TY - JOUR
T1 - Cardiovascular disease as part of Long COVID
T2 - A systematic review
AU - Tsampasian, Vasiliki
AU - Bäck, Maria
AU - Bernardi, Marco
AU - Cavarretta, Elena
AU - Dębski, Maciej
AU - Gati, Sabiha
AU - Hansen, Dominique
AU - Kränkel, Nicolle
AU - Koskinas, Konstantinos
AU - Niebauer, Josef
AU - Spadafora, Luigi
AU - Frias Vargas, Manuel
AU - Biondi-Zoccai, Giuseppe
AU - Vassiliou, Vassilios S
N1 - © The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.
PY - 2024/2/21
Y1 - 2024/2/21
N2 - Aims Long COVID syndrome has had a major impact on million patients' lives worldwide. The cardiovascular system is an important aspect of this multifaceted disease that may manifest in many ways. We have hereby performed a narrative review in order to identify the extent of the cardiovascular manifestations of the Long COVID syndrome.Methods and results An in-depth systematic search of the literature has been conducted for this narrative review. The systematic search of PubMed and Cochrane databases yielded 3993 articles, of which 629 underwent full-text screening. A total of 78 studies were included in the final qualitative synthesis and data evaluation. The pathophysiology of the cardiovascular sequelae of Long COVID syndrome and the cardiac manifestations and complications of Long COVID syndrome are critically evaluated. In addition, potential cardiovascular risk factors are assessed, and preventive methods and treatment options are examined in this review.Conclusion This systematic review poignantly summarizes the evidence from the available literature regarding the cardiovascular manifestations of Long COVID syndrome and reviews potential mechanistic pathways, diagnostic approaches, preventive measures, and treatment options.Graphical Abstract
AB - Aims Long COVID syndrome has had a major impact on million patients' lives worldwide. The cardiovascular system is an important aspect of this multifaceted disease that may manifest in many ways. We have hereby performed a narrative review in order to identify the extent of the cardiovascular manifestations of the Long COVID syndrome.Methods and results An in-depth systematic search of the literature has been conducted for this narrative review. The systematic search of PubMed and Cochrane databases yielded 3993 articles, of which 629 underwent full-text screening. A total of 78 studies were included in the final qualitative synthesis and data evaluation. The pathophysiology of the cardiovascular sequelae of Long COVID syndrome and the cardiac manifestations and complications of Long COVID syndrome are critically evaluated. In addition, potential cardiovascular risk factors are assessed, and preventive methods and treatment options are examined in this review.Conclusion This systematic review poignantly summarizes the evidence from the available literature regarding the cardiovascular manifestations of Long COVID syndrome and reviews potential mechanistic pathways, diagnostic approaches, preventive measures, and treatment options.Graphical Abstract
U2 - 10.1093/eurjpc/zwae070
DO - 10.1093/eurjpc/zwae070
M3 - Review article
C2 - 38381595
SN - 2047-4873
JO - EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
JF - EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
ER -