Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells

Christian Reinhard Mayr; Tobias Kiesslich; Dino Bekric; Marlena Beyreis; Michael Kittl; Celina Ablinger; Elen Neureiter; Martin Pichler; Felix Prinz; Markus Ritter; Daniel Neureiter; Martin Jakab; Heidemarie Dobias

doi:10.1371/journal.pone.0287769

Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells

Christian Reinhard Mayr^* (Erstautor/-in), Tobias Kiesslich (Co-Autor/-in), Dino Bekric (Co-Autor/-in), Marlena Beyreis (Co-Autor/-in), Michael Kittl (Co-Autor/-in), Celina Ablinger, Elen Neureiter, Martin Pichler, Felix Prinz, Markus Ritter (Co-Autor/-in), Daniel Neureiter (Co-Autor/-in), Martin Jakab (Co-Autor/-in), Heidemarie Dobias (Letztautor/-in)

^*Korrespondierende/r Autor/-in für diese Arbeit

Publikation: Beitrag in Fachzeitschrift › Originalarbeit › Begutachtung

2 Quellenangaben (Web of Science)

Originalsprache	Englisch
Seiten (von - bis)	e0287769
Fachzeitschrift	PLOS ONE
Jahrgang	18
Ausgabenummer	6
DOIs	https://doi.org/10.1371/journal.pone.0287769
Publikationsstatus	Veröffentlicht - 30 Juni 2023

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10.1371/journal.pone.0287769

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@article{1e85475dbaa8486394e34b35b294ebbe,

title = "Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells",

keywords = "GROWTH-FACTOR RECEPTOR, NA+/K+-ATPASE, K+-ATPASE, CHOLANGIOCARCINOMA, APOPTOSIS, LINE, ESTABLISHMENT, SIGNAL, DEATH, SRC, Humans, Ouabain/pharmacology, Sodium-Potassium-Exchanging ATPase/genetics, Antineoplastic Agents/pharmacology, Biliary Tract Neoplasms/drug therapy, Apoptosis",

author = "Mayr, {Christian Reinhard} and Tobias Kiesslich and Dino Bekric and Marlena Beyreis and Michael Kittl and Celina Ablinger and Elen Neureiter and Martin Pichler and Felix Prinz and Markus Ritter and Daniel Neureiter and Martin Jakab and Heidemarie Dobias",

note = "Mayr, Kiesslich, Bekric, Beyreis, Kittl, E Neureiter, Ritter, D Neureiter, Jakab, Dobias: Center of Physiology, Pathophysiology and Biophysics, Institute of Physiology and Pathophysiology Salzburg, Paracelsus Medical University, Salzburg, Austria; Mayr, Kiesslich: Department of Internal Medicine I, University Clinics Salzburg, Paracelsus Medical University, Salzburg, Austria; Ablinger: Institute of Pharmacy, Paracelsus Medical University, Salzburg, Austria; Ritter, Jakab: Ludwig Boltzmann Institute for Arthritis und Rehabilitation, Paracelsus Medical University, Salzburg, Austria; Gastein Research Institute, Paracelsus Medical University, Salzburg, Austria; D Neureiter: Institute of Pathology, University Clinics Salzburg, Paracelsus Medical University, Salzburg, Austria",

year = "2023",

month = jun,

day = "30",

doi = "10.1371/journal.pone.0287769",

language = "English",

volume = "18",

pages = "e0287769",

journal = "PLOS ONE",

issn = "1932-6203",

publisher = "Public Library of Science ",

number = "6",

}

TY - JOUR

T1 - Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells

AU - Mayr, Christian Reinhard

AU - Kiesslich, Tobias

AU - Bekric, Dino

AU - Beyreis, Marlena

AU - Kittl, Michael

AU - Ablinger, Celina

AU - Neureiter, Elen

AU - Pichler, Martin

AU - Prinz, Felix

AU - Ritter, Markus

AU - Neureiter, Daniel

AU - Jakab, Martin

AU - Dobias, Heidemarie

N1 - Mayr, Kiesslich, Bekric, Beyreis, Kittl, E Neureiter, Ritter, D Neureiter, Jakab, Dobias: Center of Physiology, Pathophysiology and Biophysics, Institute of Physiology and Pathophysiology Salzburg, Paracelsus Medical University, Salzburg, Austria; Mayr, Kiesslich: Department of Internal Medicine I, University Clinics Salzburg, Paracelsus Medical University, Salzburg, Austria; Ablinger: Institute of Pharmacy, Paracelsus Medical University, Salzburg, Austria; Ritter, Jakab: Ludwig Boltzmann Institute for Arthritis und Rehabilitation, Paracelsus Medical University, Salzburg, Austria; Gastein Research Institute, Paracelsus Medical University, Salzburg, Austria; D Neureiter: Institute of Pathology, University Clinics Salzburg, Paracelsus Medical University, Salzburg, Austria

PY - 2023/6/30

Y1 - 2023/6/30

KW - GROWTH-FACTOR RECEPTOR

KW - NA+/K+-ATPASE

KW - K+-ATPASE

KW - CHOLANGIOCARCINOMA

KW - APOPTOSIS

KW - LINE

KW - ESTABLISHMENT

KW - SIGNAL

KW - DEATH

KW - SRC

KW - Humans

KW - Ouabain/pharmacology

KW - Sodium-Potassium-Exchanging ATPase/genetics

KW - Antineoplastic Agents/pharmacology

KW - Biliary Tract Neoplasms/drug therapy

KW - Apoptosis

U2 - 10.1371/journal.pone.0287769

DO - 10.1371/journal.pone.0287769

M3 - Original Article

C2 - 37390071

SN - 1932-6203

VL - 18

SP - e0287769

JO - PLOS ONE

JF - PLOS ONE

IS - 6

ER -