A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.

Michael Schwemmlein; Matthias Peipp; Karin Barbin; Domenica Saul; Bernhard Stockmeyer; Roland Repp; Josef Birkmann; Fuat Oduncu; Bertold Emmerich; Georg H Fey

doi:10.1111/j.1365-2141.2005.05869.x

A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.

Michael Schwemmlein, Matthias Peipp, Karin Barbin, Domenica Saul, Bernhard Stockmeyer, Roland Repp, Josef Birkmann, Fuat Oduncu, Bertold Emmerich, Georg H Fey

Department of Internal Medicine V, Division of Oncology and Hematology

Research output: Contribution to journal › Original Article › peer-review

34 Citations (Web of Science)

Original language	English
Pages (from-to)	14-51
Journal	BRITISH JOURNAL OF HAEMATOLOGY
Volume	133
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2141.2005.05869.x
Publication status	Published - 2006

Keywords

ANTIBODY-TARGETED CHEMOTHERAPY
PHASE-I TRIAL
GEMTUZUMAB OZOGAMICIN
CYTOTOXIC ACTIVITY
PSEUDOMONAS EXOTOXIN
MONOCLONAL-ANTIBODY
1ST RELAPSE
PROTEINS
CD33
ANTI-CD33

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10.1111/j.1365-2141.2005.05869.x

Cite this

Schwemmlein, M., Peipp, M., Barbin, K., Saul, D., Stockmeyer, B., Repp, R., Birkmann, J., Oduncu, F., Emmerich, B., & Fey, G. H. (2006). A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. BRITISH JOURNAL OF HAEMATOLOGY , 133(2), 14-51. https://doi.org/10.1111/j.1365-2141.2005.05869.x

Schwemmlein, Michael ; Peipp, Matthias ; Barbin, Karin et al. / A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. In: BRITISH JOURNAL OF HAEMATOLOGY 2006 ; Vol. 133, No. 2. pp. 14-51.

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title = "A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.",

keywords = "ANTIBODY-TARGETED CHEMOTHERAPY, PHASE-I TRIAL, GEMTUZUMAB OZOGAMICIN, CYTOTOXIC ACTIVITY, PSEUDOMONAS EXOTOXIN, MONOCLONAL-ANTIBODY, 1ST RELAPSE, PROTEINS, CD33, ANTI-CD33",

author = "Michael Schwemmlein and Matthias Peipp and Karin Barbin and Domenica Saul and Bernhard Stockmeyer and Roland Repp and Josef Birkmann and Fuat Oduncu and Bertold Emmerich and Fey, {Georg H}",

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Schwemmlein, M, Peipp, M, Barbin, K, Saul, D, Stockmeyer, B, Repp, R, Birkmann, J, Oduncu, F, Emmerich, B & Fey, GH 2006, 'A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.', BRITISH JOURNAL OF HAEMATOLOGY , vol. 133, no. 2, pp. 14-51. https://doi.org/10.1111/j.1365-2141.2005.05869.x

A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. / Schwemmlein, Michael; Peipp, Matthias; Barbin, Karin et al.
In: BRITISH JOURNAL OF HAEMATOLOGY , Vol. 133, No. 2, 2006, p. 14-51.

Research output: Contribution to journal › Original Article › peer-review

TY - JOUR

T1 - A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.

AU - Schwemmlein, Michael

AU - Peipp, Matthias

AU - Barbin, Karin

AU - Saul, Domenica

AU - Stockmeyer, Bernhard

AU - Repp, Roland

AU - Birkmann, Josef

AU - Oduncu, Fuat

AU - Emmerich, Bertold

AU - Fey, Georg H

PY - 2006

Y1 - 2006

KW - ANTIBODY-TARGETED CHEMOTHERAPY

KW - PHASE-I TRIAL

KW - GEMTUZUMAB OZOGAMICIN

KW - CYTOTOXIC ACTIVITY

KW - PSEUDOMONAS EXOTOXIN

KW - MONOCLONAL-ANTIBODY

KW - 1ST RELAPSE

KW - PROTEINS

KW - CD33

KW - ANTI-CD33

U2 - 10.1111/j.1365-2141.2005.05869.x

DO - 10.1111/j.1365-2141.2005.05869.x

M3 - Original Article

C2 - 16611304

SN - 0007-1048

VL - 133

SP - 14

EP - 51

JO - BRITISH JOURNAL OF HAEMATOLOGY

JF - BRITISH JOURNAL OF HAEMATOLOGY

IS - 2

ER -

Schwemmlein M, Peipp M, Barbin K, Saul D, Stockmeyer B, Repp R et al. A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. BRITISH JOURNAL OF HAEMATOLOGY . 2006;133(2):14-51. doi: 10.1111/j.1365-2141.2005.05869.x