Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease.

Marius Wernig; Jian-Ping Zhao; Jan Pruszak; Eva Hedlund; Dongdong Fu; Frank Soldner; Vania Broccoli; Martha Constantine-Paton; Ole Isacson; Rudolf Jaenisch

doi:10.1073/pnas.0801677105

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease.

Marius Wernig, Jian-Ping Zhao, Jan Pruszak, Eva Hedlund, Dongdong Fu, Frank Soldner, Vania Broccoli, Martha Constantine-Paton, Ole Isacson, Rudolf Jaenisch

Publikation: Beitrag in Fachzeitschrift › Originalarbeit › Begutachtung

851 Quellenangaben (Web of Science)

Originalsprache	Englisch
Seiten (von - bis)	585-561
Fachzeitschrift	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Jahrgang	105
Ausgabenummer	15
DOIs	https://doi.org/10.1073/pnas.0801677105
Publikationsstatus	Veröffentlicht - 2008

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10.1073/pnas.0801677105

Dieses zitieren

Wernig, M., Zhao, J.-P., Pruszak, J., Hedlund, E., Fu, D., Soldner, F., Broccoli, V., Constantine-Paton, M., Isacson, O., & Jaenisch, R. (2008). Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 105(15), 585-561. https://doi.org/10.1073/pnas.0801677105

Wernig, Marius ; Zhao, Jian-Ping ; Pruszak, Jan et al. / Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease. in: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2008 ; Jahrgang 105, Nr. 15. S. 585-561.

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title = "Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease.",

keywords = "EMBRYONIC STEM-CELLS, DOPAMINERGIC-NEURONS, SUBSTANTIA-NIGRA, IN-VITRO, NUCLEAR TRANSPLANTATION, MIDBRAIN, THERAPY, MODEL, POPULATIONS, EXPRESSION",

author = "Marius Wernig and Jian-Ping Zhao and Jan Pruszak and Eva Hedlund and Dongdong Fu and Frank Soldner and Vania Broccoli and Martha Constantine-Paton and Ole Isacson and Rudolf Jaenisch",

year = "2008",

doi = "10.1073/pnas.0801677105",

language = "English",

volume = "105",

pages = "585--561",

journal = "PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA ",

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Wernig, M, Zhao, J-P, Pruszak, J, Hedlund, E, Fu, D, Soldner, F, Broccoli, V, Constantine-Paton, M, Isacson, O & Jaenisch, R 2008, 'Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease.', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Jg. 105, Nr. 15, S. 585-561. https://doi.org/10.1073/pnas.0801677105

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease. / Wernig, Marius; Zhao, Jian-Ping; Pruszak, Jan et al.
in: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Jahrgang 105, Nr. 15, 2008, S. 585-561.

Publikation: Beitrag in Fachzeitschrift › Originalarbeit › Begutachtung

TY - JOUR

T1 - Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease.

AU - Wernig, Marius

AU - Zhao, Jian-Ping

AU - Pruszak, Jan

AU - Hedlund, Eva

AU - Fu, Dongdong

AU - Soldner, Frank

AU - Broccoli, Vania

AU - Constantine-Paton, Martha

AU - Isacson, Ole

AU - Jaenisch, Rudolf

PY - 2008

Y1 - 2008

KW - EMBRYONIC STEM-CELLS

KW - DOPAMINERGIC-NEURONS

KW - SUBSTANTIA-NIGRA

KW - IN-VITRO

KW - NUCLEAR TRANSPLANTATION

KW - MIDBRAIN

KW - THERAPY

KW - MODEL

KW - POPULATIONS

KW - EXPRESSION

U2 - 10.1073/pnas.0801677105

DO - 10.1073/pnas.0801677105

M3 - Original Article

C2 - 18391196

SN - 0027-8424

VL - 105

SP - 585

EP - 561

JO - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JF - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IS - 15

ER -

Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinsons disease. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 2008;105(15):585-561. doi: 10.1073/pnas.0801677105