AO Spine Clinical Practice Recommendations for the Management of Subaxial Spine Fractures

Study design Literature Review with clinical recommendations.Objective To highlight impactful studies on subaxial cervical fractures, identified by the AO Spine Knowledge Forum Trauma and Infection group, with recommendations for their integration into clinical practice.Methods Four studies on subaxial cervical fractures that have the potential to shape current practice in subaxial cervical fractures were selected and reviewed. Each study was chosen for its contribution to a critical phase in subaxial fractures management: diagnosis and imaging, surgical vs conservative treatment, and selection of approach.Results Four studies were highlighted. Article 1: Rutsch et al evaluated the sensitivity and specificity of CT, MRI, plain radiography, and LODOX-Statscan in identifying cervical spine injuries. We strongly recommend the use of CT/MRI as gold standard for radiological workup in cervical spine injuries. Article 2: Cirillo et al performed a systematic review of predictor of failure to conservative treatment for isolated unilateral facet fractures. We conditionally recommend surgical treatment in floating lateral mass and greater fragment size. Article 3: Singh et al evaluated the predictors of failure after stand-alone ACDF in subaxial fractures. We conditionally recommend adding posterior fusion in PLL injury, bilateral facet joint dislocation and age above 60 years. Article 4: Kwon et al prospectively randomized and compared anterior vs posterior approach in unilateral facet joint injury. We conditionally recommend anterior surgical fixation in unilateral facet injuries without spinal cord injury.Conclusion This article provides spine surgeons with evidence-based recommendations to enhance standardization and effectiveness of the management of subaxial spine fractures.