TY - JOUR
T1 - Contemporary assessment of short- and functional 90-days outcome in old intensive care patients suffering from COVID-19
AU - Bruno, Raphael Romano
AU - Wernly, Bernhard
AU - Artigas, Antonio
AU - Fuest, Kristina
AU - Schaller, Stefan J.
AU - Dannenberg, Lisa
AU - Kindgen-Milles, Detlef
AU - Kelm, Malte
AU - Beil, Michael
AU - Sviri, Sigal
AU - Elhadi, Muhammed
AU - Joannidis, Michael
AU - Oeyen, Sandra
AU - Kondili, Eumorfia
AU - Moreno, Rui
AU - Leaver, Susannah
AU - Guidet, Bertrand
AU - De Lange, Dylan W.
AU - Flaatten, Hans
AU - Szczeklik, Wojciech
AU - Jung, Christian
AU - COVIP Study Grp
N1 - Wernly: Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University, Salzburg, Austria; Institute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University of Salzburg, Salzburg, Austria
PY - 2024/12
Y1 - 2024/12
N2 - Purpose: There are limited data about the outcome of old intensive care (ICU) patients suffering from Covid-19 in the post-vaccination era. This study distinguishes the pre- and post-acute illness living conditions of ICU survivors from non-survivors. Methods: This prospective international multicenter study included 642 old (>= 70 years) ICU patients, including data ranging from pre-illness condition to functional 90-days follow-up. The primary endpoint was the difference of living conditions of ICU-survivors before ICU admission and 90-days after ICU discharge. Secondary outcomes were 90-days mortality, and quality of life. Results: A total of 642 patients were included. Significantly more ICU survivors lived at their own homes without support before ICU admission than non-survivors (p = 0.016), while more non-survivors resided in nursing homes (p = 0.016). ICU mortality was 39 %, 30-days and 90 days mortality were 47 %and 55 %. After 90 days, only 22 % maintained the same living conditions. Surviving patients viewed ICU admission positively after 90 days, while relatives were more uncertain. Quality of life indicated a self-reported average score of 60 (50-75). Conclusion: Living conditions influence the outcome of critically ill old patients suffering from Covid-19. Only a minority returned to their initial habitat after ICU survival. Trial registration number NCT04321265
AB - Purpose: There are limited data about the outcome of old intensive care (ICU) patients suffering from Covid-19 in the post-vaccination era. This study distinguishes the pre- and post-acute illness living conditions of ICU survivors from non-survivors. Methods: This prospective international multicenter study included 642 old (>= 70 years) ICU patients, including data ranging from pre-illness condition to functional 90-days follow-up. The primary endpoint was the difference of living conditions of ICU-survivors before ICU admission and 90-days after ICU discharge. Secondary outcomes were 90-days mortality, and quality of life. Results: A total of 642 patients were included. Significantly more ICU survivors lived at their own homes without support before ICU admission than non-survivors (p = 0.016), while more non-survivors resided in nursing homes (p = 0.016). ICU mortality was 39 %, 30-days and 90 days mortality were 47 %and 55 %. After 90 days, only 22 % maintained the same living conditions. Surviving patients viewed ICU admission positively after 90 days, while relatives were more uncertain. Quality of life indicated a self-reported average score of 60 (50-75). Conclusion: Living conditions influence the outcome of critically ill old patients suffering from Covid-19. Only a minority returned to their initial habitat after ICU survival. Trial registration number NCT04321265
KW - COVIP-study
KW - Covid-19
KW - Elderly
KW - Long-term outcomes
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pmu_pure&SrcAuth=WosAPI&KeyUT=WOS:001375270300001&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1016/j.jcrc.2024.154984
DO - 10.1016/j.jcrc.2024.154984
M3 - Original Article
C2 - 39631193
SN - 0883-9441
VL - 86
JO - JOURNAL OF CRITICAL CARE
JF - JOURNAL OF CRITICAL CARE
M1 - 154984
ER -