TY - JOUR
T1 - Value of Artificial Intelligence in Evaluating Lymph Node Metastases
AU - Caldonazzi, Nicolò
AU - Rizzo, Paola Chiara
AU - Eccher, Albino
AU - Girolami, Ilaria
AU - Fanelli, Giuseppe Nicolò
AU - Naccarato, Antonio Giuseppe
AU - Bonizzi, Giuseppina
AU - Fusco, Nicola
AU - d'Amati, Giulia
AU - Scarpa, Aldo
AU - Pantanowitz, Liron
AU - Marletta, Stefano
N1 - Lerh-KH Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversität, Provincial Hospital of Bolzano (SABES-ASDAA), 39100 Bolzano-Bozen, Italy
PY - 2023/4/26
Y1 - 2023/4/26
N2 - One of the most relevant prognostic factors in cancer staging is the presence of lymph node (LN) metastasis. Evaluating lymph nodes for the presence of metastatic cancerous cells can be a lengthy, monotonous, and error-prone process. Owing to digital pathology, artificial intelligence (AI) applied to whole slide images (WSIs) of lymph nodes can be exploited for the automatic detection of metastatic tissue. The aim of this study was to review the literature regarding the implementation of AI as a tool for the detection of metastases in LNs in WSIs. A systematic literature search was conducted in PubMed and Embase databases. Studies involving the application of AI techniques to automatically analyze LN status were included. Of 4584 retrieved articles, 23 were included. Relevant articles were labeled into three categories based upon the accuracy of AI in evaluating LNs. Published data overall indicate that the application of AI in detecting LN metastases is promising and can be proficiently employed in daily pathology practice.
AB - One of the most relevant prognostic factors in cancer staging is the presence of lymph node (LN) metastasis. Evaluating lymph nodes for the presence of metastatic cancerous cells can be a lengthy, monotonous, and error-prone process. Owing to digital pathology, artificial intelligence (AI) applied to whole slide images (WSIs) of lymph nodes can be exploited for the automatic detection of metastatic tissue. The aim of this study was to review the literature regarding the implementation of AI as a tool for the detection of metastases in LNs in WSIs. A systematic literature search was conducted in PubMed and Embase databases. Studies involving the application of AI techniques to automatically analyze LN status were included. Of 4584 retrieved articles, 23 were included. Relevant articles were labeled into three categories based upon the accuracy of AI in evaluating LNs. Published data overall indicate that the application of AI in detecting LN metastases is promising and can be proficiently employed in daily pathology practice.
U2 - 10.3390/cancers15092491
DO - 10.3390/cancers15092491
M3 - Review article
C2 - 37173958
SN - 2072-6694
VL - 15
JO - Cancers
JF - Cancers
IS - 9
ER -