Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report

F Kalantari; G Schweighofer-Zwink; G Rendl; C Pirich; M Beheshti

doi:10.1186/s43055-023-01107-9

Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report

F Kalantari, G Schweighofer-Zwink (Co-Autor/-in), G Rendl (Co-Autor/-in), C Pirich (Co-Autor/-in), M Beheshti^* (Letztautor/-in)

^*Korrespondierende/r Autor/-in für diese Arbeit

Universitätsklinikum für Nuklearmedizin und Endokrinologie

Publikation: Beitrag in Fachzeitschrift › Fallbericht › Begutachtung

Abstract

BackgroundThis case represents one of the largest adrenal metastases in the literature and highlights the importance of accurate imaging in clinical management of patients with advanced malignant melanoma.Case presentationA 67-year-old female with an ulcerated malignant melanoma presented with an asymptomatic 18-cm left adrenal mass on 18F-FDG PET/CT staging. After two cycles of combined systemic immunotherapy, an impressive shrinkage of the adrenal metastatic tumor was observed on 18F-FDG PET/CT imaging.ConclusionsThe case emphasizes the potential of 18F-FDG PET/CT as a functional imaging modality for accurate staging and precise early assessment of response to immunotherapy. Overall, this report highlights the importance of accurate imaging for the effective management of adrenal metastases in melanoma patients.

Originalsprache	Englisch
Aufsatznummer	158
Seitenumfang	3
Fachzeitschrift	EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE
Jahrgang	54
Ausgabenummer	1
DOIs	https://doi.org/10.1186/s43055-023-01107-9
Publikationsstatus	Veröffentlicht - 20 Sept. 2023

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10.1186/s43055-023-01107-9

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@article{f1ce907cb97648c48bb1795c0dfe69ea,

title = "Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report",

abstract = "BackgroundThis case represents one of the largest adrenal metastases in the literature and highlights the importance of accurate imaging in clinical management of patients with advanced malignant melanoma.Case presentationA 67-year-old female with an ulcerated malignant melanoma presented with an asymptomatic 18-cm left adrenal mass on 18F-FDG PET/CT staging. After two cycles of combined systemic immunotherapy, an impressive shrinkage of the adrenal metastatic tumor was observed on 18F-FDG PET/CT imaging.ConclusionsThe case emphasizes the potential of 18F-FDG PET/CT as a functional imaging modality for accurate staging and precise early assessment of response to immunotherapy. Overall, this report highlights the importance of accurate imaging for the effective management of adrenal metastases in melanoma patients.",

keywords = "Malignant melanoma, 18F-FDG PET/CT, Adrenal metastases",

author = "F Kalantari and G Schweighofer-Zwink and G Rendl and C Pirich and M Beheshti",

note = "alle: Division of Molecular Imaging and Theranostics, Department of Nuclear Medicine and Endocrinology, University Hospital Salzburg, Paracelsus Medical University, Muellner Hauptstrasse 48",

year = "2023",

month = sep,

day = "20",

doi = "10.1186/s43055-023-01107-9",

language = "English",

volume = "54",

journal = "EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE",

issn = "2090-4762",

number = "1",

}

Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report. / Kalantari, F; Schweighofer-Zwink, G (Co-Autor/-in); Rendl, G (Co-Autor/-in) et al.
in: EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE, Jahrgang 54, Nr. 1, 158, 20.09.2023.

Publikation: Beitrag in Fachzeitschrift › Fallbericht › Begutachtung

TY - JOUR

T1 - Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report

AU - Kalantari, F

AU - Schweighofer-Zwink, G

AU - Rendl, G

AU - Pirich, C

AU - Beheshti, M

N1 - alle: Division of Molecular Imaging and Theranostics, Department of Nuclear Medicine and Endocrinology, University Hospital Salzburg, Paracelsus Medical University, Muellner Hauptstrasse 48

PY - 2023/9/20

Y1 - 2023/9/20

N2 - BackgroundThis case represents one of the largest adrenal metastases in the literature and highlights the importance of accurate imaging in clinical management of patients with advanced malignant melanoma.Case presentationA 67-year-old female with an ulcerated malignant melanoma presented with an asymptomatic 18-cm left adrenal mass on 18F-FDG PET/CT staging. After two cycles of combined systemic immunotherapy, an impressive shrinkage of the adrenal metastatic tumor was observed on 18F-FDG PET/CT imaging.ConclusionsThe case emphasizes the potential of 18F-FDG PET/CT as a functional imaging modality for accurate staging and precise early assessment of response to immunotherapy. Overall, this report highlights the importance of accurate imaging for the effective management of adrenal metastases in melanoma patients.

AB - BackgroundThis case represents one of the largest adrenal metastases in the literature and highlights the importance of accurate imaging in clinical management of patients with advanced malignant melanoma.Case presentationA 67-year-old female with an ulcerated malignant melanoma presented with an asymptomatic 18-cm left adrenal mass on 18F-FDG PET/CT staging. After two cycles of combined systemic immunotherapy, an impressive shrinkage of the adrenal metastatic tumor was observed on 18F-FDG PET/CT imaging.ConclusionsThe case emphasizes the potential of 18F-FDG PET/CT as a functional imaging modality for accurate staging and precise early assessment of response to immunotherapy. Overall, this report highlights the importance of accurate imaging for the effective management of adrenal metastases in melanoma patients.

KW - Malignant melanoma

KW - 18F-FDG PET/CT

KW - Adrenal metastases

U2 - 10.1186/s43055-023-01107-9

DO - 10.1186/s43055-023-01107-9

M3 - Case report

SN - 2090-4762

VL - 54

JO - EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE

JF - EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE

IS - 1

M1 - 158

ER -

Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report

Abstract

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