Ian J

AU - Alimonti, Andrea

N1 - Ravi Kiran Reddy Kalathur: Experimental & Clinical Cell Therapy Institute, Spinal Cord & Tissue Regeneration Center Salzburg, Paracelsus Medizinische Privatuniversität, Strubergasse 21, A-5020, Salzburg, Austria

PY - 2015

Y1 - 2015

KW - PROTEIN-KINASE CK2

KW - CELL-CYCLE ARREST

KW - PROSTATE-CANCER

KW - INHIBITOR

KW - SUPPRESSOR

KW - PML

KW - EXPRESSION

KW - EFFICACY

KW - POTENT

KW - SURVEILLANCE

U2 - 10.1038/ncomms8227

DO - 10.1038/ncomms8227

M3 - Original Article

C2 - 26085373

SN - 2041-1723

VL - 6

SP - 7227

JO - Nature Communications

JF - Nature Communications

ER -