HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer

Christian Reinhard Mayr; Tobias Kiesslich; Sara Erber; Dino Bekric; Heidemarie Dobias; Marlena Beyreis; Markus Ritter; Tarkan Jäger; Bettina Neumayer; Paul Winkelmann; Eckhard Klieser; Daniel Neureiter

doi:10.3390/cancers13153862

HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer

Christian Reinhard Mayr^* (Erstautor/-in), Tobias Kiesslich (Co-Autor/-in), Sara Erber, Dino Bekric, Heidemarie Dobias (Co-Autor/-in), Marlena Beyreis (Co-Autor/-in), Markus Ritter (Co-Autor/-in), Tarkan Jäger (Co-Autor/-in), Bettina Neumayer (Co-Autor/-in), Paul Winkelmann, Eckhard Klieser (Co-Autor/-in), Daniel Neureiter (Letztautor/-in)

^*Korrespondierende/r Autor/-in für diese Arbeit

Publikation: Beitrag in Fachzeitschrift › Originalarbeit › Begutachtung

11 Quellenangaben (Web of Science)

Originalsprache	Englisch
Fachzeitschrift	Cancers
Jahrgang	13
Ausgabenummer	15
DOIs	https://doi.org/10.3390/cancers13153862
Publikationsstatus	Veröffentlicht - 31 Juli 2021

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10.3390/cancers13153862

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@article{908e5ca652aa4b4e82083370613ae7fa,

title = "HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer",

keywords = "HISTONE DEACETYLASE INHIBITOR, CARCINOMA-CELL-LINE, STEM-CELLS, CHOLANGIOCARCINOMA, ESTABLISHMENT, EXPRESSION, GROWTH, PROLIFERATION, TRICHOSTATIN, DEPSIPEPTIDE",

author = "Mayr, {Christian Reinhard} and Tobias Kiesslich and Sara Erber and Dino Bekric and Heidemarie Dobias and Marlena Beyreis and Markus Ritter and Tarkan J{\"a}ger and Bettina Neumayer and Paul Winkelmann and Eckhard Klieser and Daniel Neureiter",

note = "Mayr; Kiesslich; Erber; Bekric; Dobias; Beyreis; Ritter: Paracelsus Med Univ, Inst Physiol *** Pathophysiol Salzburg, Ctr Physiol Pathophysiol *** Biophys Salzburg *** Nur, Strubergasse 22, A-5020 Salzburg, Austria; Mayr; Kiesslich: Paracelsus Med Univ, Univ Clin Salzburg, Dept Internal Med 1, Mullner Hauptstr 48, A-5020 Salzburg, Austria; Ritter: Paracelsus Med Univ, Ludwig Boltzmann Inst Arthrit *** Rehabil, Strubergasse 22, A-5020 Salzburg, Austria; J{\"a}ger: Paracelsus Med Univ, Univ Clin Salzburg, Dept Surg, Mullner Hauptstr 48, A-5020 Salzburg, Austria; Neumayer; Winkelmann; Klieser; Neureiter: Paracelsus Med Univ, Univ Clin Salzburg, Inst Pathol, Mullner Hauptstr 48, A-5020 Salzburg, Austria;",

year = "2021",

month = jul,

day = "31",

doi = "10.3390/cancers13153862",

language = "English",

volume = "13",

journal = "Cancers",

issn = "2072-6694",

publisher = "MDPI",

number = "15",

}

TY - JOUR

T1 - HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer

AU - Mayr, Christian Reinhard

AU - Kiesslich, Tobias

AU - Erber, Sara

AU - Bekric, Dino

AU - Dobias, Heidemarie

AU - Beyreis, Marlena

AU - Ritter, Markus

AU - Jäger, Tarkan

AU - Neumayer, Bettina

AU - Winkelmann, Paul

AU - Klieser, Eckhard

AU - Neureiter, Daniel

N1 - Mayr; Kiesslich; Erber; Bekric; Dobias; Beyreis; Ritter: Paracelsus Med Univ, Inst Physiol *** Pathophysiol Salzburg, Ctr Physiol Pathophysiol *** Biophys Salzburg *** Nur, Strubergasse 22, A-5020 Salzburg, Austria; Mayr; Kiesslich: Paracelsus Med Univ, Univ Clin Salzburg, Dept Internal Med 1, Mullner Hauptstr 48, A-5020 Salzburg, Austria; Ritter: Paracelsus Med Univ, Ludwig Boltzmann Inst Arthrit *** Rehabil, Strubergasse 22, A-5020 Salzburg, Austria; Jäger: Paracelsus Med Univ, Univ Clin Salzburg, Dept Surg, Mullner Hauptstr 48, A-5020 Salzburg, Austria; Neumayer; Winkelmann; Klieser; Neureiter: Paracelsus Med Univ, Univ Clin Salzburg, Inst Pathol, Mullner Hauptstr 48, A-5020 Salzburg, Austria;

PY - 2021/7/31

Y1 - 2021/7/31

KW - HISTONE DEACETYLASE INHIBITOR

KW - CARCINOMA-CELL-LINE

KW - STEM-CELLS

KW - CHOLANGIOCARCINOMA

KW - ESTABLISHMENT

KW - EXPRESSION

KW - GROWTH

KW - PROLIFERATION

KW - TRICHOSTATIN

KW - DEPSIPEPTIDE

U2 - 10.3390/cancers13153862

DO - 10.3390/cancers13153862

M3 - Original Article

C2 - 34359763

SN - 2072-6694

VL - 13

JO - Cancers

JF - Cancers

IS - 15

ER -